ono 1078 has been researched along with Cerebral Ischemia in 11 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats." | 7.72 | [Protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats]. ( Chen, Z; Wei, EQ; Zhang, SF; Zhang, SH; Zhu, CY, 2004) |
| "Montelukast was injected intraperitoneally either as multiple doses (once a day for 3 days and 30 min before MCAO) or as a single dose (at 30 min before, 30 min after, or 1 h after MCAO), respectively, and pranlukast and edaravone were used as controls." | 5.33 | Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice. ( Chen, Z; Chu, LS; Mei, RH; Wei, EQ; Xu, HM; Yu, GL; Zhang, Q; Zhang, SH; Zhang, WP; Zhao, MH, 2005) |
| "To determine the protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats." | 3.72 | [Protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats]. ( Chen, Z; Wei, EQ; Zhang, SF; Zhang, SH; Zhu, CY, 2004) |
| "Montelukast was injected intraperitoneally either as multiple doses (once a day for 3 days and 30 min before MCAO) or as a single dose (at 30 min before, 30 min after, or 1 h after MCAO), respectively, and pranlukast and edaravone were used as controls." | 1.33 | Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice. ( Chen, Z; Chu, LS; Mei, RH; Wei, EQ; Xu, HM; Yu, GL; Zhang, Q; Zhang, SH; Zhang, WP; Zhao, MH, 2005) |
| "Focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO)." | 1.33 | Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice. ( Chen, Z; Chu, LS; Fang, SH; Wang, ML; Wei, EQ; Weng, JQ; Yu, GL; Zhang, LH; Zhang, Q; Zhang, SH; Zhang, WP; Zhou, Y, 2005) |
| "Focal cerebral ischemia in mice was induced by permanent middle cerebral artery occlusion (MCAO)." | 1.33 | Pranlukast reduces neutrophil but not macrophage/microglial accumulation in brain after focal cerebral ischemia in mice. ( Chu, LS; Fang, SH; Wang, ML; Wei, EQ; Yu, GL; Zhang, WP; Zhou, Y, 2006) |
| "Transient global cerebral ischemia was induced by four-vessel occlusion for 10 min and followed by 72-h reperfusion." | 1.32 | Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on transient global cerebral ischemia in rats. ( Wei, EQ; Zhang, LH, 2003) |
| "After middle cerebral artery occlusion (MCAO), the neurological deficits were evaluated 24 h later." | 1.32 | [An improved quantitative method for evaluating neurological deficits in mice with focal cerebral ischemia]. ( Wei, EQ; Xu, QQ; Yu, YP; Zheng, MZ; Zhu, CY; Zhu, YF, 2003) |
| "Focal cerebral ischemia was induced by permanent middle cerebral artery (MCA) occlusion in mice." | 1.31 | [Protective effect of ONO-1078, a leukotriene antagonist, on focal cerebral ischemia in mice]. ( Wang, PL; Wang, RD; Wei, EQ; Zeng, LH; Zhang, WP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (81.82) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, QJ | 1 |
| Wang, H | 1 |
| Liu, ZX | 1 |
| Fang, SH | 5 |
| Song, XM | 1 |
| Lu, YB | 2 |
| Zhang, WP | 7 |
| Sa, XY | 1 |
| Ying, HZ | 1 |
| Wei, EQ | 11 |
| Lin, KN | 1 |
| Huang, XQ | 1 |
| Zeng, LH | 1 |
| Wang, RD | 1 |
| Wang, PL | 1 |
| Zhang, LH | 2 |
| Zhu, CY | 2 |
| Xu, QQ | 1 |
| Yu, YP | 1 |
| Zhu, YF | 1 |
| Zheng, MZ | 1 |
| Zhang, SH | 3 |
| Chen, Z | 4 |
| Zhang, SF | 1 |
| Li, W | 1 |
| Wang, ML | 4 |
| Liu, LY | 1 |
| Yu, GL | 4 |
| Xu, HM | 1 |
| Chu, LS | 4 |
| Zhang, Q | 2 |
| Mei, RH | 1 |
| Zhao, MH | 1 |
| Weng, JQ | 1 |
| Zhou, Y | 3 |
11 other studies available for ono 1078 and Cerebral Ischemia
| Article | Year |
|---|---|
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats.
Topics: Acute Disease; Animals; Brain; Brain Edema; Brain Ischemia; Chromones; Cyclohexanecarboxylic Acids; | 2015 |
Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells.
Topics: Apoptosis; Brain Ischemia; Cell Culture Techniques; Cell Hypoxia; Cell Line; Cell Membrane; Cell Nuc | 2012 |
[Protective effect of ONO-1078, a leukotriene antagonist, on focal cerebral ischemia in mice].
Topics: Animals; Brain; Brain Ischemia; Chromones; Dexamethasone; Infarction, Middle Cerebral Artery; Leukot | 2001 |
Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on transient global cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chromones; Disease Models, Animal; Hippocampus; Ischemic A | 2003 |
[An improved quantitative method for evaluating neurological deficits in mice with focal cerebral ischemia].
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Chromones; Female; Hippocampus; Infarction, Middle | 2003 |
[Protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats].
Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Chromo | 2004 |
[Effects of edaravone, minocycline and ONO-1078 on oxygen/glucose deprivation-induced electrophysiological alteration in rat hippocampal slices].
Topics: Animals; Anti-Bacterial Agents; Antipyrine; Brain Ischemia; Chromones; Edaravone; Evoked Potentials; | 2004 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice.
Topics: Acetates; Animals; Antipyrine; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Chromones; C | 2005 |
Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Ischemia; Cell Count; Chromones; Chronic Dise | 2005 |
Pranlukast reduces neutrophil but not macrophage/microglial accumulation in brain after focal cerebral ischemia in mice.
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Ischemia; CD11b Antigen; Chromones; Immunoglobulin G | 2006 |
Increased expression of cysteinyl leukotriene receptor-1 in the brain mediates neuronal damage and astrogliosis after focal cerebral ischemia in rats.
Topics: Animals; Astrocytes; Brain Ischemia; Cerebral Infarction; Chromones; Disease Models, Animal; Encepha | 2006 |