ono 1078 has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herrando-Grabulosa, M | 1 |
| Mulet, R | 1 |
| Pujol, A | 1 |
| Mas, JM | 1 |
| Navarro, X | 1 |
| Aloy, P | 1 |
| Coma, M | 1 |
| Casas, C | 1 |
1 other study available for ono 1078 and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems.
Topics: Algorithms; Amyotrophic Lateral Sclerosis; Animals; Chromones; Computer Simulation; Drug Therapy, Co | 2016 |