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ondansetron and Uremia

ondansetron has been researched along with Uremia in 7 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Pregabalin is an effective alternative for treatment of uraemic pruritus."9.20Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015)
"The results obtained showed that ondansetron was more effective in controlling nausea and vomiting than metoclopramide, either objectively (2."9.10Comparison of ondansetron with metoclopramide in the symptomatic relief of uremia-induced nausea and vomiting. ( Bagatin, J; Hozo, I; Ljutić, D; Perković, D; Pivac, N; Rumboldt, Z, 2002)
"This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus."8.88The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012)
"Pruritus is a common, unpleasant symptom of uremic patients."6.69Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998)
"Pruritus is a distressing symptom affecting up to 90% of dialysis patients."6.69Ondansetron therapy for uremic pruritus in hemodialysis patients. ( Ashmore, SD; Chrystyn, H; Daly, MJ; Jones, CH; Newstead, CG, 2000)
"Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron."5.32Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004)
"Pregabalin is an effective alternative for treatment of uraemic pruritus."5.20Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015)
"The results obtained showed that ondansetron was more effective in controlling nausea and vomiting than metoclopramide, either objectively (2."5.10Comparison of ondansetron with metoclopramide in the symptomatic relief of uremia-induced nausea and vomiting. ( Bagatin, J; Hozo, I; Ljutić, D; Perković, D; Pivac, N; Rumboldt, Z, 2002)
"This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus."4.88The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012)
"Pruritus is a common, unpleasant symptom of uremic patients."2.69Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998)
"Pruritus is a distressing symptom affecting up to 90% of dialysis patients."2.69Ondansetron therapy for uremic pruritus in hemodialysis patients. ( Ashmore, SD; Chrystyn, H; Daly, MJ; Jones, CH; Newstead, CG, 2000)
"Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron."1.32Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yue, J1
Jiao, S1
Xiao, Y1
Ren, W1
Zhao, T1
Meng, J1
To, TH1
Clark, K1
Lam, L1
Shelby-James, T1
Currow, DC1
Deshpande, PV1
Andrews, PA1
Quan, V1
Ogg, CS1
Balaskas, EV1
Bamihas, GI1
Karamouzis, M1
Voyiatzis, G1
Tourkantonis, A1
Ashmore, SD1
Jones, CH1
Newstead, CG1
Daly, MJ1
Chrystyn, H1
Ljutić, D1
Perković, D1
Rumboldt, Z1
Bagatin, J1
Hozo, I1
Pivac, N1

Reviews

1 review available for ondansetron and Uremia

ArticleYear
The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review.
    Journal of pain and symptom management, 2012, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cholestasis; Female; Humans; Male; Middle Aged; Ondansetron; Pruritu

2012

Trials

4 trials available for ondansetron and Uremia

ArticleYear
Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study.
    International urology and nephrology, 2015, Volume: 47, Issue:1

    Topics: Adult; Aged; Analgesics; Antipruritics; Double-Blind Method; Drug Therapy, Combination; Female; gamm

2015
Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients.
    Nephron, 1998, Volume: 78, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Histamine; Humans; Kidney Failure, Chr

1998
Ondansetron therapy for uremic pruritus in hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 35, Issue:5

    Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Ondansetron

2000
Comparison of ondansetron with metoclopramide in the symptomatic relief of uremia-induced nausea and vomiting.
    Kidney & blood pressure research, 2002, Volume: 25, Issue:1

    Topics: Adult; Aged; Antiemetics; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Metoclopram

2002

Other Studies

2 other studies available for ondansetron and Uremia

ArticleYear
Ondansetron for paediatric uraemic pruritus: a case report.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:6

    Topics: Adolescent; Antipruritics; Female; Humans; Kidney Failure, Chronic; Ondansetron; Peritoneal Dialysis

2004
Ondansetron for symptomatic relief in terminal uraemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10, Issue:1

    Topics: Administration, Oral; Aged; Female; Humans; Male; Nausea; Ondansetron; Uremia; Vomiting

1995