ondansetron has been researched along with Thrombopenia in 4 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Excerpt | Relevance | Reference |
---|---|---|
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy." | 5.28 | Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992) |
"Ondansetron was a very effective antiemetic in the first weeks of treatment but its efficacy waned later on." | 2.67 | Phase I/II study of a short course of weekly cisplatin in patients with advanced solid tumours. ( de Boer-Dennert, M; Planting, AS; Stoter, G; van der Burg, ME; Verweij, J, 1993) |
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy." | 1.28 | Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Childs, AM | 1 |
Coates, AS | 2 |
Cox, KM | 1 |
Mainwaring, PN | 1 |
Planting, AS | 1 |
van der Burg, ME | 1 |
de Boer-Dennert, M | 1 |
Stoter, G | 1 |
Verweij, J | 1 |
Childs, A | 1 |
Cox, K | 1 |
Forsyth, C | 1 |
Joshua, DE | 1 |
McNeil, E | 1 |
Grygiel, JJ | 1 |
Castle, WM | 1 |
Cunningham, K | 1 |
Kanarek, BB | 1 |
1 trial available for ondansetron and Thrombopenia
Article | Year |
---|---|
Phase I/II study of a short course of weekly cisplatin in patients with advanced solid tumours.
Topics: Adult; Aged; Cisplatin; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged; | 1993 |
3 other studies available for ondansetron and Thrombopenia
Article | Year |
---|---|
Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.
Topics: Adult; Antineoplastic Agents; Emetics; Female; Humans; Male; Ondansetron; Renal Insufficiency; Throm | 1994 |
Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Female; Humans; Kid | 1992 |
Ondansetron is not associated with vascular adverse events, thrombocytopenia or renal failure.
Topics: Acute Kidney Injury; Cisplatin; Humans; Metoclopramide; Nausea; Neoplasms; Ondansetron; Thrombocytop | 1992 |