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ondansetron and Thrombopenia

ondansetron has been researched along with Thrombopenia in 4 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy."5.28Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992)
"Ondansetron was a very effective antiemetic in the first weeks of treatment but its efficacy waned later on."2.67Phase I/II study of a short course of weekly cisplatin in patients with advanced solid tumours. ( de Boer-Dennert, M; Planting, AS; Stoter, G; van der Burg, ME; Verweij, J, 1993)
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy."1.28Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Childs, AM1
Coates, AS2
Cox, KM1
Mainwaring, PN1
Planting, AS1
van der Burg, ME1
de Boer-Dennert, M1
Stoter, G1
Verweij, J1
Childs, A1
Cox, K1
Forsyth, C1
Joshua, DE1
McNeil, E1
Grygiel, JJ1
Castle, WM1
Cunningham, K1
Kanarek, BB1

Trials

1 trial available for ondansetron and Thrombopenia

ArticleYear
Phase I/II study of a short course of weekly cisplatin in patients with advanced solid tumours.
    British journal of cancer, 1993, Volume: 68, Issue:4

    Topics: Adult; Aged; Cisplatin; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged;

1993

Other Studies

3 other studies available for ondansetron and Thrombopenia

ArticleYear
Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:1

    Topics: Adult; Antineoplastic Agents; Emetics; Female; Humans; Male; Ondansetron; Renal Insufficiency; Throm

1994
Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Female; Humans; Kid

1992
Ondansetron is not associated with vascular adverse events, thrombocytopenia or renal failure.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:9

    Topics: Acute Kidney Injury; Cisplatin; Humans; Metoclopramide; Nausea; Neoplasms; Ondansetron; Thrombocytop

1992