ondansetron has been researched along with Testicular Neoplasms in 5 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-six consecutive patients, who were to be treated with cisplatin-based chemotherapy for testicular or bladder cancer, underwent a single-blind randomized study to compare the antiemetic therapies with dexamethasone (DEX)+ondansetron (OND) and DEX + alizapride (ALI)." | 9.07 | Dexamethasone plus ondansetron versus dexamethasone plus alizapride in the prevention of emesis induced by cisplatin-containing chemotherapies for urological cancers. ( Faustini, M; Mangiarotti, B; Nicolai, N; Piva, L; Pizzocaro, G; Salvioni, R, 1993) |
| " Patients who had suffered severe vomiting on carboplatin alone (23 patients with ovarian carcinoma) or in combination (two patients with testicular cancer) despite intensive antiemetic regimens were treated with ondansetron, given as 8 mg immediately prior to carboplatin followed by 8 mg orally, 8 hourly for 5 days." | 9.07 | Reduction of carboplatin induced emesis by ondansetron. ( Dickson, DS; Evans, BD; Harvey, VJ; Langley, GB; Mak, D; Mitchell, PL; Neave, LM, 1991) |
| "Thirty-six consecutive patients, who were to be treated with cisplatin-based chemotherapy for testicular or bladder cancer, underwent a single-blind randomized study to compare the antiemetic therapies with dexamethasone (DEX)+ondansetron (OND) and DEX + alizapride (ALI)." | 5.07 | Dexamethasone plus ondansetron versus dexamethasone plus alizapride in the prevention of emesis induced by cisplatin-containing chemotherapies for urological cancers. ( Faustini, M; Mangiarotti, B; Nicolai, N; Piva, L; Pizzocaro, G; Salvioni, R, 1993) |
| " Patients who had suffered severe vomiting on carboplatin alone (23 patients with ovarian carcinoma) or in combination (two patients with testicular cancer) despite intensive antiemetic regimens were treated with ondansetron, given as 8 mg immediately prior to carboplatin followed by 8 mg orally, 8 hourly for 5 days." | 5.07 | Reduction of carboplatin induced emesis by ondansetron. ( Dickson, DS; Evans, BD; Harvey, VJ; Langley, GB; Mak, D; Mitchell, PL; Neave, LM, 1991) |
| "Ondansetron hydrochloride is a selective serotonin subtype 3 (5HT3) receptor antagonist that has been shown to be an effective antiemetic in patients receiving cisplatin chemotherapy." | 2.67 | Phase III double-blind comparison of intravenous ondansetron and metoclopramide as antiemetic therapy for patients receiving multiple-day cisplatin-based chemotherapy. ( Einhorn, L; House, K; Nagy, C; Sledge, GW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicolai, N | 1 |
| Mangiarotti, B | 1 |
| Salvioni, R | 1 |
| Piva, L | 1 |
| Faustini, M | 1 |
| Pizzocaro, G | 1 |
| Khoo, VS | 1 |
| Rainford, K | 1 |
| Horwich, A | 1 |
| Dearnaley, DP | 1 |
| Sledge, GW | 1 |
| Einhorn, L | 1 |
| Nagy, C | 1 |
| House, K | 1 |
| Tong, D | 1 |
| Harvey, VJ | 1 |
| Evans, BD | 1 |
| Mitchell, PL | 1 |
| Mak, D | 1 |
| Neave, LM | 1 |
| Langley, GB | 1 |
| Dickson, DS | 1 |
4 trials available for ondansetron and Testicular Neoplasms
| Article | Year |
|---|---|
Dexamethasone plus ondansetron versus dexamethasone plus alizapride in the prevention of emesis induced by cisplatin-containing chemotherapies for urological cancers.
Topics: Adolescent; Adult; Aged; Antiemetics; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; H | 1993 |
The effect of antiemetics and reduced radiation fields on acute gastrointestinal morbidity of adjuvant radiotherapy in stage I seminoma of the testis: a randomized pilot study.
Topics: Acute Disease; Adult; Antiemetics; Diarrhea; Gastrointestinal Diseases; Humans; Lymphatic Metastasis | 1997 |
Phase III double-blind comparison of intravenous ondansetron and metoclopramide as antiemetic therapy for patients receiving multiple-day cisplatin-based chemotherapy.
Topics: Adolescent; Adult; Cisplatin; Double-Blind Method; Humans; Injections, Intravenous; Male; Metoclopra | 1992 |
Reduction of carboplatin induced emesis by ondansetron.
Topics: Antiemetics; Carboplatin; Dysgerminoma; Female; Humans; Imidazoles; Male; Middle Aged; Nausea; Ondan | 1991 |
1 other study available for ondansetron and Testicular Neoplasms
| Article | Year |
|---|---|
Ondansetron and radiotherapy.
Topics: Adult; Antiemetics; Dysgerminoma; Humans; Imidazoles; Male; Middle Aged; Ondansetron; Radiotherapy; | 1992 |