Page last updated: 2024-11-01

ondansetron and Stomach Ulcer

ondansetron has been researched along with Stomach Ulcer in 9 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
"We used the murine re-fed indomethacin (IND) experimental ulcer model."8.31Gastroparesis Worsens Indomethacin-Induced Gastric Antral Ulcers by Bile Reflux via Activation of 5-HT ( Akiba, Y; Kaunitz, JD; Satoh, H; Urushidani, T, 2023)
"Fluvoxamine with different administration routes and ondansetron monotherapy before stress reduce the occurrence of gastric ulcers, while the combination drugs did not increase the protective effect of the gastric mucosa."8.02Gastroprotective effect of fluvoxamine and ondansetron on stress-induced gastric ulcers in mice. ( Agung Dewaandika, W; Andarsari, MR; Aryani, T; Oktavia Hanaratri, E; Rahmadi, M; Su'aida, N; Yustisari, P, 2021)
"The effect of central administration of ondansetron, a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist on gastric secretion and gastric cytoprotection was evaluated using four different models of gastric ulcers and cysteamine induced duodenal ulcer."7.75Effect of central administration of ondansetron, a 5-hydroxytryptamine-3 receptor antagonist on gastric and duodenal ulcers. ( Asad, M; Dhamanigi, SS; Prasad, VS; Ramesh, ST, 2009)
"We used the murine re-fed indomethacin (IND) experimental ulcer model."4.31Gastroparesis Worsens Indomethacin-Induced Gastric Antral Ulcers by Bile Reflux via Activation of 5-HT ( Akiba, Y; Kaunitz, JD; Satoh, H; Urushidani, T, 2023)
"Fluvoxamine with different administration routes and ondansetron monotherapy before stress reduce the occurrence of gastric ulcers, while the combination drugs did not increase the protective effect of the gastric mucosa."4.02Gastroprotective effect of fluvoxamine and ondansetron on stress-induced gastric ulcers in mice. ( Agung Dewaandika, W; Andarsari, MR; Aryani, T; Oktavia Hanaratri, E; Rahmadi, M; Su'aida, N; Yustisari, P, 2021)
"The effect of central administration of ondansetron, a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist on gastric secretion and gastric cytoprotection was evaluated using four different models of gastric ulcers and cysteamine induced duodenal ulcer."3.75Effect of central administration of ondansetron, a 5-hydroxytryptamine-3 receptor antagonist on gastric and duodenal ulcers. ( Asad, M; Dhamanigi, SS; Prasad, VS; Ramesh, ST, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Satoh, H1
Akiba, Y1
Urushidani, T1
Kaunitz, JD1
Rahmadi, M1
Su'aida, N1
Yustisari, P1
Agung Dewaandika, W1
Oktavia Hanaratri, E1
Andarsari, MR1
Aryani, T1
Burns, RA1
Schmidt, SM1
Ramesh, ST1
Asad, M1
Dhamanigi, SS1
Prasad, VS1
Debnath, S1
Biswas, D1
Ray, K1
Guha, D1
Ogle, CW2
Hui, SC2
Cho, CH1
Koo, MW1
Ko, JK1
Takeuchi, K1
Kato, S1
Hirata, T1
Nishiwaki, H1
Qiu, BS1
Li, KM1

Other Studies

9 other studies available for ondansetron and Stomach Ulcer

ArticleYear
Gastroparesis Worsens Indomethacin-Induced Gastric Antral Ulcers by Bile Reflux via Activation of 5-HT
    Digestive diseases and sciences, 2023, Volume: 68, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Apomorphine; Atropine; Bile Reflux; C

2023
Gastroprotective effect of fluvoxamine and ondansetron on stress-induced gastric ulcers in mice.
    Journal of basic and clinical physiology and pharmacology, 2021, Jun-25, Volume: 32, Issue:4

    Topics: Animals; Fluvoxamine; Gastric Mucosa; Mice; Ondansetron; Pharmaceutical Preparations; Rats, Wistar;

2021
Portal venous gas emboli after accidental ingestion of concentrated hydrogen peroxide.
    The Journal of emergency medicine, 2013, Volume: 45, Issue:3

    Topics: Abdominal Pain; Antiemetics; Child; Embolism, Air; Fluid Therapy; Hematemesis; Humans; Hydrogen Pero

2013
Effect of central administration of ondansetron, a 5-hydroxytryptamine-3 receptor antagonist on gastric and duodenal ulcers.
    Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Ac

2009
Moringa oleifera induced potentiation of serotonin release by 5-HT(3) receptors in experimental ulcer model.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jan-15, Volume: 18, Issue:2-3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Enterochromaffin Cells; Female; Male; M

2011
The influence of peripheral or central administration of ondansetron on stress-induced gastric ulceration in rats.
    Experientia, 1995, Aug-16, Volume: 51, Issue:8

    Topics: Animals; Cell Degranulation; Cold Temperature; Female; Injections, Intraventricular; Injections, Sub

1995
Modulatory role of 5-HT3 receptors in gastric function and ethanol-induced mucosal damage in rat stomachs.
    Pharmacology, 1994, Volume: 49, Issue:3

    Topics: Animals; Blood Flow Velocity; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Mucos

1994
Gastric motility and mucosal ulcerogenic responses induced by prokinetic drugs in rats under prostaglandin-deficient conditions.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:2

    Topics: Animals; Cisapride; Dose-Response Relationship, Drug; Gastric Acid; Gastric Emptying; Gastric Mucosa

1997
5-Hydroxytryptamine3-receptor blockade protects against gastric mucosal damage in rats.
    Acta physiologica Hungarica, 1992, Volume: 80, Issue:1-4

    Topics: Animals; Cold Temperature; Cyproheptadine; Dose-Response Relationship, Drug; Ethanol; Female; Gastri

1992