ondansetron has been researched along with Spinal Cord Injuries in 3 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic neuropathic pain is a frequent, serious outcome of spinal cord injury (SCI) that is highly refractory to treatment." | 1.35 | Blockade of the 5-HT3 receptor for days causes sustained relief from mechanical allodynia following spinal cord injury. ( Chen, Y; Oatway, MA; Weaver, LC, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 2 |
| Oatway, MA | 2 |
| Weaver, LC | 2 |
| Lacassie, HJ | 1 |
| Schultz, JR | 1 |
| Cummings, TJ | 1 |
| Morris, R | 1 |
| Trasti, SL | 1 |
| Reynolds, JD | 1 |
3 other studies available for ondansetron and Spinal Cord Injuries
| Article | Year |
|---|---|
Blockade of the 5-HT3 receptor for days causes sustained relief from mechanical allodynia following spinal cord injury.
Topics: Animals; Infusions, Intravenous; Injections, Spinal; Male; Neuralgia; Ondansetron; Rats; Rats, Wista | 2009 |
The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury.
Topics: 5,6-Dihydroxytryptamine; Animals; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Dr | 2004 |
Behavioural testing and histological assessments of rabbit spinal cord following intrathecal administration of ondansetron.
Topics: Animals; Arousal; Behavior, Animal; Drug Combinations; Female; Injections, Spinal; Morphine; Motor A | 2006 |