ondansetron has been researched along with Sleep Apnea, Obstructive in 5 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Villedieu, E | 1 |
| Robinson, W | 1 |
| Shales, C | 1 |
| Roberts, C | 1 |
| Al Sayegh, R | 1 |
| Ellison, PR | 1 |
| Sedeek, K | 1 |
| Carr, MM | 1 |
| Prasad, B | 1 |
| Radulovacki, M | 2 |
| Olopade, C | 1 |
| Herdegen, JJ | 1 |
| Logan, T | 1 |
| Carley, DW | 1 |
| Stradling, J | 1 |
| Smith, D | 1 |
| Carley, D | 1 |
| Fenik, P | 1 |
| Ogawa, H | 1 |
| Veasey, SC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056] | Phase 4 | 200 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ondansetron and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Prospective trial of efficacy and safety of ondansetron and fluoxetine in patients with obstructive sleep apnea syndrome.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine | 2010 |
Effect of ondansetron on moderate obstructive sleep apnoea, a single night, placebo-controlled trial.
Topics: Drug Administration Schedule; Female; Humans; Male; Middle Aged; Ondansetron; Serotonin Antagonists; | 2003 |
3 other studies available for ondansetron and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Suspected Obstructive Sleep Apnea Successfully Treated with Ondansetron in a Pug.
Topics: Airway Obstruction; Animals; Craniosynostoses; Dog Diseases; Dogs; Ondansetron; Sleep Apnea, Obstruc | 2022 |
How Pediatric Anesthesiologists Manage Children with OSA Undergoing Tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Airway Extubation; Analgesics; Anesthesiology; Anesthetics; Anti-Infla | 2020 |
Hypoglossal nerve response to 5-HT3 drugs injected into the XII nucleus and vena cava in the rat.
Topics: Animals; Biguanides; Hypoglossal Nerve; Injections, Intravenous; Male; Microinjections; Motor Neuron | 2001 |