ondansetron has been researched along with Postoperative Complications in 203 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postoperative nausea and vomiting (PONV) is still a common perioperative complication and ondansetron has proved to be an effective antiemetic substance in its prevention." | 10.18 | [Prevention of postoperative nausea and vomiting with single and repeat administration of ondansetron--review of the literature on different administration forms]. ( Buhre, W; Kazmaier, S; Mühr, C; Neumann, P; Saur, P, 1996) |
| "Ondansetron is a 5-HT3 receptor antagonist which is effective and well tolerated as an antiemetic for emesis induced by cancer chemotherapy and radiation therapy, and in the prevention and treatment of postoperative nausea and vomiting." | 10.17 | Clinical pharmacology of ondansetron in postoperative nausea and vomiting. ( Baber, N; Frazer, NM; Palmer, JL; Pritchard, JF, 1992) |
| "5 mg IV with ondansetron 8 mg IV for the treatment of nausea and vomiting." | 9.69 | Droperidol versus ondansetron for nausea treatment within the emergency department. ( Clemensen, E; Lau, GT; Philpott, L, 2023) |
| "To investigate the controlling efficacy of ondasetron and haloperidol in regard to the postcardiotomy delirium." | 9.16 | Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study. ( Daskalopoulos, ME; Gogaki, E; Papaliagkas, V; Parisis, C; Sataitidis, I; Tagarakis, GI; Tsagalas, I; Tsilimingas, NB; Tsolaki, F; Tsolaki, M; Voucharas, C, 2012) |
| " reduces the severity of pruritus and the use of rescue anti-pruritic medication, and improves satisfaction but does not reduce the overall incidence of pruritus in women who have received subarachnoid morphine 150 microg compared to ondansetron 8 mg i." | 9.14 | Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron. ( Carey, M; Choroszczak, P; Immani, S; Ojo, R; Tan, T, 2010) |
| "Of the 380 patients evaluated, significantly fewer ondansetron 4 mg treated patients (89/189; 47%) experienced postoperative nausea and/or vomiting compared with metoclopramide treated patients (115/ 191; 60%) during the study period (p = 0." | 9.13 | Ondansetron vs. metoclopramide for the prevention of nausea and vomiting after gynecologic surgery. ( Diregpoke, S; Krobbuaban, B; Pitakpol, S, 2008) |
| " We evaluated the effects of oral ondansetron disintegrating tablets (ODT) on the incidence of at-home emesis in children undergoing tonsillectomy with and without adenoidectomy and with and without bilateral myringotomy and tube insertion." | 9.13 | The effects of oral ondansetron disintegrating tablets for prevention of at-home emesis in pediatric patients after ear-nose-throat surgery. ( Boretsky, KR; Davis, PJ; Fedel, GM; Fertal, KM; Gurnaney, H; Hoffmann, PC; Ingram, MD; Woelfel, SK; Young, MC, 2008) |
| "We compared the efficacy of inhaled isopropyl alcohol (IPA) with ondansetron for the control of postoperative nausea and vomiting (PONV) during a 24-hour period in 100 ASA class I-III women undergoing laparoscopic surgery." | 9.12 | A comparative analysis of isopropyl alcohol and ondansetron in the treatment of postoperative nausea and vomiting from the hospital setting to the home. ( Cotton, JW; Hood, RR; Pellegrini, JE; Rowell, LR, 2007) |
| "In this study, the efficacy and safety of intravenous administration of droperidol followed by oral use of dimenhydrinate did not differ from that of intravenous followed by oral use of ondansetron in children undergoing strabismus surgery." | 9.10 | Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery. ( Bussières, JF; Caron, E; Jacob, JL; Lebel, D; Lortie, L; Mathews, S; Milot, J; Moride, Y, 2003) |
| "In this prospective, randomized, double-blinded study, we compared the prophylactic efficacy of nalbuphine and ondansetron for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 9.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "To assess the efficacy and safety of intravenous ondansetron (4 mg) for the prevention of nausea and vomiting after middle ear surgery under local anesthesia." | 9.09 | Efficacy of ondansetron for prevention of postoperative nausea and vomiting after outpatient ear surgery under local anesthesia. ( Ku, PK; Lo, P; Tong, MC; van Hasselt, CA, 2000) |
| "This prospective, randomized, placebo-controlled, double-blind study was designed to evaluate the efficacy of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting (PONV) after elective craniotomy in adult patients." | 9.09 | Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy. ( Bhatia, A; Dash, HH; Kathirvel, S; Prakash, A; Shenoy, S; Subramaniam, B, 2001) |
| "A prospective double-blind study was conducted to compare the anti-emetic efficacy of ondansetron and droperidol in preventing postoperative emesis following strabismus surgery." | 9.08 | A double-blind randomized prospective study comparing ondansetron with droperidol in the prevention of emesis following strabismus surgery. ( Davis, A; Krige, S; Moyes, D, 1995) |
| "Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV)." | 9.08 | Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery. ( Altrock, K; Diefenbach, C; Grond, S; Lehmann, KA; Lynch, J, 1995) |
| "To compare the effectiveness of ondansetron with droperidol in preventing postoperative emesis in children after strabismus repair." | 9.08 | Prevention of emesis after strabismus repair in children: a prospective, double-blinded, randomized comparison of droperidol versus ondansetron. ( Griswold, JD; Lee, A; Litman, RS; Marshall, C; Voisine, R; Wu, CL, 1995) |
| "This randomized, double-blind, multicentre, parallel-group study compared the efficacy and safety of an intravenous dose of ondansetron 4 mg for the prevention of postoperative nausea and vomiting (PONV) with metoclopramide 10 mg and placebo in patients undergoing major gynaecological surgery." | 9.08 | [Intravenous administration of ondansetron vs. metoclopramide for the prophylaxis of postoperative nausea and vomiting]. ( Rust, M, 1995) |
| "We have compared the efficacy of ondansetron, metoclopramide, droperidol and placebo in the prevention of postoperative nausea and vomiting in 118 day stay patients undergoing laparoscopic gynaecological procedures." | 9.08 | Prevention of nausea and vomiting after day case gynaecological laparoscopy. A comparison of ondansetron, droperidol, metoclopramide and placebo. ( McKay, AC; Mirakhur, RK; Paxton, LD, 1995) |
| " Effective prophylaxis for postoperative nausea and vomiting can be achieved in adults with lower doses of ondansetron, a 5-hydroxytryptamine subtype 3 receptor antagonist, compared with chemotherapy-induced emesis." | 9.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "In a randomised, placebo-controlled trial we have compared the efficacy of ondansetron and droperidol in reducing postoperative nausea and vomiting associated with patient-controlled analgesia after orthopaedic surgery." | 9.08 | Comparison of ondansetron and droperidol in reducing postoperative nausea and vomiting associated with patient-controlled analgesia. ( Alexander, R; Jones, RM; Lovell, AT; Seingry, D, 1995) |
| "The aim of this study was to compare the efficacy and safety of ondansetron plus droperidol with each drug alone or placebo in the prevention of postoperative nausea and vomiting (PONV)." | 9.08 | Combination of ondansetron and droperidol in the prophylaxis of postoperative nausea and vomiting. ( Carrascosa, F; García-Pedrajas, F; Iribarren, MJ; Lopez, L; Pueyo, FJ; Saez, A, 1996) |
| " Patients received one of four regimens for the prevention of postoperative nausea and vomiting (PONV): ondansetron 4 mg (n = 25), dexamethasone 8 mg (n = 25), ondansetron with dexamethasone (4 mg and 8 mg, respectively, n = 25) or placebo (saline, n = 25) There were no differences in background factors or factors related to operation and anaesthesia, morphine consumption, pain or side effects between groups." | 9.08 | Combination of ondansetron and dexamethasone in the prophylaxis of postoperative nausea and vomiting. ( Busto, N; Carrascosa, F; López-Olaondo, L; Monedero, P; Pueyo, FJ; Sáez, A, 1996) |
| " This randomized, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of ondansetron in the control of established postoperative emesis in outpatients aged 2-12 yr." | 9.08 | Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group. ( Creed, M; Ginsberg, B; Grunwald, Z; Kaye, R; Khalil, S; Lawhorn, CD; Otto, A; Prillaman, BA; Rodarte, A; Weinstein, M; Weldon, BC; Wheeler, M, 1996) |
| "The efficacy of ondansetron 4 mg and 8 mg was compared with placebo in the reduction of postoperative nausea, retching and vomiting (PONV) after middle ear surgery during general anaesthesia, in 75 patients, in a double-blind and randomized study." | 9.08 | Effect of ondansetron on nausea and vomiting after middle ear surgery during general anaesthesia. ( Honkavaara, P, 1996) |
| "This study has compared the incidences of nausea, vomiting and headache after ondansetron 0." | 9.08 | Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. ( van den Berg, AA, 1996) |
| "The new antiemetic ondansetron is effective for the prophylaxis and treatment of postoperative nausea and vomiting (PONV), but has been subject to limited comparative evaluation in surgical inpatients." | 9.08 | Single-dose prophylaxis for postoperative nausea and vomiting after major abdominal surgery: ondansetron versus droperidol. ( Evans, SF; Paech, MJ; Pavy, TJ, 1995) |
| "The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery." | 9.08 | Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996) |
| "To compare the antimetic efficacy of prophylactic ondansetron, metoclopramide, and placebo for prevention of postoperative vomiting in pediatric tonsillectomy or adenotonsillectomy patients." | 9.08 | Prospective, randomized, double-blind, placebo-controlled comparison of metoclopramide and ondansetron for prevention of posttonsillectomy or adenotonsillectomy emesis. ( Bohnsack, LE; Bostrom, BC; Seay, RE; Stene, FN; Young, LA, 1996) |
| "Propofol administered to induce and maintain anesthesia is more effective than ondansetron (with thiopental-isoflurane anesthesia) in preventing postoperative vomiting and is associated with fewer requests for rescue antiemetic and sedation in the early phase of recovery." | 9.08 | Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting. ( Gan, TJ; Ginsberg, B; Glass, PS; Grant, AP, 1996) |
| "To determine (1) the efficacy and safety of ondansetron in the prevention of postoperative nausea and vomiting (PONV) in male outpatients; (2) prognostic factors for PONV in male outpatients; and (3) patients' perceptions of the debilitating effects of PONV in the ambulatory surgery setting." | 9.08 | Ondansetron prevents postoperative emesis in male outpatients. S3A-379 Study Group. ( Cox, F; Joslyn, AF; Khalil, SN; Kovac, AL; Pearman, MH; Prillaman, BA; Scuderi, PE, 1996) |
| "The hypothesis that the addition of dexamethasone to the propofolondansetron combination would significantly reduce postoperative nausea and vomiting (PONV) was not confirmed." | 9.08 | Effect of propofol for induction and ondansetron with or without dexamethasone for the prevention of nausea and vomiting after major gynecologic surgery. ( Hamilton, DL; McKenzie, R; Riley, TJ; Tantisira, B, 1997) |
| "To assess the efficacy of 4 mg of intravenous ondansetron versus placebo for the prevention of postoperative nausea and vomiting (PONV) in cholecystectomy, a type of surgery that is highly emetic." | 9.08 | [Efficacy of ondansetron in the prevention of nausea and vomiting after laparoscopic cholecystectomy]. ( Cabrera, JC; Castaño, J; Castillo, J; Escolano, F; Matute, E; Santiveri, X, 1997) |
| "A double-blind, randomised, placebo-controlled trial was conducted to compare the efficacy of metoclopramide with the 5-HT3 antagonist, ondansetron, for the prevention of postoperative emesis in children undergoing elective strabismus surgery." | 9.08 | Efficacy of ondansetron and metoclopramide for preventing postoperative emesis following strabismus surgery in children. ( Mandal, NG; Shende, D, 1997) |
| "To compare the efficacy of oral ondansetron with oral metoclopramide for the prevention of postoperative vomiting and nausea in children undergoing strabismus surgery." | 9.08 | [Does oral ondansetron reduce the incidence of nausea and vomiting after surgery for strabismus in children?]. ( Amraoui, A; Benaguida, M; el Harrar, N; Idali, B; Laouissi, F; Mjahed, K, 1996) |
| "To compare the efficacy in the treatment of post-operative nausea and/or vomiting (PONV), 75 patients undergoing gynaecological procedures under general anaesthesia using N2O/enflurane who suffered from PONV in the first hour after surgery were randomly allocated to three groups containing 25 patients each to receive either alizapride 100 mg, droperidol 1 mg or ondansetron 8 mg (i." | 9.08 | Double-blind comparison of alizapride, droperidol and ondansetron in the treatment of post-operative nausea. ( Bovill, JG; de Bont, LE; el-Mofty, M; Samhan, YM; Stienstra, R, 1997) |
| "In a randomised, double-blind study, we have compared the incidence of postoperative nausea and vomitting in 124 patients undergoing major lower limb orthopaedic surgery following oral premedication with temazapam and ondansetron 8 mg, metoclopramide 10 mg or placebo." | 9.08 | Comparison of ondansetron, metoclopramide and placebo as premedicants to reduce nausea and vomiting after major surgery. ( Alexander, R; Fennelly, M, 1997) |
| " This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model." | 9.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| "In this study the antiemetic effects of droperidol, ondansetron and their combination were evaluated in 160 ASA Grade I and II children undergoing surgery for strabismus, who were randomly assigned to one of four groups: Group D received droperidol 75 micrograms kg-1, group O ondansetron 0." | 9.08 | Ondansetron, droperidol and their combination for the prevention of post-operative vomiting in children. ( Braun, U; Klockgether-Radke, A; Mühlendyck, H; Neumann, P; Neumann, S, 1997) |
| "Intravenous dolasetron mesilate has shown efficacy in the prevention of postoperative nausea and vomiting (PONV) when administered as a single dose prior to emergence from anesthesia." | 9.08 | Intravenous dolasetron and ondansetron in prevention of postoperative nausea and vomiting: a multicenter, double-blind, placebo-controlled study. ( Brown, R; Clergue, F; Feiss, P; Hahne, W; Korttila, K; Leeser, J; Nave, S; Olthoff, D; Payeur-Michel, C; Wessel, P, 1997) |
| "To compare the prophylactic administration of ondansetron with droperidol or placebo to determine its effectiveness in reducing postoperative nausea and vomiting after middle ear procedures." | 9.08 | Ondansetron versus droperidol or placebo when given prophylactically for the prevention of postoperative nausea and vomiting in patients undergoing middle ear procedures. ( Fluter, E; Jellish, WS; Leonetti, JP; Thalji, Z, 1997) |
| "1 mg/kg to 4 mg intravenously) compared with placebo in the prevention of postoperative vomiting in 429 ASA status I-III children 1-12 yr old undergoing outpatient surgery under nitrous oxide- and halothane-based general anesthesia." | 9.08 | Single-dose ondansetron prevents postoperative vomiting in pediatric outpatients. ( Cohen, IT; Colingo, K; Creed, MR; Davis, PJ; Donlon, JV; Ferrari, LR; Haberkern, CM; Hannallah, RS; McGowan, FX; Orr, RJ; Parasuraman, TV; Patel, RI; Prillaman, BA; Rimar, S, 1997) |
| "To investigate the incidence of postoperative nausea and vomiting (PONV) depending on the administration time of ondansetron." | 9.08 | [Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients]. ( Kainzwaldner, A; Ploner, F, 1997) |
| "To compare the efficacy of ondansetron, droperidol, or metoclopramide with placebo in preventing postoperative vomiting following strabismus surgery." | 9.08 | A randomized, double-blind, placebo controlled comparison of droperidol, ondansetron, and metoclopramide for the prevention of vomiting following outpatient strabismus surgery in children. ( Elliott, WG; James, RL; Mims, G; Scuderi, PE; Weaver, RG; Weeks, DB, 1997) |
| " After experiencing at least one nausea and/or one emetic episode in the 6 h after recovery from anaesthesia, patients received either ondansetron 4 mg i." | 9.08 | Ondansetron compared with metoclopramide in the treatment of established postoperative nausea and vomiting. The French Ondansetron Study Group. ( Clyti, N; Conseiller, C; Diemunsch, P; Mamet, JP, 1997) |
| "The proportion of patients with nausea was 48%, 50% and 67% in the ondansetron, droperidol and placebo groups, respectively; with a significant difference when both ondansetron (P=0." | 9.08 | Comparison of ondansetron and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women. A randomised, double-blind, placebo-controlled trial. ( Alahuhta, S; Koivuranta, M; Läärä, E; Ranta, P; Ravaska, P, 1997) |
| "Low-dose ondansetron plus dexamethasone is an effective prophylactic antiemetic combination for children undergoing strabismus surgery." | 9.08 | Low-dose ondansetron with dexamethasone more effectively decreases vomiting after strabismus surgery in children than does high-dose ondansetron. ( Rhine, EJ; Splinter, WM, 1998) |
| "Ondansetron 4 mg was compared with metoclopramide 10 mg for prevention of post-operative nausea and emesis in in-patients undergoing major gynaecological surgery in this double-blind, randomized, placebo-controlled, multicentre study." | 9.08 | International, multicentre, placebo-controlled study to evaluate the effectiveness of ondansetron vs. metoclopramide in the prevention of post-operative nausea and vomiting. ( Aune, H; Cohen, LA; Feiss, P; Hanson, A; Hasselstrøm, L; Maltby, JR; Morris, RW; Rocke, DA; Rozenberg, B; Rust, M, 1998) |
| " bolus dose of ondansetron 4 mg were evaluated in the prevention of postoperative nausea and vomiting (PONV), which remains one of the most unpleasant side effects experienced by patients postoperatively." | 9.08 | Single i.v. bolus dose of ondansetron in the prevention of postoperative nausea and emesis. ( De Guchteneere, E; Hendrickx, P; Levarlet, M; Moens, P, 1997) |
| "To investigate the hypothesis that the combination of ondansetron and droperidol would be more effective than droperidol alone in reducing nausea and vomiting." | 9.08 | Droperidol-ondansetron combination versus droperidol alone for postoperative control of emesis after total abdominal hysterectomy. ( Hamilton, DL; McKenzie, R; Riley, TJ; Trantisira, BR, 1998) |
| "We have compared the effects of ondansetron and perphenazine on vomiting after tonsillectomy in 216 healthy children, aged 2-12 yr." | 9.08 | Prophylaxis for vomiting by children after tonsillectomy: ondansetron compared with perphenazine. ( Rhine, EJ; Splinter, WM, 1998) |
| "This study compares the preoperative administration of ondansetron with that of droperidol or saline solution for the prevention of nausea and vomiting in otologic surgery patients." | 9.08 | Ondansetron versus droperidol or placebo to prevent nausea and vomiting after otologic surgery. ( Fluder, E; Jellish, WS; Leonetti, JP; Thalji, Z, 1998) |
| "To determine the dose-response relationship of ondansetron in preventing postoperative nausea and vomiting (PONV) in women undergoing elective surgery." | 9.08 | A randomized, double-blind, dose-response study of ondansetron in the prevention of postoperative nausea and vomiting. ( Chang, Y; Conant, JA; Connors, PM; Dershwitz, M; Rosow, CE, 1998) |
| "The efficacy and safety of ondansetron in preventing postoperative nausea and vomiting following minor oral surgery was evaluated in a prospective randomized double-blind study." | 9.07 | Ondansetron for prevention of postoperative nausea and vomiting following minor oral surgery: a double-blind randomized study. ( Campbell, RC; Chow, J; Hui, E; Lueveswanij, S; Rodrigo, MR; Tong, CK, 1994) |
| "25 mg droperidol in preventing postoperative vomiting." | 9.07 | [Ondansetron as prophylaxis for postoperative nausea and vomiting. A prospective randomized double-blind comparative study with droperidol]. ( Alon, E; Atanassoff, PG; Biro, P; Lenzlinger, PM, 1994) |
| "Ondansetron is more effective than a placebo in treating postoperative nausea and vomiting (PONV), but it has not been proved to be superior to established antiemetics for prophylaxis or therapy." | 9.07 | [Ondansetron versus droperidol. Postoperative treatment against nausea and vomiting. Comparison of action, adverse effects and acceptance by gynecologic inpatients]. ( Heim, C; Listyo, R; Münzer, T, 1994) |
| "The purpose of this double-blind, randomized study was to compare the effectiveness of ondansetron plus saline versus ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting." | 9.07 | Comparison of ondansetron with ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting. ( Abdelhady, H; Karambelkar, DJ; McKenzie, R; Riley, TJ; Tantisira, B, 1994) |
| "This prospective, randomized, placebo-controlled, double-blinded study evaluated the antiemetic efficacy of ondansetron and metoclopramide in 90 ASA physical status I or II children, 2-17 yr of age, undergoing strabismus repair." | 9.07 | Ondansetron reduces the incidence and severity of poststrabismus repair vomiting in children. ( Corddry, DH; Kettrick, RG; Martin, TM; Rose, JB; Zagnoev, M, 1994) |
| "We performed a double-blind, randomized, placebo-controlled trial to investigate the efficacy and safety of ondansetron in preventing vomiting after tonsillectomy with or without adenoidectomy in children." | 9.07 | Ondansetron decreases emesis after tonsillectomy in children. ( Catanzaro, FA; Litman, RS; Wu, CL, 1994) |
| "In two placebo-controlled, double-blind, multicentre studies, the efficacy and safety of single oral doses of ondansetron 4 mg, 8 mg and 16 mg were evaluated for the prevention of postoperative nausea and vomiting in female inpatients." | 9.07 | Single oral dose ondansetron in the prevention of postoperative nausea and emesis. The European and US Study Groups. ( Cohen, LA; Rust, M, 1994) |
| "We have compared the efficacy of ondansetron with droperidol and saline in the prevention of postoperative nausea and vomiting (PONV) in 120 ASA I and II patients undergoing hip and knee replacements and femoral resections." | 9.07 | Double-blind comparison of ondansetron, droperidol and saline in the prevention of postoperative nausea and vomiting. ( Collis, R; Gan, TJ; Hetreed, M, 1994) |
| "The effect of a single intravenous dose of ondansetron in preventing postoperative nausea and emesis (retching and vomiting) (PONV) was investigated in a randomized, double-blind, placebo-controlled, multicentre, international study." | 9.07 | A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. ( Abrahamsson, J; Briggs, L; Forrler, M; Hellstern, K; Helmers, JH; Moodley, J; Soni, J, 1993) |
| " Patients were stratified by gender and received, in a randomized, double-blind manner, 1, 4, or 8 mg ondansetron or placebo in response to nausea and/or vomiting postoperatively." | 9.07 | Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron. ( Apfelbaum, J; Claybon, L; DuPen, S; Leslie, J; Mingus, M; Scuderi, P; Sharifi-Azad, S; Sung, YF; Talke, P; Wetchler, B, 1993) |
| "Data from the 544 women showed that all doses of intravenous ondansetron tested (1, 4, and 8 mg) were significantly more effective (62%, 76%, and 77%, respectively) than placebo (46%) in reducing the incidence of emesis following surgery until 24 h after recovery room entry." | 9.07 | Comparison of ondansetron versus placebo to prevent postoperative nausea and vomiting in women undergoing ambulatory gynecologic surgery. ( Angel, J; Duncalf, D; Gratz, I; Joslyn, A; Kovac, A; McKenzie, R; McLeskey, C; O'Connor, T; Tolpin, E, 1993) |
| "The efficacy and safety of ondansetron in preventing postoperative nausea and vomiting following major gynaecological surgery was evaluated in this multicentre, double-blind study." | 9.07 | The effect of oral ondansetron in the prevention of postoperative nausea and vomiting after major gynaecological surgery performed under general anaesthesia. ( Conseiller, C; Dupeyron, JP; Gribomont, B; Hemmingsen, C; Kaplan, LA; Levarlet, M; Pedersen, FM; Schoeffler, P, 1993) |
| "The effect of three times daily oral ondansetron in preventing postoperative nausea and vomiting was investigated in two randomized, double-blind, placebo-controlled, multi-centre studies." | 9.07 | Oral ondansetron in the prevention of postoperative nausea and vomiting. ( Helmers, JH, 1992) |
| "The efficacy of ondansetron, a selective 5-HT3 receptor antagonist, in preventing postoperative nausea and vomiting in surgical patients was studied." | 9.07 | Ondansetron is effective in decreasing postoperative nausea and vomiting. ( Dershwitz, M; Di Biase, PM; Joslyn, AF; Rosow, CE; Sanderson, PE, 1992) |
| "In a placebo-controlled, double-blind study, we have compared the efficacy of ondansetron 16 mg, 8 mg and 1 mg administered 8-hourly for prevention of postoperative nausea and vomiting." | 9.07 | Efficacy of orally administered ondansetron in the prevention of postoperative nausea and vomiting: a dose ranging study. ( Haigh, CG; Kenny, GN; Leeser, J; Lip, H; Oates, JD; Onsrud, M; Rowbotham, DJ; Rust, M; Saur, P, 1992) |
| "The safety and efficacy of ondansetron were evaluated in the treatment of postoperative nausea and vomiting." | 9.07 | Ondansetron in the treatment of postoperative nausea and vomiting in ambulatory outpatients: a dose-comparative, stratified, multicentre study. ( Apfelbaum, J; Clayborn, L; Du Pen, S; Leslie, J; Mingus, M; Scuderi, P; Sharifi-Azad, S; Sung, YF; Talke, P; Wetchler, B, 1992) |
| "The effect of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting was investigated in a randomized, double-blind, placebo-controlled study of 84 patients undergoing gynecologic operation and receiving the same general anesthetic." | 9.07 | Prevention of postoperative nausea and vomiting using ondansetron, a new, selective, 5-HT3 receptor antagonist. ( Leeser, J; Lip, H, 1991) |
| "To assess the efficacy of ondansetron and the incidence of headache when used as prophylaxis for postoperative vomiting." | 8.80 | Ondansetron in the prophylaxis of postoperative vomiting: a meta-analysis. ( Canosa, LG; Figueredo, ED, 1998) |
| "For the usual doses recommended for postoperative emesis, there was equivalent effectiveness of ondansetron whether administered as prophylaxis or as a treatment of established vomiting." | 8.80 | Prevention or treatment of postoperative vomiting using ondansetron? A mathematical assessment. ( Canosa, LG; Figueredo, E, 1999) |
| "The clinical development of ondansetron for the prevention and treatment of postoperative nausea and vomiting has been progressing for 5 years, and continues as new directions of research are being addressed." | 8.79 | Ondansetron, clinical development for postoperative nausea and vomiting: current studies and future directions. ( Joslyn, AF, 1994) |
| "To test the evidence for a dose-response with ondansetron for treatment of postoperative nausea and vomiting and to establish whether differences in efficacy between doses are of clinical relevance." | 8.79 | A quantitative systematic review of ondansetron in treatment of established postoperative nausea and vomiting. ( McQuay, HJ; Moore, RA; Reynolds, DJ; Tramèr, MR, 1997) |
| "The authors reviewed efficacy and safety data for ondansetron for preventing postoperative nausea and vomiting (PONV)." | 8.79 | Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials. ( McQuay, HJ; Moore, RA; Reynolds, DJ; Tramèr, MR, 1997) |
| "Ondansetron is a selective 5-HT3 receptor antagonist which has previously been reported in the Journal to be a promising new agent for use as prophylaxis against nausea and vomiting caused by chemotherapy and radiotherapy." | 8.78 | Ondansetron. An update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting. ( Markham, A; Sorkin, EM, 1993) |
| "An international clinical trial programme has been established to assess the efficacy and safety of ondansetron in the prevention and treatment of postoperative nausea and vomiting." | 8.78 | The clinical development of ondansetron for use in the prevention and treatment of postoperative nausea and vomiting. ( Haigh, CG; Hellstern, K; Inall, FC; Isal, JP; Joslyn, AF; Kanarek, BK; Kaplan, LA; Povey, PM, 1992) |
| "To evaluate the effect of the 5-HT3-receptor antagonist ondansetron in patients with postcardiotomy delirium." | 7.70 | The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium. ( Akpinar, B; Bayindir, O; Can, E; Demiroğlu, C; Güden, M; Sönmez, B, 2000) |
| "To determine how many patients were deprived of treatment by being given placebo as comparator in trials of ondansetron for postoperative nausea and vomiting." | 7.69 | Denial of effective treatment and poor quality of clinical information in placebo controlled trials of ondansetron for postoperative nausea and vomiting: a review of published trials. ( Aspinall, RL; Goodman, NW, 1995) |
| "The efficacy and safety of prophylactic intravenous ondansetron on prevention of postoperative nausea and vomiting were investigated in 65 ASA grades I-III patients undergoing elective abdominal surgery and receiving general anesthesia." | 7.69 | [Ondansetron on postoperative nausea and vomiting]. ( Guo, XY; Luo, AL; Ye, TH, 1994) |
| "The incidences of nausea and vomiting were significantly lower in the patients premedicated with ondansetron." | 7.69 | [Ondansetron in the prevention of postoperative nausea and vomiting in ambulatory surgery]. ( Bejarano-López, C; Bustos-Molina, F; Cid-Calzada, J; Cortés-Uribe, A; García-Cruz, JJ; Soro-Domingo, M, 1996) |
| "The meclizine group had lower VNRS scores in the PACU at 15 (P = ." | 6.73 | Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population. ( Benfield, DA; Forrester, CM; Kelly, JA; Matern, CE; Pellegrini, JE, 2007) |
| "Emesis is common in the postoperative period following epidural opioid and general anaesthesia." | 6.69 | A double blind comparison of droperidol and ondansetron for prevention of emesis in children undergoing orthopaedic surgery. ( Goodarzi, M, 1998) |
| "Metoclopramide was ineffective." | 6.68 | The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995) |
| " In addition, ondansetron had a similar dose-response curve in both menstruating and nonmenstruating women." | 6.68 | The effects of the menstrual cycle on the incidence of emesis and efficacy of ondansetron. ( Afshar, M; Allen, E; Buxbaum, J; Gratz, I; Joslyn, AF; Prilliman, B, 1996) |
| "Ondansetron was significantly more effective than droperidol in reducing emesis after discharge (P < 0." | 6.68 | Ondansetron decreases postoperative vomiting in pediatric patients undergoing tonsillectomy and adenoidectomy. ( Bower, C; Brown, RE; Kymer, PJ; Lawhorn, CD; Schmitz, ML; Shirey, R; Stoner, J; Vollers, JM, 1996) |
| "Ondansetron is a serotonin (5HT) receptor antagonist at both peripheral and central 5-HT3 receptor sites with no known action on dopamine-mediated activity." | 6.68 | Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. ( Hamilton, DL; McKenzie, R; Riley, TJ; Uy, NT, 1996) |
| "Ondansetron is a well tolerated, efficacious antiemetic which has a similar side effect profile to placebo." | 6.67 | Single dose intravenous ondansetron for the 24-hour treatment of postoperative nausea and vomiting. ( Claybon, L, 1994) |
| "Ondansetron was an effective antiemetic in 78% (14/18) and placebo was effective in 28% (5/18) of the patients." | 6.67 | Treatment of postoperative nausea and vomiting with ondansetron: a randomized, double-blind comparison with placebo. ( Afshar, M; Gratz, I; Larijani, GE; Minassian, S, 1991) |
| "Ondansetron is a serotonin receptor antagonist that is effective in preventing and treating PONV." | 6.39 | Ondansetron: perioperative use of a serotonin receptor antagonist for the prevention and treatment of nausea and vomiting. ( Charbonneau, J; Early, TE; Jenkins, P; McKnight, G, 1995) |
| "Postoperative nausea and vomiting (PONV) is still a common perioperative complication and ondansetron has proved to be an effective antiemetic substance in its prevention." | 6.18 | [Prevention of postoperative nausea and vomiting with single and repeat administration of ondansetron--review of the literature on different administration forms]. ( Buhre, W; Kazmaier, S; Mühr, C; Neumann, P; Saur, P, 1996) |
| "A total of 1442 patients who had major gynaecological surgery were recruited into three multicentre studies using a standard general anaesthetic technique in order to assess the efficacy of various doses of orally administered ondansetron in the prevention of postoperative nausea and vomiting." | 6.17 | Nausea and vomiting after gynaecological surgery: a meta-analysis of factors affecting their incidence. ( Dupeyron, JP; Durham, JM; Haigh, CG; Harmer, M; Kaplan, LA; Kenny, GN, 1993) |
| "Ondansetron is a 5-HT3 receptor antagonist which is effective and well tolerated as an antiemetic for emesis induced by cancer chemotherapy and radiation therapy, and in the prevention and treatment of postoperative nausea and vomiting." | 6.17 | Clinical pharmacology of ondansetron in postoperative nausea and vomiting. ( Baber, N; Frazer, NM; Palmer, JL; Pritchard, JF, 1992) |
| "5 mg IV with ondansetron 8 mg IV for the treatment of nausea and vomiting." | 5.69 | Droperidol versus ondansetron for nausea treatment within the emergency department. ( Clemensen, E; Lau, GT; Philpott, L, 2023) |
| "Promethazine was significantly more effective than ondansetron for treating PONV after failed ondansetron prophylaxis." | 5.34 | A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis. ( Gan, TJ; Habib, AS; Reuveni, J; Taguchi, A; White, WD, 2007) |
| "Palonosetron is a new, potent and long-acting 5HT3-receptorsantagonist that had been approved by the FDA for use in postoperative nausea and vomiting (PONV) prophylaxis." | 5.30 | Efficacy of Palonosetron as Antiemetic Prophylaxis for Post Operative Patients. ( Ahamed, S; Begum, M; Begum, R; Chowdhury, MG; Hossain, M; Hossain, MM; Shuvo, FR, 2019) |
| "To investigate the controlling efficacy of ondasetron and haloperidol in regard to the postcardiotomy delirium." | 5.16 | Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study. ( Daskalopoulos, ME; Gogaki, E; Papaliagkas, V; Parisis, C; Sataitidis, I; Tagarakis, GI; Tsagalas, I; Tsilimingas, NB; Tsolaki, F; Tsolaki, M; Voucharas, C, 2012) |
| " reduces the severity of pruritus and the use of rescue anti-pruritic medication, and improves satisfaction but does not reduce the overall incidence of pruritus in women who have received subarachnoid morphine 150 microg compared to ondansetron 8 mg i." | 5.14 | Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron. ( Carey, M; Choroszczak, P; Immani, S; Ojo, R; Tan, T, 2010) |
| "Of the 380 patients evaluated, significantly fewer ondansetron 4 mg treated patients (89/189; 47%) experienced postoperative nausea and/or vomiting compared with metoclopramide treated patients (115/ 191; 60%) during the study period (p = 0." | 5.13 | Ondansetron vs. metoclopramide for the prevention of nausea and vomiting after gynecologic surgery. ( Diregpoke, S; Krobbuaban, B; Pitakpol, S, 2008) |
| " We evaluated the effects of oral ondansetron disintegrating tablets (ODT) on the incidence of at-home emesis in children undergoing tonsillectomy with and without adenoidectomy and with and without bilateral myringotomy and tube insertion." | 5.13 | The effects of oral ondansetron disintegrating tablets for prevention of at-home emesis in pediatric patients after ear-nose-throat surgery. ( Boretsky, KR; Davis, PJ; Fedel, GM; Fertal, KM; Gurnaney, H; Hoffmann, PC; Ingram, MD; Woelfel, SK; Young, MC, 2008) |
| "We compared the efficacy of inhaled isopropyl alcohol (IPA) with ondansetron for the control of postoperative nausea and vomiting (PONV) during a 24-hour period in 100 ASA class I-III women undergoing laparoscopic surgery." | 5.12 | A comparative analysis of isopropyl alcohol and ondansetron in the treatment of postoperative nausea and vomiting from the hospital setting to the home. ( Cotton, JW; Hood, RR; Pellegrini, JE; Rowell, LR, 2007) |
| "The purpose of this study was to evaluate, in the pediatric ambulatory surgical population, the efficacy of: (i) oral transmucosal fentanyl citrate (OTFC), when given preoperatively, to reduce postoperative excitement associated with sevoflurane, and (ii) intravenous ondansetron to reduce postoperative nausea and vomiting (PONV) associated with OTFC." | 5.11 | The effect of premedication with OTFC, with or without ondansetron, on postoperative agitation, and nausea and vomiting in pediatric ambulatory patients. ( Bachman, C; Binstock, W; Kahana, M; Lynch, JP; McDade, W; Rubin, R, 2004) |
| "In this study, the efficacy and safety of intravenous administration of droperidol followed by oral use of dimenhydrinate did not differ from that of intravenous followed by oral use of ondansetron in children undergoing strabismus surgery." | 5.10 | Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery. ( Bussières, JF; Caron, E; Jacob, JL; Lebel, D; Lortie, L; Mathews, S; Milot, J; Moride, Y, 2003) |
| "In this prospective, randomized, double-blinded study, we compared the prophylactic efficacy of nalbuphine and ondansetron for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 5.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "To assess the efficacy and safety of intravenous ondansetron (4 mg) for the prevention of nausea and vomiting after middle ear surgery under local anesthesia." | 5.09 | Efficacy of ondansetron for prevention of postoperative nausea and vomiting after outpatient ear surgery under local anesthesia. ( Ku, PK; Lo, P; Tong, MC; van Hasselt, CA, 2000) |
| "This prospective, randomized, placebo-controlled, double-blind study was designed to evaluate the efficacy of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting (PONV) after elective craniotomy in adult patients." | 5.09 | Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy. ( Bhatia, A; Dash, HH; Kathirvel, S; Prakash, A; Shenoy, S; Subramaniam, B, 2001) |
| "A prospective double-blind study was conducted to compare the anti-emetic efficacy of ondansetron and droperidol in preventing postoperative emesis following strabismus surgery." | 5.08 | A double-blind randomized prospective study comparing ondansetron with droperidol in the prevention of emesis following strabismus surgery. ( Davis, A; Krige, S; Moyes, D, 1995) |
| " In a double-blind manner, the effects of ondansetron, droperidol, and placebo on the incidence of emesis, postanesthesia care unit stay, and hospital discharge time were evaluated in children undergoing dental surgery." | 5.08 | Effect of antiemetic therapy on recovery and hospital discharge time. A double-blind assessment of ondansetron, droperidol, and placebo in pediatric patients undergoing ambulatory surgery. ( Davis, PJ; Hoffmann, P; Landsman, I; Maloney, K; McGowan, FX, 1995) |
| "Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV)." | 5.08 | Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery. ( Altrock, K; Diefenbach, C; Grond, S; Lehmann, KA; Lynch, J, 1995) |
| "To compare the effectiveness of ondansetron with droperidol in preventing postoperative emesis in children after strabismus repair." | 5.08 | Prevention of emesis after strabismus repair in children: a prospective, double-blinded, randomized comparison of droperidol versus ondansetron. ( Griswold, JD; Lee, A; Litman, RS; Marshall, C; Voisine, R; Wu, CL, 1995) |
| "This randomized, double-blind, multicentre, parallel-group study compared the efficacy and safety of an intravenous dose of ondansetron 4 mg for the prevention of postoperative nausea and vomiting (PONV) with metoclopramide 10 mg and placebo in patients undergoing major gynaecological surgery." | 5.08 | [Intravenous administration of ondansetron vs. metoclopramide for the prophylaxis of postoperative nausea and vomiting]. ( Rust, M, 1995) |
| "We have compared the efficacy of ondansetron, metoclopramide, droperidol and placebo in the prevention of postoperative nausea and vomiting in 118 day stay patients undergoing laparoscopic gynaecological procedures." | 5.08 | Prevention of nausea and vomiting after day case gynaecological laparoscopy. A comparison of ondansetron, droperidol, metoclopramide and placebo. ( McKay, AC; Mirakhur, RK; Paxton, LD, 1995) |
| " Effective prophylaxis for postoperative nausea and vomiting can be achieved in adults with lower doses of ondansetron, a 5-hydroxytryptamine subtype 3 receptor antagonist, compared with chemotherapy-induced emesis." | 5.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "In a randomised, placebo-controlled trial we have compared the efficacy of ondansetron and droperidol in reducing postoperative nausea and vomiting associated with patient-controlled analgesia after orthopaedic surgery." | 5.08 | Comparison of ondansetron and droperidol in reducing postoperative nausea and vomiting associated with patient-controlled analgesia. ( Alexander, R; Jones, RM; Lovell, AT; Seingry, D, 1995) |
| "The aim of this study was to compare the efficacy and safety of ondansetron plus droperidol with each drug alone or placebo in the prevention of postoperative nausea and vomiting (PONV)." | 5.08 | Combination of ondansetron and droperidol in the prophylaxis of postoperative nausea and vomiting. ( Carrascosa, F; García-Pedrajas, F; Iribarren, MJ; Lopez, L; Pueyo, FJ; Saez, A, 1996) |
| " Patients received one of four regimens for the prevention of postoperative nausea and vomiting (PONV): ondansetron 4 mg (n = 25), dexamethasone 8 mg (n = 25), ondansetron with dexamethasone (4 mg and 8 mg, respectively, n = 25) or placebo (saline, n = 25) There were no differences in background factors or factors related to operation and anaesthesia, morphine consumption, pain or side effects between groups." | 5.08 | Combination of ondansetron and dexamethasone in the prophylaxis of postoperative nausea and vomiting. ( Busto, N; Carrascosa, F; López-Olaondo, L; Monedero, P; Pueyo, FJ; Sáez, A, 1996) |
| "Both intravenous ondansetron (OND) and droperidol (DROP) have been observed to reduce vomiting after tonsillectomy in children." | 5.08 | Ondansetron is a better prophylactic antiemetic than droperidol for tonsillectomy in children. ( Baxter, MR; Gould, HM; Hall, LE; MacNeill, HB; Rhine, EJ; Roberts, DW; Splinter, WM, 1995) |
| " This randomized, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of ondansetron in the control of established postoperative emesis in outpatients aged 2-12 yr." | 5.08 | Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group. ( Creed, M; Ginsberg, B; Grunwald, Z; Kaye, R; Khalil, S; Lawhorn, CD; Otto, A; Prillaman, BA; Rodarte, A; Weinstein, M; Weldon, BC; Wheeler, M, 1996) |
| "The efficacy of ondansetron 4 mg and 8 mg was compared with placebo in the reduction of postoperative nausea, retching and vomiting (PONV) after middle ear surgery during general anaesthesia, in 75 patients, in a double-blind and randomized study." | 5.08 | Effect of ondansetron on nausea and vomiting after middle ear surgery during general anaesthesia. ( Honkavaara, P, 1996) |
| "This study has compared the incidences of nausea, vomiting and headache after ondansetron 0." | 5.08 | Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. ( van den Berg, AA, 1996) |
| "The new antiemetic ondansetron is effective for the prophylaxis and treatment of postoperative nausea and vomiting (PONV), but has been subject to limited comparative evaluation in surgical inpatients." | 5.08 | Single-dose prophylaxis for postoperative nausea and vomiting after major abdominal surgery: ondansetron versus droperidol. ( Evans, SF; Paech, MJ; Pavy, TJ, 1995) |
| "The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery." | 5.08 | Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996) |
| "The efficacy of ondansetron and droperidol were evaluated for prophylactic treatment of nausea and vomiting in cesarean section patients under epidural anesthesia." | 5.08 | Intraoperative antiemetic efficacy of prophylactic ondansetron versus droperidol for cesarean section patients under epidural anesthesia. ( Moore, CH; Pan, PH, 1996) |
| "This study determined the overall incidence of postoperative nausea and vomiting (PONV) in 38 patients undergoing laparoscopic gynaecological procedures who received a standardized propofol/isoflurane anaesthetic but no preoperative antiemetic." | 5.08 | A randomized double-blinded comparison of metoclopramide, ondansetron and cyclizine in day-case laparoscopy. ( Watts, SA, 1996) |
| "To compare the antimetic efficacy of prophylactic ondansetron, metoclopramide, and placebo for prevention of postoperative vomiting in pediatric tonsillectomy or adenotonsillectomy patients." | 5.08 | Prospective, randomized, double-blind, placebo-controlled comparison of metoclopramide and ondansetron for prevention of posttonsillectomy or adenotonsillectomy emesis. ( Bohnsack, LE; Bostrom, BC; Seay, RE; Stene, FN; Young, LA, 1996) |
| "Propofol administered to induce and maintain anesthesia is more effective than ondansetron (with thiopental-isoflurane anesthesia) in preventing postoperative vomiting and is associated with fewer requests for rescue antiemetic and sedation in the early phase of recovery." | 5.08 | Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting. ( Gan, TJ; Ginsberg, B; Glass, PS; Grant, AP, 1996) |
| "To determine (1) the efficacy and safety of ondansetron in the prevention of postoperative nausea and vomiting (PONV) in male outpatients; (2) prognostic factors for PONV in male outpatients; and (3) patients' perceptions of the debilitating effects of PONV in the ambulatory surgery setting." | 5.08 | Ondansetron prevents postoperative emesis in male outpatients. S3A-379 Study Group. ( Cox, F; Joslyn, AF; Khalil, SN; Kovac, AL; Pearman, MH; Prillaman, BA; Scuderi, PE, 1996) |
| "Efficiency of ondansetron, a selective 5-HT3 receptor antagonist, in prevention of postoperative nausea and vomiting in 40 ASA I-II patients who will undergo emergency intraabdominal operations is studied in a randomized double-blind and placebo controlled study." | 5.08 | Prophylactic administration of ondansetron in emergency intraabdominal operations. ( Aktürk, G; Albayrak, D; Kalaç, N; Lüleci, N; Ulusoy, HO, 1996) |
| "A randomized, double-blind, placebo-controlled study was designed to compare the relative efficacy of prophylactic ondansetron, 4 mg intravenously (IV), when administered before induction of anesthesia or at the end of surgery to an outpatient population at high risk of developing postoperative nausea and vomiting (PONV)." | 5.08 | The effect of timing of ondansetron administration in outpatients undergoing otolaryngologic surgery. ( Klein, KW; Sun, R; White, PF, 1997) |
| "In a prospective, randomised, double-blind trial, we assessed the relative efficacy of prophylactic ondansetron and metoclopramide administration in the reduction of postoperative nausea and vomiting in 60 patients undergoing routine major neurosurgical procedures." | 5.08 | A comparison of prophylactic ondansetron and metoclopramide administration in patients undergoing major neurosurgical procedures. ( Barsoum, LZ; Jones, NC; Pugh, SC, 1996) |
| "The hypothesis that the addition of dexamethasone to the propofolondansetron combination would significantly reduce postoperative nausea and vomiting (PONV) was not confirmed." | 5.08 | Effect of propofol for induction and ondansetron with or without dexamethasone for the prevention of nausea and vomiting after major gynecologic surgery. ( Hamilton, DL; McKenzie, R; Riley, TJ; Tantisira, B, 1997) |
| "Efficiency of ondansetron, a selective 5- HT3 receptor antagonist, in prevention of postoperative nausea and vomiting in 40 ASA I-II patients to undergo emergency intraabdominal operations is studied in a randomized, double-blind and placebo controlled study." | 5.08 | Prophylactic administration of ondansetron in emergency intraabdominal operations. ( Aktürk, G; Albayrak, D; Kalaç, N; Lüleci, N; Ulusoy, HO, 1997) |
| "To assess the efficacy of 4 mg of intravenous ondansetron versus placebo for the prevention of postoperative nausea and vomiting (PONV) in cholecystectomy, a type of surgery that is highly emetic." | 5.08 | [Efficacy of ondansetron in the prevention of nausea and vomiting after laparoscopic cholecystectomy]. ( Cabrera, JC; Castaño, J; Castillo, J; Escolano, F; Matute, E; Santiveri, X, 1997) |
| "A double-blind, randomised, placebo-controlled trial was conducted to compare the efficacy of metoclopramide with the 5-HT3 antagonist, ondansetron, for the prevention of postoperative emesis in children undergoing elective strabismus surgery." | 5.08 | Efficacy of ondansetron and metoclopramide for preventing postoperative emesis following strabismus surgery in children. ( Mandal, NG; Shende, D, 1997) |
| "To compare the efficacy of oral ondansetron with oral metoclopramide for the prevention of postoperative vomiting and nausea in children undergoing strabismus surgery." | 5.08 | [Does oral ondansetron reduce the incidence of nausea and vomiting after surgery for strabismus in children?]. ( Amraoui, A; Benaguida, M; el Harrar, N; Idali, B; Laouissi, F; Mjahed, K, 1996) |
| "This randomized, double-blind study assessed the impact of two different doses of intraoperative ondansetron on vomiting following tonsillectomy in 240 preadolescent children in a day care surgical setting." | 5.08 | Prophylactic antiemetics in children undergoing tonsillectomy: high-dose vs low-dose ondansetron. ( Rhine, EJ; Splinter, WM, 1997) |
| "To compare the efficacy in the treatment of post-operative nausea and/or vomiting (PONV), 75 patients undergoing gynaecological procedures under general anaesthesia using N2O/enflurane who suffered from PONV in the first hour after surgery were randomly allocated to three groups containing 25 patients each to receive either alizapride 100 mg, droperidol 1 mg or ondansetron 8 mg (i." | 5.08 | Double-blind comparison of alizapride, droperidol and ondansetron in the treatment of post-operative nausea. ( Bovill, JG; de Bont, LE; el-Mofty, M; Samhan, YM; Stienstra, R, 1997) |
| "In a randomised, double-blind study, we have compared the incidence of postoperative nausea and vomitting in 124 patients undergoing major lower limb orthopaedic surgery following oral premedication with temazapam and ondansetron 8 mg, metoclopramide 10 mg or placebo." | 5.08 | Comparison of ondansetron, metoclopramide and placebo as premedicants to reduce nausea and vomiting after major surgery. ( Alexander, R; Fennelly, M, 1997) |
| " This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model." | 5.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| "In this study the antiemetic effects of droperidol, ondansetron and their combination were evaluated in 160 ASA Grade I and II children undergoing surgery for strabismus, who were randomly assigned to one of four groups: Group D received droperidol 75 micrograms kg-1, group O ondansetron 0." | 5.08 | Ondansetron, droperidol and their combination for the prevention of post-operative vomiting in children. ( Braun, U; Klockgether-Radke, A; Mühlendyck, H; Neumann, P; Neumann, S, 1997) |
| "Intravenous dolasetron mesilate has shown efficacy in the prevention of postoperative nausea and vomiting (PONV) when administered as a single dose prior to emergence from anesthesia." | 5.08 | Intravenous dolasetron and ondansetron in prevention of postoperative nausea and vomiting: a multicenter, double-blind, placebo-controlled study. ( Brown, R; Clergue, F; Feiss, P; Hahne, W; Korttila, K; Leeser, J; Nave, S; Olthoff, D; Payeur-Michel, C; Wessel, P, 1997) |
| "To compare the prophylactic administration of ondansetron with droperidol or placebo to determine its effectiveness in reducing postoperative nausea and vomiting after middle ear procedures." | 5.08 | Ondansetron versus droperidol or placebo when given prophylactically for the prevention of postoperative nausea and vomiting in patients undergoing middle ear procedures. ( Fluter, E; Jellish, WS; Leonetti, JP; Thalji, Z, 1997) |
| " The purpose of this study was to compare the efficacy of ondansetron, a highly selective 5-hydroxytryptamine subtype-3 receptor antagonist, with that of metoclopramide for the prevention of postoperative emesis in patients undergoing cataract surgery." | 5.08 | Prophylactic intravenous ondansetron in patients undergoing cataract extraction under general anesthesia. ( Ascaso, FJ; Ayala, I; Carbonell, P; Castro, FJ; Palomar, A, 1997) |
| "1 mg/kg to 4 mg intravenously) compared with placebo in the prevention of postoperative vomiting in 429 ASA status I-III children 1-12 yr old undergoing outpatient surgery under nitrous oxide- and halothane-based general anesthesia." | 5.08 | Single-dose ondansetron prevents postoperative vomiting in pediatric outpatients. ( Cohen, IT; Colingo, K; Creed, MR; Davis, PJ; Donlon, JV; Ferrari, LR; Haberkern, CM; Hannallah, RS; McGowan, FX; Orr, RJ; Parasuraman, TV; Patel, RI; Prillaman, BA; Rimar, S, 1997) |
| "To investigate the incidence of postoperative nausea and vomiting (PONV) depending on the administration time of ondansetron." | 5.08 | [Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients]. ( Kainzwaldner, A; Ploner, F, 1997) |
| "To compare the efficacy of ondansetron, droperidol, or metoclopramide with placebo in preventing postoperative vomiting following strabismus surgery." | 5.08 | A randomized, double-blind, placebo controlled comparison of droperidol, ondansetron, and metoclopramide for the prevention of vomiting following outpatient strabismus surgery in children. ( Elliott, WG; James, RL; Mims, G; Scuderi, PE; Weaver, RG; Weeks, DB, 1997) |
| " After experiencing at least one nausea and/or one emetic episode in the 6 h after recovery from anaesthesia, patients received either ondansetron 4 mg i." | 5.08 | Ondansetron compared with metoclopramide in the treatment of established postoperative nausea and vomiting. The French Ondansetron Study Group. ( Clyti, N; Conseiller, C; Diemunsch, P; Mamet, JP, 1997) |
| "The proportion of patients with nausea was 48%, 50% and 67% in the ondansetron, droperidol and placebo groups, respectively; with a significant difference when both ondansetron (P=0." | 5.08 | Comparison of ondansetron and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women. A randomised, double-blind, placebo-controlled trial. ( Alahuhta, S; Koivuranta, M; Läärä, E; Ranta, P; Ravaska, P, 1997) |
| "To establish a dose-response relationship for ondansetron, and to evaluate any effects of oral premedication with metoclopramide in pediatric patients undergoing tonsillectomy and adenoidectomy and strabismus surgery." | 5.08 | Ondansetron dose response curve in high-risk pediatric patients. ( Kymer, PJ; Lawhorn, CD; Shirey, R; Stewart, FC; Stoner, JM; Volpe, P, 1997) |
| "Low-dose ondansetron plus dexamethasone is an effective prophylactic antiemetic combination for children undergoing strabismus surgery." | 5.08 | Low-dose ondansetron with dexamethasone more effectively decreases vomiting after strabismus surgery in children than does high-dose ondansetron. ( Rhine, EJ; Splinter, WM, 1998) |
| "Ondansetron 4 mg was compared with metoclopramide 10 mg for prevention of post-operative nausea and emesis in in-patients undergoing major gynaecological surgery in this double-blind, randomized, placebo-controlled, multicentre study." | 5.08 | International, multicentre, placebo-controlled study to evaluate the effectiveness of ondansetron vs. metoclopramide in the prevention of post-operative nausea and vomiting. ( Aune, H; Cohen, LA; Feiss, P; Hanson, A; Hasselstrøm, L; Maltby, JR; Morris, RW; Rocke, DA; Rozenberg, B; Rust, M, 1998) |
| " bolus dose of ondansetron 4 mg were evaluated in the prevention of postoperative nausea and vomiting (PONV), which remains one of the most unpleasant side effects experienced by patients postoperatively." | 5.08 | Single i.v. bolus dose of ondansetron in the prevention of postoperative nausea and emesis. ( De Guchteneere, E; Hendrickx, P; Levarlet, M; Moens, P, 1997) |
| "To investigate the hypothesis that the combination of ondansetron and droperidol would be more effective than droperidol alone in reducing nausea and vomiting." | 5.08 | Droperidol-ondansetron combination versus droperidol alone for postoperative control of emesis after total abdominal hysterectomy. ( Hamilton, DL; McKenzie, R; Riley, TJ; Trantisira, BR, 1998) |
| "Children (3-16 yr) undergoing elective strabismus surgery as inpatients were randomly allocated to four anaesthetic techniques: (A) thiopentone induction and isoflurane maintenance; (B) as (A) plus ondansetron 5 mg x m(-2) i." | 5.08 | Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques. ( Fuchs-Buder, T; Rifat, K; Sansonetti, A; Tramèr, MR, 1998) |
| "05 mg kg(-1) +droperidol 20 microg kg(-1) was given as prophylaxis for postoperative pain and emesis, respectively." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
| "More than 2000 patients at high risk of postoperative nausea and vomiting were given either placebo, ondansetron 4 mg, or droperidol 0." | 5.08 | A comparison of the efficacy, safety, and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures. S3A-409 and S3A-410 Study Groups. ( Creed, MR; Duncan, B; Fortney, JT; Gan, TJ; Glass, PS; Graczyk, S; Khalil, S; McKenzie, R; Melson, T; Moote, C; Parasuraman, TV; Parrillo, S; Wermeling, D; Wetchler, B, 1998) |
| "We have compared the effects of ondansetron and perphenazine on vomiting after tonsillectomy in 216 healthy children, aged 2-12 yr." | 5.08 | Prophylaxis for vomiting by children after tonsillectomy: ondansetron compared with perphenazine. ( Rhine, EJ; Splinter, WM, 1998) |
| "This study compares the preoperative administration of ondansetron with that of droperidol or saline solution for the prevention of nausea and vomiting in otologic surgery patients." | 5.08 | Ondansetron versus droperidol or placebo to prevent nausea and vomiting after otologic surgery. ( Fluder, E; Jellish, WS; Leonetti, JP; Thalji, Z, 1998) |
| "To determine the dose-response relationship of ondansetron in preventing postoperative nausea and vomiting (PONV) in women undergoing elective surgery." | 5.08 | A randomized, double-blind, dose-response study of ondansetron in the prevention of postoperative nausea and vomiting. ( Chang, Y; Conant, JA; Connors, PM; Dershwitz, M; Rosow, CE, 1998) |
| "To compare the prophylactic administration of ondansetron plus droperidol, droperidol plus metoclopramide, and perphenazine to determine effects on postoperative nausea, vomiting, and sedation after laparoscopic cholecystectomy." | 5.08 | Prophylactic antiemetics for laparoscopic cholecystectomy: a comparison of perphenazine, droperidol plus ondansetron, and droperidol plus metoclopramide. ( Freiberger, D; Gosnell, JL; Steinbrook, RA, 1998) |
| "The efficacy and safety of ondansetron in preventing postoperative nausea and vomiting following minor oral surgery was evaluated in a prospective randomized double-blind study." | 5.07 | Ondansetron for prevention of postoperative nausea and vomiting following minor oral surgery: a double-blind randomized study. ( Campbell, RC; Chow, J; Hui, E; Lueveswanij, S; Rodrigo, MR; Tong, CK, 1994) |
| " Acetaminophen and meperidine were given for postoperative pain." | 5.07 | Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy. ( Furst, SR; Rodarte, A, 1994) |
| "25 mg droperidol in preventing postoperative vomiting." | 5.07 | [Ondansetron as prophylaxis for postoperative nausea and vomiting. A prospective randomized double-blind comparative study with droperidol]. ( Alon, E; Atanassoff, PG; Biro, P; Lenzlinger, PM, 1994) |
| "Ondansetron is more effective than a placebo in treating postoperative nausea and vomiting (PONV), but it has not been proved to be superior to established antiemetics for prophylaxis or therapy." | 5.07 | [Ondansetron versus droperidol. Postoperative treatment against nausea and vomiting. Comparison of action, adverse effects and acceptance by gynecologic inpatients]. ( Heim, C; Listyo, R; Münzer, T, 1994) |
| "The purpose of this double-blind, randomized study was to compare the effectiveness of ondansetron plus saline versus ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting." | 5.07 | Comparison of ondansetron with ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting. ( Abdelhady, H; Karambelkar, DJ; McKenzie, R; Riley, TJ; Tantisira, B, 1994) |
| "This prospective, randomized, placebo-controlled, double-blinded study evaluated the antiemetic efficacy of ondansetron and metoclopramide in 90 ASA physical status I or II children, 2-17 yr of age, undergoing strabismus repair." | 5.07 | Ondansetron reduces the incidence and severity of poststrabismus repair vomiting in children. ( Corddry, DH; Kettrick, RG; Martin, TM; Rose, JB; Zagnoev, M, 1994) |
| "We performed a double-blind, randomized, placebo-controlled trial to investigate the efficacy and safety of ondansetron in preventing vomiting after tonsillectomy with or without adenoidectomy in children." | 5.07 | Ondansetron decreases emesis after tonsillectomy in children. ( Catanzaro, FA; Litman, RS; Wu, CL, 1994) |
| "In two placebo-controlled, double-blind, multicentre studies, the efficacy and safety of single oral doses of ondansetron 4 mg, 8 mg and 16 mg were evaluated for the prevention of postoperative nausea and vomiting in female inpatients." | 5.07 | Single oral dose ondansetron in the prevention of postoperative nausea and emesis. The European and US Study Groups. ( Cohen, LA; Rust, M, 1994) |
| "We have compared the efficacy of ondansetron with droperidol and saline in the prevention of postoperative nausea and vomiting (PONV) in 120 ASA I and II patients undergoing hip and knee replacements and femoral resections." | 5.07 | Double-blind comparison of ondansetron, droperidol and saline in the prevention of postoperative nausea and vomiting. ( Collis, R; Gan, TJ; Hetreed, M, 1994) |
| "The effect of a single intravenous dose of ondansetron in preventing postoperative nausea and emesis (retching and vomiting) (PONV) was investigated in a randomized, double-blind, placebo-controlled, multicentre, international study." | 5.07 | A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. ( Abrahamsson, J; Briggs, L; Forrler, M; Hellstern, K; Helmers, JH; Moodley, J; Soni, J, 1993) |
| " Patients were stratified by gender and received, in a randomized, double-blind manner, 1, 4, or 8 mg ondansetron or placebo in response to nausea and/or vomiting postoperatively." | 5.07 | Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron. ( Apfelbaum, J; Claybon, L; DuPen, S; Leslie, J; Mingus, M; Scuderi, P; Sharifi-Azad, S; Sung, YF; Talke, P; Wetchler, B, 1993) |
| "Data from the 544 women showed that all doses of intravenous ondansetron tested (1, 4, and 8 mg) were significantly more effective (62%, 76%, and 77%, respectively) than placebo (46%) in reducing the incidence of emesis following surgery until 24 h after recovery room entry." | 5.07 | Comparison of ondansetron versus placebo to prevent postoperative nausea and vomiting in women undergoing ambulatory gynecologic surgery. ( Angel, J; Duncalf, D; Gratz, I; Joslyn, A; Kovac, A; McKenzie, R; McLeskey, C; O'Connor, T; Tolpin, E, 1993) |
| "The efficacy and safety of ondansetron in preventing postoperative nausea and vomiting following major gynaecological surgery was evaluated in this multicentre, double-blind study." | 5.07 | The effect of oral ondansetron in the prevention of postoperative nausea and vomiting after major gynaecological surgery performed under general anaesthesia. ( Conseiller, C; Dupeyron, JP; Gribomont, B; Hemmingsen, C; Kaplan, LA; Levarlet, M; Pedersen, FM; Schoeffler, P, 1993) |
| "The effect of three times daily oral ondansetron in preventing postoperative nausea and vomiting was investigated in two randomized, double-blind, placebo-controlled, multi-centre studies." | 5.07 | Oral ondansetron in the prevention of postoperative nausea and vomiting. ( Helmers, JH, 1992) |
| "The efficacy of ondansetron, a selective 5-HT3 receptor antagonist, in preventing postoperative nausea and vomiting in surgical patients was studied." | 5.07 | Ondansetron is effective in decreasing postoperative nausea and vomiting. ( Dershwitz, M; Di Biase, PM; Joslyn, AF; Rosow, CE; Sanderson, PE, 1992) |
| "In a placebo-controlled, double-blind study, we have compared the efficacy of ondansetron 16 mg, 8 mg and 1 mg administered 8-hourly for prevention of postoperative nausea and vomiting." | 5.07 | Efficacy of orally administered ondansetron in the prevention of postoperative nausea and vomiting: a dose ranging study. ( Haigh, CG; Kenny, GN; Leeser, J; Lip, H; Oates, JD; Onsrud, M; Rowbotham, DJ; Rust, M; Saur, P, 1992) |
| "The efficacy and safety of prophylactic intravenous ondansetron in preventing postoperative nausea and vomiting was investigated in a randomized, stratified, double-blind, placebo-controlled, dose-comparison study of 580 ASA physical class I and II female outpatients undergoing gynaecological surgery and receiving general anaesthesia." | 5.07 | Prophylactic intravenous ondansetron in female outpatients undergoing gynaecological surgery: a multicentre dose-comparison study. ( Angel, J; Duncalf, D; Fagraeus, I; Gratz, I; Joslyn, AF; Kovac, A; McKenzie, R; McLeskey, C; O'Connor, T, 1992) |
| "The safety and efficacy of ondansetron were evaluated in the treatment of postoperative nausea and vomiting." | 5.07 | Ondansetron in the treatment of postoperative nausea and vomiting in ambulatory outpatients: a dose-comparative, stratified, multicentre study. ( Apfelbaum, J; Clayborn, L; Du Pen, S; Leslie, J; Mingus, M; Scuderi, P; Sharifi-Azad, S; Sung, YF; Talke, P; Wetchler, B, 1992) |
| "The effect of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting was investigated in a randomized, double-blind, placebo-controlled study of 84 patients undergoing gynecologic operation and receiving the same general anesthetic." | 5.07 | Prevention of postoperative nausea and vomiting using ondansetron, a new, selective, 5-HT3 receptor antagonist. ( Leeser, J; Lip, H, 1991) |
| "The safety and efficacy of ondansetron were evaluated for the treatment of postoperative nausea and vomiting after laparoscopic surgical procedures." | 5.07 | Antiemetic efficacy of ondansetron after outpatient laparoscopy. ( Bodner, M; White, PF, 1991) |
| "Ondansetron has a preventive effect on PAS without a paralleled side effect of bradycardia." | 4.90 | Efficacy and safety of ondansetron in preventing postanesthesia shivering: a meta-analysis of randomized controlled trials. ( He, K; Liang, SR; Mou, JH; Su, GZ; Tie, HT; Yuan, HW, 2014) |
| "To assess the efficacy of ondansetron and the incidence of headache when used as prophylaxis for postoperative vomiting." | 4.80 | Ondansetron in the prophylaxis of postoperative vomiting: a meta-analysis. ( Canosa, LG; Figueredo, ED, 1998) |
| "For the usual doses recommended for postoperative emesis, there was equivalent effectiveness of ondansetron whether administered as prophylaxis or as a treatment of established vomiting." | 4.80 | Prevention or treatment of postoperative vomiting using ondansetron? A mathematical assessment. ( Canosa, LG; Figueredo, E, 1999) |
| "Ondansetron is effective in the control of nausea and vomiting occurring 24-48 hours after highly emetogenic chemotherapy and after radiotherapy." | 4.79 | The clinical use of ondansetron. New South Wales Therapeutic Assessment Group. ( Currow, DC; Noble, PD; Stuart-Harris, RC, 1995) |
| "The clinical development of ondansetron for the prevention and treatment of postoperative nausea and vomiting has been progressing for 5 years, and continues as new directions of research are being addressed." | 4.79 | Ondansetron, clinical development for postoperative nausea and vomiting: current studies and future directions. ( Joslyn, AF, 1994) |
| "Ondansetron is a new selective serotonin-3-receptor antagonist which has proved to be effective in chemotherapy-induced nausea and vomiting." | 4.79 | [Ondansetron--a new anesthesia relevant antiemetic?]. ( Bach, A; Böhrer, H; Martin, E, 1994) |
| "To test the evidence for a dose-response with ondansetron for treatment of postoperative nausea and vomiting and to establish whether differences in efficacy between doses are of clinical relevance." | 4.79 | A quantitative systematic review of ondansetron in treatment of established postoperative nausea and vomiting. ( McQuay, HJ; Moore, RA; Reynolds, DJ; Tramèr, MR, 1997) |
| "The authors reviewed efficacy and safety data for ondansetron for preventing postoperative nausea and vomiting (PONV)." | 4.79 | Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials. ( McQuay, HJ; Moore, RA; Reynolds, DJ; Tramèr, MR, 1997) |
| "Ondansetron is a selective 5-HT3 receptor antagonist which has previously been reported in the Journal to be a promising new agent for use as prophylaxis against nausea and vomiting caused by chemotherapy and radiotherapy." | 4.78 | Ondansetron. An update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting. ( Markham, A; Sorkin, EM, 1993) |
| "An international clinical trial programme has been established to assess the efficacy and safety of ondansetron in the prevention and treatment of postoperative nausea and vomiting." | 4.78 | The clinical development of ondansetron for use in the prevention and treatment of postoperative nausea and vomiting. ( Haigh, CG; Hellstern, K; Inall, FC; Isal, JP; Joslyn, AF; Kanarek, BK; Kaplan, LA; Povey, PM, 1992) |
| "To evaluate the effect of the 5-HT3-receptor antagonist ondansetron in patients with postcardiotomy delirium." | 3.70 | The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium. ( Akpinar, B; Bayindir, O; Can, E; Demiroğlu, C; Güden, M; Sönmez, B, 2000) |
| "To determine how many patients were deprived of treatment by being given placebo as comparator in trials of ondansetron for postoperative nausea and vomiting." | 3.69 | Denial of effective treatment and poor quality of clinical information in placebo controlled trials of ondansetron for postoperative nausea and vomiting: a review of published trials. ( Aspinall, RL; Goodman, NW, 1995) |
| "The efficacy and safety of prophylactic intravenous ondansetron on prevention of postoperative nausea and vomiting were investigated in 65 ASA grades I-III patients undergoing elective abdominal surgery and receiving general anesthesia." | 3.69 | [Ondansetron on postoperative nausea and vomiting]. ( Guo, XY; Luo, AL; Ye, TH, 1994) |
| "The incidences of nausea and vomiting were significantly lower in the patients premedicated with ondansetron." | 3.69 | [Ondansetron in the prevention of postoperative nausea and vomiting in ambulatory surgery]. ( Bejarano-López, C; Bustos-Molina, F; Cid-Calzada, J; Cortés-Uribe, A; García-Cruz, JJ; Soro-Domingo, M, 1996) |
| "Systematic search for published full reports of randomised controlled trials investigating ondansetron's effect on postoperative emesis." | 3.69 | Impact of covert duplicate publication on meta-analysis: a case study. ( McQuay, HJ; Moore, RA; Reynolds, DJ; Tramèr, MR, 1997) |
| "Treatment with ondansetron was associated with decreased odds of postanesthesia shivering symptoms compared to the control group." | 2.82 | Preventative effect of ondansetron on postanesthesia shivering in children undergoing caudal anesthesia: a randomized double-blinded clinical trial. ( Hu, Y; Huang, W; Jin, Z; Lin, H; Wang, J, 2016) |
| "Postoperative nausea was evaluated with a Numerical Rating Scale, 0 to10, and the frequency of vomiting was recorded for 48 hours." | 2.80 | The efficacy of P6 acupressure with sea-band in reducing postoperative nausea and vomiting in patients undergoing craniotomy: a randomized, double-blinded, placebo-controlled study. ( Bergenheim, T; Karlsson, A; Koskinen, LO; Lindgren, L; Nilsson, I; Nilsson, U, 2015) |
| "Cervical hematoma is hardly a predictable complication of thyroid surgery." | 2.75 | Incidence and circumstances of cervical hematoma complicating thyroidectomy and its relationship to postoperative vomiting. ( Amore Bonapasta, S; Bononi, M; De Cesare, A; Meucci, M; Miccini, M; Scarpini, M; Tocchi, A; Vari, A, 2010) |
| "The meclizine group had lower VNRS scores in the PACU at 15 (P = ." | 2.73 | Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population. ( Benfield, DA; Forrester, CM; Kelly, JA; Matern, CE; Pellegrini, JE, 2007) |
| "Emesis is common in the postoperative period following epidural opioid and general anaesthesia." | 2.69 | A double blind comparison of droperidol and ondansetron for prevention of emesis in children undergoing orthopaedic surgery. ( Goodarzi, M, 1998) |
| "Metoclopramide was ineffective." | 2.68 | The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995) |
| " In addition, ondansetron had a similar dose-response curve in both menstruating and nonmenstruating women." | 2.68 | The effects of the menstrual cycle on the incidence of emesis and efficacy of ondansetron. ( Afshar, M; Allen, E; Buxbaum, J; Gratz, I; Joslyn, AF; Prilliman, B, 1996) |
| "Ondansetron was significantly more effective than droperidol in reducing emesis after discharge (P < 0." | 2.68 | Ondansetron decreases postoperative vomiting in pediatric patients undergoing tonsillectomy and adenoidectomy. ( Bower, C; Brown, RE; Kymer, PJ; Lawhorn, CD; Schmitz, ML; Shirey, R; Stoner, J; Vollers, JM, 1996) |
| "Metoclopramide was ineffective." | 2.68 | Prophylactic antiemetic therapy with ondansetron, tropisetron, granisetron and metoclopramide in patients undergoing laparoscopic cholecystectomy: a randomized, double-blind comparison with placebo. ( Attia, M; Channa, AB; el Bakry, AK; el Gammal, K; el Gammal, M; Elhattab, YS; Jaroudi, R; Khoshim, MH; Naguib, M; Saddique, A, 1996) |
| "Headache was frequent in the control (69%), i." | 2.68 | The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison. ( van den Berg, AA, 1996) |
| "Ondansetron is a serotonin (5HT) receptor antagonist at both peripheral and central 5-HT3 receptor sites with no known action on dopamine-mediated activity." | 2.68 | Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. ( Hamilton, DL; McKenzie, R; Riley, TJ; Uy, NT, 1996) |
| "Nausea was measured at three intervals: at admission to the postanesthesia care unit (PACU), 1 h after admission to the PACU, and on Postoperative Day 1." | 2.68 | A comparison of the prophylactic antiemetic effect of ondansetron and droperidol on patients undergoing gynecologic laparoscopy. ( Alberts, MS; Sniadach, MS, 1997) |
| "Ondansetron is a well tolerated, efficacious antiemetic which has a similar side effect profile to placebo." | 2.67 | Single dose intravenous ondansetron for the 24-hour treatment of postoperative nausea and vomiting. ( Claybon, L, 1994) |
| "ondansetron was superior to metoclopramide in preventing nausea and vomiting after general anaesthesia for day-case gynaecological laparoscopic surgery." | 2.67 | Antiemetic efficacy of prophylactic ondansetron in laparoscopic surgery: randomized, double-blind comparison with metoclopramide. ( Norton, AC; Raphael, JH, 1993) |
| "Ondansetron was an effective antiemetic in 78% (14/18) and placebo was effective in 28% (5/18) of the patients." | 2.67 | Treatment of postoperative nausea and vomiting with ondansetron: a randomized, double-blind comparison with placebo. ( Afshar, M; Gratz, I; Larijani, GE; Minassian, S, 1991) |
| "Ondansetron has been proved to be valid in preventing postanaesthesia shivering (PAS) in several studies." | 2.53 | Efficiency and safety of ondansetron in preventing postanaesthesia shivering. ( He, K; Zhao, H; Zhou, HC, 2016) |
| "Ondansetron is a serotonin receptor antagonist that is effective in preventing and treating PONV." | 2.39 | Ondansetron: perioperative use of a serotonin receptor antagonist for the prevention and treatment of nausea and vomiting. ( Charbonneau, J; Early, TE; Jenkins, P; McKnight, G, 1995) |
| "Ondansetron is a highly potent and selective antagonist at 5-HT3 receptors." | 2.38 | Pharmacology of ondansetron. ( Naylor, RJ; Rudd, JA, 1992) |
| "Promethazine was significantly more effective than ondansetron for treating PONV after failed ondansetron prophylaxis." | 1.34 | A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis. ( Gan, TJ; Habib, AS; Reuveni, J; Taguchi, A; White, WD, 2007) |
| "It is the purpose of this article to discuss ondansetron hydrochloride (Zofran Glaxo, Research Triangle Park, NJ) and its mechanisms of action, indications for use, dosage and administration, side effects, and nursing implications." | 1.29 | Practical points in the use of ondansetron. ( Litwack, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 160 (78.82) | 18.2507 |
| 2000's | 19 (9.36) | 29.6817 |
| 2010's | 23 (11.33) | 24.3611 |
| 2020's | 1 (0.49) | 2.80 |
| Authors | Studies |
|---|---|
| Philpott, L | 1 |
| Clemensen, E | 1 |
| Lau, GT | 1 |
| Schoen, NB | 1 |
| Jermakowicz, WJ | 1 |
| Luca, CC | 1 |
| Jagid, JR | 1 |
| Botros, JM | 1 |
| Mahmoud, AMS | 1 |
| Ragab, SG | 1 |
| Ahmed, MAA | 1 |
| Roushdy, HMS | 1 |
| Yassin, HM | 1 |
| Bolus, ML | 1 |
| Goda, AS | 1 |
| Hossain, MM | 1 |
| Begum, M | 1 |
| Hossain, M | 1 |
| Chowdhury, MG | 1 |
| Begum, R | 1 |
| Ahamed, S | 1 |
| Shuvo, FR | 1 |
| Papadopoulos, G | 1 |
| Pouangare, M | 1 |
| Papathanakos, G | 1 |
| Arnaoutoglou, E | 1 |
| Petrou, A | 1 |
| Tzimas, P | 1 |
| Lirk, P | 1 |
| Hollmann, MW | 1 |
| Obal, D | 1 |
| Yang, D | 1 |
| Sessler, DI | 1 |
| Tie, HT | 1 |
| Su, GZ | 1 |
| He, K | 2 |
| Liang, SR | 1 |
| Yuan, HW | 1 |
| Mou, JH | 1 |
| Afaneh, C | 1 |
| Costa, R | 1 |
| Pomp, A | 1 |
| Dakin, G | 1 |
| Nilsson, I | 1 |
| Karlsson, A | 1 |
| Lindgren, L | 1 |
| Bergenheim, T | 1 |
| Koskinen, LO | 1 |
| Nilsson, U | 1 |
| Maehara, T | 1 |
| Matsumoto, K | 1 |
| Horiguchi, K | 1 |
| Kondo, M | 1 |
| Iino, S | 1 |
| Horie, S | 1 |
| Murata, T | 1 |
| Tsubone, H | 1 |
| Shimada, S | 1 |
| Ozaki, H | 1 |
| Hori, M | 1 |
| Merli, GJ | 1 |
| Weitz, HH | 1 |
| Lin, H | 1 |
| Wang, J | 1 |
| Jin, Z | 1 |
| Hu, Y | 1 |
| Huang, W | 1 |
| Zhao, H | 1 |
| Zhou, HC | 1 |
| Pınar, HU | 1 |
| Karaca, Ö | 1 |
| Doğan, R | 1 |
| Akıllıoğlu, İ | 1 |
| Zhou, C | 1 |
| Zhu, Y | 1 |
| Liu, Z | 1 |
| Ruan, L | 1 |
| Krobbuaban, B | 1 |
| Pitakpol, S | 1 |
| Diregpoke, S | 1 |
| Kumar, N | 1 |
| Hu, WT | 1 |
| Tan, T | 1 |
| Ojo, R | 1 |
| Immani, S | 1 |
| Choroszczak, P | 1 |
| Carey, M | 1 |
| Sistla, S | 2 |
| Rajesh, R | 1 |
| Sadasivan, J | 1 |
| Kundra, P | 1 |
| Bononi, M | 1 |
| Amore Bonapasta, S | 1 |
| Vari, A | 1 |
| Scarpini, M | 1 |
| De Cesare, A | 1 |
| Miccini, M | 1 |
| Meucci, M | 1 |
| Tocchi, A | 1 |
| Stowman, AM | 1 |
| Bothun, ED | 1 |
| Belani, KG | 1 |
| Hoşten, T | 1 |
| Solak, M | 1 |
| Elemen, L | 1 |
| Ozgun, M | 1 |
| Toker, K | 1 |
| Asl, ME | 1 |
| Isazadefar, K | 1 |
| Mohammadian, A | 1 |
| Khoshbaten, M | 1 |
| Tagarakis, GI | 1 |
| Voucharas, C | 1 |
| Tsolaki, F | 1 |
| Daskalopoulos, ME | 1 |
| Papaliagkas, V | 1 |
| Parisis, C | 1 |
| Gogaki, E | 1 |
| Tsagalas, I | 1 |
| Sataitidis, I | 1 |
| Tsolaki, M | 1 |
| Tsilimingas, NB | 1 |
| Abdollahi, MH | 1 |
| Forouzannia, SK | 1 |
| Bagherinasab, M | 1 |
| Barzegar, K | 1 |
| Fekri, A | 1 |
| Sarebanhassanabadi, M | 1 |
| Entezari, A | 1 |
| Puttaswamy, RK | 1 |
| Valap, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Intravenous Granisetron on Incidence and Severity of Intrathecal Morphine Induced Pruritus in Elective Cesarean Section[NCT03483870] | Phase 2 | 80 participants (Actual) | Interventional | 2018-06-01 | Completed | ||
| Quality of Recovery Following Administration of Transverse Abdominus Plane (TAP) Catheter as Compared to Intrathecal Morphine After Cesarean Delivery Under Spinal Anesthesia: a Prospective, Randomized Trial[NCT01593280] | 80 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| Inhalation Intervention for Nausea in the Emergency Department[NCT02092441] | 80 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| A Phase III, Randomized, Open-label, Active-controlled, Two-arm, Parallel-design, Interventional Clinical Trial Evaluating the Efficacy and Safety of Ondansetron 8 mg IV/ IM Injection Compared to Metoclopramide 10 mg in the Management of Nausea and Vomiti[NCT05876585] | Phase 3 | 126 participants (Anticipated) | Interventional | 2023-06-30 | Not yet recruiting | ||
| Optimizing Anesthesia Antiemetic Measures Versus Combination With Dexamethasone or Ondansetron in the Prevention of Postoperative Nausea and Vomiting.[NCT00825071] | Phase 4 | 180 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| Comparison Between Ondansetron 8 mg and Lidocain 40 mg in Preventing Pain Due to Propofol Injection[NCT03134612] | Phase 2 | 104 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708] | 233 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Primary outcome is nausea and vomiting measured on a scale from 0 (no nausea) to 10 (worst nausea imaginable) Verbal Numerical Response Scale (VNRS) at 10 minutes post intervention." (NCT02092441)
Timeframe: 10 minutes post intervention
| Intervention | VNRS (Median) |
|---|---|
| Alcohol Prep Pad Group | 3 |
| Normal Saline Prep Pad | 6 |
"Patient satisfaction of smelling prep pad to alleviate nausea on a scale from 1 (completely unsatisfied) to 5 (completely satisfied)" (NCT02092441)
Timeframe: 10 minutes post intervention
| Intervention | 5 point Likert Scale (Median) |
|---|---|
| Alcohol Prep Pad Group | 4 |
| Normal Saline Prep Pad | 2 |
"Scale ranges from 0 (no pain) to 10 (worst pain imaginable)" (NCT02092441)
Timeframe: 10 minutes post intervention
| Intervention | VNRS (Median) |
|---|---|
| Alcohol Prep Pad Group | 6 |
| Normal Saline Prep Pad | 6 |
Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours
| Intervention | hours (Median) |
|---|---|
| Intervention Cohort | 26.4 |
| Comparison Cohort | 28.2 |
To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital
| Intervention | percentage of subjects with PDN (Number) |
|---|---|
| Intervention Cohort | 72 |
| Comparison Cohort | 60 |
(NCT01592708)
Timeframe: 1 week post discharge
| Intervention | percentage of subjects with PDV (Number) |
|---|---|
| Intervention Cohort | 22 |
| Comparison Cohort | 29 |
End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with PON (Number) |
|---|---|
| Intervention Cohort | 24 |
| Comparison Cohort | 70 |
(NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with POV (Number) |
|---|---|
| Intervention Cohort | 11 |
| Comparison Cohort | 28 |
26 reviews available for ondansetron and Postoperative Complications
| Article | Year |
|---|---|
Efficacy and safety of ondansetron in preventing postanesthesia shivering: a meta-analysis of randomized controlled trials.
Topics: Bradycardia; Humans; Ondansetron; Postoperative Complications; Randomized Controlled Trials as Topic | 2014 |
Web Exclusives. The consult guys - twisted after surgery: what caused torsades?
Topics: Antiemetics; Craniotomy; Electrocardiography; Female; Humans; Hypotension; Intracranial Aneurysm; Mi | 2015 |
Efficiency and safety of ondansetron in preventing postanaesthesia shivering.
Topics: Anesthesia Recovery Period; Humans; Hypotension; Ondansetron; Postoperative Complications; Randomize | 2016 |
5-HT3 receptor antagonists for the prevention of postoperative shivering: a meta-analysis.
Topics: Analgesics, Opioid; Granisetron; Humans; Indoles; Isoquinolines; Meperidine; Ondansetron; Palonosetr | 2016 |
The vomiting reflex and the role of 5-HT3 receptors.
Topics: Afferent Pathways; Animals; Antiemetics; Antineoplastic Agents; Brain Stem; Chemoreceptor Cells; Fer | 1993 |
Ondansetron. An update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting.
Topics: Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Humans; Nausea; Ond | 1993 |
Recent advances in the understanding and management of postoperative nausea and vomiting.
Topics: Antiemetics; Child; Female; Humans; Male; Nausea; Ondansetron; Postoperative Complications; Serotoni | 1994 |
The clinical use of ondansetron. New South Wales Therapeutic Assessment Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D | 1995 |
Ondansetron, clinical development for postoperative nausea and vomiting: current studies and future directions.
Topics: Adult; Aged; Analgesics, Opioid; Child; Drug Administration Schedule; Female; Humans; Nausea; Ondans | 1994 |
[Ondansetron--a new anesthesia relevant antiemetic?].
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1994 |
Nausea and vomiting after gynaecological surgery: a meta-analysis of factors affecting their incidence.
Topics: Adolescent; Adult; Age Factors; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; | 1993 |
Ondansetron for postoperative nausea and vomiting.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1993 |
Ondansetron: perioperative use of a serotonin receptor antagonist for the prevention and treatment of nausea and vomiting.
Topics: Antiemetics; Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1995 |
[Prevention and treatment of postoperative nausea and vomiting with 5-HT3-receptor blockers].
Topics: Antiemetics; Clinical Trials as Topic; Dose-Response Relationship, Drug; Granisetron; Humans; Indole | 1996 |
[Prevention of postoperative nausea and vomiting with single and repeat administration of ondansetron--review of the literature on different administration forms].
Topics: Adult; Aged; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration | 1996 |
A quantitative systematic review of ondansetron in treatment of established postoperative nausea and vomiting.
Topics: Antiemetics; Dose-Response Relationship, Drug; Humans; Nausea; Ondansetron; Postoperative Complicati | 1997 |
Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials.
Topics: Antiemetics; Dose-Response Relationship, Drug; Headache; Humans; Liver; Nausea; Ondansetron; Postope | 1997 |
Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials.
Topics: Antiemetics; Dose-Response Relationship, Drug; Headache; Humans; Liver; Nausea; Ondansetron; Postope | 1997 |
Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials.
Topics: Antiemetics; Dose-Response Relationship, Drug; Headache; Humans; Liver; Nausea; Ondansetron; Postope | 1997 |
Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials.
Topics: Antiemetics; Dose-Response Relationship, Drug; Headache; Humans; Liver; Nausea; Ondansetron; Postope | 1997 |
Ondansetron in the prophylaxis of postoperative vomiting: a meta-analysis.
Topics: Administration, Oral; Adult; Antiemetics; Child; Female; Follow-Up Studies; Headache; Humans; Incide | 1998 |
[Serotonin antagonists in the treatment of postoperative nausea and vomiting].
Topics: Adult; Antiemetics; Child; Humans; Nausea; Ondansetron; Postoperative Complications; Serotonin Antag | 1998 |
Prevention or treatment of postoperative vomiting using ondansetron? A mathematical assessment.
Topics: Antiemetics; Evaluation Studies as Topic; Humans; Mathematics; Odds Ratio; Ondansetron; Postoperativ | 1999 |
Clinical pharmacology of ondansetron in postoperative nausea and vomiting.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1992 |
Incidence and aetiology of postoperative nausea and vomiting.
Topics: Humans; Incidence; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1992 |
Pharmacology of ondansetron.
Topics: Animals; Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1992 |
The clinical development of ondansetron for use in the prevention and treatment of postoperative nausea and vomiting.
Topics: Clinical Trials as Topic; Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1992 |
[Prevention of postoperative nausea and vomiting by ondansetron].
Topics: Administration, Oral; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Nause | 1992 |
5-HT3 antagonists in postoperative nausea and vomiting.
Topics: Aged; Anesthesia, General; Humans; Male; Metoclopramide; Nausea; Ondansetron; Postoperative Complica | 1992 |
137 trials available for ondansetron and Postoperative Complications
| Article | Year |
|---|---|
Droperidol versus ondansetron for nausea treatment within the emergency department.
Topics: Adult; Antiemetics; Double-Blind Method; Droperidol; Emergency Service, Hospital; Humans; Nausea; On | 2023 |
Comparative study between Dexmedetomidine and Ondansteron for prevention of post spinal shivering. A randomized controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Humans; | 2018 |
Efficacy of Palonosetron as Antiemetic Prophylaxis for Post Operative Patients.
Topics: Administration, Intravenous; Adult; Anesthesia, General; Antiemetics; Bangladesh; Cholecystectomy, L | 2019 |
The effect of ondansetron on postoperative delirium and cognitive function in aged orthopedic patients.
Topics: Aged; Anesthesia, General; Cognition Disorders; Delirium; Double-Blind Method; Female; Femoral Fract | 2014 |
A prospective randomized controlled trial assessing the efficacy of omentopexy during laparoscopic sleeve gastrectomy in reducing postoperative gastrointestinal symptoms.
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Follow-Up Studies; Gastrectomy; Gastroesophag | 2015 |
The efficacy of P6 acupressure with sea-band in reducing postoperative nausea and vomiting in patients undergoing craniotomy: a randomized, double-blinded, placebo-controlled study.
Topics: Acupressure; Adult; Aged; Anesthesia, General; Antiemetics; Craniotomy; Double-Blind Method; Female; | 2015 |
Preventative effect of ondansetron on postanesthesia shivering in children undergoing caudal anesthesia: a randomized double-blinded clinical trial.
Topics: Adolescent; Anesthesia, Caudal; Anesthetics; Blood Pressure; Body Temperature; Child; Double-Blind M | 2016 |
Ondansetron vs. metoclopramide for the prevention of nausea and vomiting after gynecologic surgery.
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Meto | 2008 |
Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Double-Bli | 2010 |
Does single-dose preoperative dexamethasone minimize stress response and improve recovery after laparoscopic cholecystectomy?
Topics: Adult; Anti-Inflammatory Agents; Antiemetics; C-Reactive Protein; Cholecystectomy, Laparoscopic; Dex | 2009 |
Incidence and circumstances of cervical hematoma complicating thyroidectomy and its relationship to postoperative vomiting.
Topics: Adult; Aged; Chi-Square Distribution; Dexamethasone; Dose-Response Relationship, Drug; Drug Administ | 2010 |
Ondansetron does not modify emergence agitation in children.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, | 2011 |
Ondansetron and meperidine prevent postoperative shivering after general anesthesia.
Topics: Adult; Anesthetics, General; Double-Blind Method; Female; Humans; Meperidine; Ondansetron; Postopera | 2011 |
Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Cardiac Surgical Procedures; Delirium; Double-Blind M | 2012 |
The effect of ondansetron and meperedin on preventing shivering after off-pump coronary artery bypass graft.
Topics: Analgesics, Opioid; Coronary Artery Bypass, Off-Pump; Double-Blind Method; Female; Humans; Male; Mep | 2012 |
Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery.
Topics: Administration, Oral; Antiemetics; Child; Child, Preschool; Dimenhydrinate; Double-Blind Method; Dro | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
The effect of premedication with OTFC, with or without ondansetron, on postoperative agitation, and nausea and vomiting in pediatric ambulatory patients.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthetics, Inhalation; A | 2004 |
A comparative analysis of isopropyl alcohol and ondansetron in the treatment of postoperative nausea and vomiting from the hospital setting to the home.
Topics: 2-Propanol; Adult; Antiemetics; Female; Humans; Laparoscopy; Nausea; Ondansetron; Postoperative Comp | 2007 |
Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population.
Topics: Adult; Drug Therapy, Combination; Elective Surgical Procedures; Female; Humans; Male; Meclizine; Mid | 2007 |
Combination of antiemetics for the prevention of postoperative nausea and vomiting in high-risk patients.
Topics: Adult; Anesthetics; Antiemetics; Dexamethasone; Female; Humans; Incidence; Korea; Middle Aged; Ondan | 2007 |
The effects of oral ondansetron disintegrating tablets for prevention of at-home emesis in pediatric patients after ear-nose-throat surgery.
Topics: Adenoidectomy; Administration, Oral; Antiemetics; Child; Double-Blind Method; Humans; Ondansetron; O | 2008 |
A double-blind randomized prospective study comparing ondansetron with droperidol in the prevention of emesis following strabismus surgery.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Antiemetics; Child; Dopamine Antagonists; Do | 1995 |
Effect of antiemetic therapy on recovery and hospital discharge time. A double-blind assessment of ondansetron, droperidol, and placebo in pediatric patients undergoing ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperido | 1995 |
Rapid intravenous administration of ondansetron or metoclopramide is not associated with cardiovascular compromise in children.
Topics: Adolescent; Age Factors; Antiemetics; Blood Pressure; Body Weight; Child; Child, Preschool; Double-B | 1995 |
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension | 1995 |
Ondansetron for prevention of postoperative nausea and vomiting following minor oral surgery: a double-blind randomized study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Bloo | 1994 |
Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery.
Topics: Adult; Anesthesia; Double-Blind Method; Droperidol; Female; Genitalia, Female; Humans; Isoflurane; M | 1995 |
Prevention of emesis after strabismus repair in children: a prospective, double-blinded, randomized comparison of droperidol versus ondansetron.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Child; Child, Preschool; Dou | 1995 |
[Intravenous administration of ondansetron vs. metoclopramide for the prophylaxis of postoperative nausea and vomiting].
Topics: Adult; Double-Blind Method; Female; Genital Diseases, Female; Humans; Injections, Intravenous; Metoc | 1995 |
Prevention of nausea and vomiting after day case gynaecological laparoscopy. A comparison of ondansetron, droperidol, metoclopramide and placebo.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Double-Blind Method; Droperidol; Female; | 1995 |
The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Child; Child, Preschool; Dose-Response Relation | 1995 |
Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy.
Topics: Acetaminophen; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperidol; Female; Humans | 1994 |
Effects of ondansetron in the prevention of postoperative nausea and vomiting in children.
Topics: Anesthesia, General; Anesthesia, Inhalation; Child; Child, Preschool; Dose-Response Relationship, Dr | 1994 |
[Ondansetron as prophylaxis for postoperative nausea and vomiting. A prospective randomized double-blind comparative study with droperidol].
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Droperidol; Female; Genitalia, Female; Humans; | 1994 |
[Ondansetron versus droperidol. Postoperative treatment against nausea and vomiting. Comparison of action, adverse effects and acceptance by gynecologic inpatients].
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Droperidol; Female; Genitalia, Female; Humans; | 1994 |
Ondansetron prevents postoperative nausea and vomiting in women outpatients.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Nausea; Ondansetron; Outp | 1994 |
Comparison of ondansetron with ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Huma | 1994 |
Ondansetron reduces the incidence and severity of poststrabismus repair vomiting in children.
Topics: Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Ondansetron; Postope | 1994 |
Ondansetron decreases emesis after tonsillectomy in children.
Topics: Child; Child, Preschool; Double-Blind Method; Humans; Ondansetron; Postoperative Complications; Tons | 1994 |
Single dose intravenous ondansetron in the prevention of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Dose-Response Relationship, Drug; Double-Bl | 1994 |
Single oral dose ondansetron in the prevention of postoperative nausea and emesis. The European and US Study Groups.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind | 1994 |
Single dose intravenous ondansetron for the 24-hour treatment of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Human | 1994 |
Double-blind comparison of ondansetron, droperidol and saline in the prevention of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General; Double-Blind | 1994 |
Nausea and vomiting after gynaecological surgery: a meta-analysis of factors affecting their incidence.
Topics: Adolescent; Adult; Age Factors; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; | 1993 |
Antiemetic efficacy of prophylactic ondansetron in laparoscopic surgery: randomized, double-blind comparison with metoclopramide.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, General; Double-Blind Method; Female; | 1993 |
A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Bradycardia; Constipation; Double-Blind Method; Female | 1993 |
Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron.
Topics: Adult; Ambulatory Surgical Procedures; Double-Blind Method; Female; Humans; Male; Nausea; Ondansetro | 1993 |
Comparison of ondansetron versus placebo to prevent postoperative nausea and vomiting in women undergoing ambulatory gynecologic surgery.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Double-Blind Method; Female; Humans; Laparoscopy; Middl | 1993 |
The effect of oral ondansetron in the prevention of postoperative nausea and vomiting after major gynaecological surgery performed under general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Belgium; Double-Blind Method; Drug Administration Sche | 1993 |
Cost-effectiveness analysis of antiemetic therapy for ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Antiemetics; Cost-Benefit Analysis; Droperidol; Humans; Ondansetron; | 1995 |
Postoperative emesis following otoplasty in children.
Topics: Adolescent; Anesthesia, General; Antiemetics; Child; Child, Preschool; Drinking; Droperidol; Ear, Ex | 1995 |
Comparison of ondansetron and droperidol in reducing postoperative nausea and vomiting associated with patient-controlled analgesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Antiemetics; Droperidol; | 1995 |
Recovery profile after desflurane with or without ondansetron compared with propofol in patients undergoing outpatient gynecological laparoscopy.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics; Anesthesia Recovery Period; Anestheti | 1996 |
Preoperative oral ondansetron for pediatric tonsillectomy.
Topics: Administration, Oral; Anesthesia, Inhalation; Anesthetics, Inhalation; Antiemetics; Child; Child, Pr | 1996 |
Combination of ondansetron and droperidol in the prophylaxis of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Droperidol; Drug Therapy, Combination; Fe | 1996 |
Combination of ondansetron and dexamethasone in the prophylaxis of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Antiemetics; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; | 1996 |
A comparison of costs and efficacy of ondansetron and droperidol as prophylactic antiemetic therapy for elective outpatient gynecologic procedures.
Topics: Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Antiemetics; Anxiety; Conscious S | 1996 |
Effects of ondansetron on emesis in the first 24 hours after craniotomy in children.
Topics: Adolescent; Antiemetics; Brain; Cerebellum; Child; Child, Preschool; Craniotomy; Double-Blind Method | 1996 |
Ondansetron is a better prophylactic antiemetic than droperidol for tonsillectomy in children.
Topics: Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperidol; Humans; Ondansetron; Postoper | 1995 |
Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group.
Topics: Antiemetics; Child; Child, Preschool; Double-Blind Method; Female; Humans; Injections, Intravenous; | 1996 |
Effect of ondansetron on nausea and vomiting after middle ear surgery during general anaesthesia.
Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Double-Blind Method; Ear, Middle; Female; Human | 1996 |
The effects of the menstrual cycle on the incidence of emesis and efficacy of ondansetron.
Topics: Adult; Antiemetics; Dose-Response Relationship, Drug; Female; Humans; Menstrual Cycle; Multicenter S | 1996 |
Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy.
Topics: Adenoidectomy; Adolescent; Adult; Aged; Antiemetics; Child; Child, Preschool; Double-Blind Method; F | 1996 |
Single-dose prophylaxis for postoperative nausea and vomiting after major abdominal surgery: ondansetron versus droperidol.
Topics: Abdomen; Antiemetics; Droperidol; Female; Humans; Injections, Intravenous; Intraoperative Period; Mi | 1995 |
The prevention of postoperative nausea and vomiting using a combination of ondansetron and droperidol.
Topics: Adult; Analgesia, Patient-Controlled; Antiemetics; Droperidol; Drug Therapy, Combination; Female; Hu | 1996 |
Ondansetron decreases postoperative vomiting in pediatric patients undergoing tonsillectomy and adenoidectomy.
Topics: Adenoidectomy; Antiemetics; Child; Child, Preschool; Double-Blind Method; Humans; Ondansetron; Posto | 1996 |
Prophylactic antiemetic therapy with ondansetron, tropisetron, granisetron and metoclopramide in patients undergoing laparoscopic cholecystectomy: a randomized, double-blind comparison with placebo.
Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Granisetron; H | 1996 |
Posttonsillectomy vomiting. Ondansetron or metoclopramide during paediatric tonsillectomy: are two doses better than one?
Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anes | 1996 |
A comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after tympanoplasty.
Topics: Adolescent; Adult; Antiemetics; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Nause | 1996 |
Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans; Hysterectom | 1996 |
Intraoperative antiemetic efficacy of prophylactic ondansetron versus droperidol for cesarean section patients under epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Double-Blind Me | 1996 |
Prophylactic antiemetics for laparoscopic cholecystectomy: ondansetron versus droperidol plus metoclopramide.
Topics: Adrenergic Agonists; Adult; Antiemetics; Atropine; Chemoprevention; Cholecystectomy, Laparoscopic; C | 1996 |
[Treatment of postoperative nausea and vomiting with ondansetron in patients administered anti-neoplastic agents].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; | 1996 |
The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison.
Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Blood Pressure; Child; Double-Blind Method; Fem | 1996 |
A randomized double-blinded comparison of metoclopramide, ondansetron and cyclizine in day-case laparoscopy.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, | 1996 |
Prospective, randomized, double-blind, placebo-controlled comparison of metoclopramide and ondansetron for prevention of posttonsillectomy or adenotonsillectomy emesis.
Topics: Adenoidectomy; Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Antiemetics; Child; Chil | 1996 |
Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting.
Topics: Adult; Breast; Double-Blind Method; Female; Humans; Metabolic Clearance Rate; Middle Aged; Nausea; O | 1996 |
[Prevention of postoperative nausea and vomiting with ondansetron: a prospective, randomized, double-blind study in 90 patients].
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Ondansetro | 1995 |
Droperidol/ondansetron combination controls nausea and vomiting after tubal banding.
Topics: Antiemetics; Dopamine Antagonists; Double-Blind Method; Droperidol; Drug Combinations; Female; Human | 1996 |
Ondansetron prevents postoperative emesis in male outpatients. S3A-379 Study Group.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Antiemetics; | 1996 |
Prophylactic administration of ondansetron in emergency intraabdominal operations.
Topics: Abdomen; Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Emergencies; Female; Humans; Mal | 1996 |
[Activity of ondansetron on the systemic vascular resistance and venous capacitance during cardiopulmonary bypass].
Topics: Aged; Antiemetics; Blood Pressure; Blood Volume; Cardiopulmonary Bypass; Catecholamines; Extracorpor | 1996 |
The effect of timing of ondansetron administration in outpatients undergoing otolaryngologic surgery.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Double-Blind Method; Drug Administration S | 1997 |
A comparison of prophylactic ondansetron and metoclopramide administration in patients undergoing major neurosurgical procedures.
Topics: Antiemetics; Double-Blind Method; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neurosu | 1996 |
[Prevention of postoperative nausea and vomiting with single and repeat administration of ondansetron--review of the literature on different administration forms].
Topics: Adult; Aged; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration | 1996 |
Effect of propofol for induction and ondansetron with or without dexamethasone for the prevention of nausea and vomiting after major gynecologic surgery.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Antiemetics; Dexamethaso | 1997 |
Prophylactic administration of ondansetron in emergency intraabdominal operations.
Topics: Abdomen; Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Emergency Medical Services; Fema | 1997 |
Intravenous ondansetron for postsurgical opioid-induced nausea and vomiting. S3A-255 Study Group.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans | 1997 |
[Efficacy of ondansetron in the prevention of nausea and vomiting after laparoscopic cholecystectomy].
Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Humans; Middle | 1997 |
Efficacy of ondansetron and metoclopramide for preventing postoperative emesis following strabismus surgery in children.
Topics: Age Distribution; Antiemetics; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infant; | 1997 |
[Does oral ondansetron reduce the incidence of nausea and vomiting after surgery for strabismus in children?].
Topics: Administration, Oral; Adolescent; Antiemetics; Child; Female; Humans; Male; Metoclopramide; Nausea; | 1996 |
Prophylactic antiemetics in children undergoing tonsillectomy: high-dose vs low-dose ondansetron.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anesthesia, Intravenous; Antiemetics; Child; | 1997 |
Double-blind comparison of alizapride, droperidol and ondansetron in the treatment of post-operative nausea.
Topics: Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Droperidol; Female; Genitalia, Female; Hu | 1997 |
Comparison of ondansetron, metoclopramide and placebo as premedicants to reduce nausea and vomiting after major surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Double-Blind Method; Female; Humans; Male; | 1997 |
Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemet | 1997 |
Ondansetron, droperidol and their combination for the prevention of post-operative vomiting in children.
Topics: Adolescent; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperidol; Drug Therapy, Com | 1997 |
Intravenous dolasetron and ondansetron in prevention of postoperative nausea and vomiting: a multicenter, double-blind, placebo-controlled study.
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Indoles; Injections, Intravenous; Mal | 1997 |
Ondansetron versus droperidol or placebo when given prophylactically for the prevention of postoperative nausea and vomiting in patients undergoing middle ear procedures.
Topics: Adult; Antiemetics; Double-Blind Method; Droperidol; Ear, Middle; Female; Humans; Male; Middle Aged; | 1997 |
Prophylactic intravenous ondansetron in patients undergoing cataract extraction under general anesthesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Antiemetics; Cataract Extraction; C | 1997 |
Single-dose ondansetron prevents postoperative vomiting in pediatric outpatients.
Topics: Anesthesia, General; Anesthetics, Inhalation; Antiemetics; Child; Child, Preschool; Double-Blind Met | 1997 |
[Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients].
Topics: Adult; Anesthesia; Antiemetics; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Onda | 1997 |
Vomiting after strabismus surgery in children: ondansetron vs propofol.
Topics: Adolescent; Antiemetics; Child; Child, Preschool; Female; Health Care Costs; Humans; Male; Ondansetr | 1997 |
A comparison of the prophylactic antiemetic effect of ondansetron and droperidol on patients undergoing gynecologic laparoscopy.
Topics: Adolescent; Adult; Antiemetics; Double-Blind Method; Droperidol; Female; Health Care Costs; Humans; | 1997 |
A randomized, double-blind, placebo controlled comparison of droperidol, ondansetron, and metoclopramide for the prevention of vomiting following outpatient strabismus surgery in children.
Topics: Ambulatory Surgical Procedures; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperido | 1997 |
The anti-emetic efficacy of a combination of ondansetron and droperidol.
Topics: Adult; Aged; Anesthesia, General; Antiemetics; Double-Blind Method; Droperidol; Drug Therapy, Combin | 1997 |
Ondansetron compared with metoclopramide in the treatment of established postoperative nausea and vomiting. The French Ondansetron Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Antiemetics; Double-Blind Method; F | 1997 |
Comparison of ondansetron and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women. A randomised, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Double-Blind Method; Droperidol; Female; Hu | 1997 |
Comparison of ondansetron, metoclopramide, and placebo in the prevention of postoperative emesis in children undergoing ophthalmic surgery.
Topics: Adolescent; Antiemetics; Child; Child, Preschool; Eye Diseases; Humans; Infant; Metoclopramide; Onda | 1997 |
Ondansetron dose response curve in high-risk pediatric patients.
Topics: Adenoidectomy; Antiemetics; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind | 1997 |
Low-dose ondansetron with dexamethasone more effectively decreases vomiting after strabismus surgery in children than does high-dose ondansetron.
Topics: Antiemetics; Child; Child, Preschool; Dexamethasone; Double-Blind Method; Health Care Costs; Humans; | 1998 |
Ondansetron is not superior to moderate dose metoclopramide in the prevention of post-operative nausea and vomiting after minor gynaecological surgery.
Topics: Adult; Antiemetics; Dilatation and Curettage; Double-Blind Method; Female; Gynecologic Surgical Proc | 1997 |
International, multicentre, placebo-controlled study to evaluate the effectiveness of ondansetron vs. metoclopramide in the prevention of post-operative nausea and vomiting.
Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Double-Blind Method; Female; Gynecologic Surgic | 1998 |
Single i.v. bolus dose of ondansetron in the prevention of postoperative nausea and emesis.
Topics: Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Injections, Intravenous; | 1997 |
Droperidol-ondansetron combination versus droperidol alone for postoperative control of emesis after total abdominal hysterectomy.
Topics: Adult; Antiemetics; Double-Blind Method; Droperidol; Drug Combinations; Female; Humans; Hysterectomy | 1998 |
Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques.
Topics: Adolescent; Alfentanil; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Anesthetic | 1998 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
A comparison of the efficacy, safety, and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures. S3A-409 and S3A-410 Study Groups.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics, Inhal | 1998 |
Prophylaxis for vomiting by children after tonsillectomy: ondansetron compared with perphenazine.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anesthesia, Intravenous; Antiemetics; Child; | 1998 |
Ondansetron versus droperidol or placebo to prevent nausea and vomiting after otologic surgery.
Topics: Adult; Antiemetics; Droperidol; Female; Humans; Male; Middle Aged; Nausea; Ondansetron; Otorhinolary | 1998 |
A randomized, double-blind, dose-response study of ondansetron in the prevention of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Dose-Response Relationship, Drug; Double-Bl | 1998 |
A double blind comparison of droperidol and ondansetron for prevention of emesis in children undergoing orthopaedic surgery.
Topics: Adolescent; Anesthesia, Epidural; Anesthesia, General; Antiemetics; Child; Child, Preschool; Double- | 1998 |
Prophylactic antiemetics for laparoscopic cholecystectomy: a comparison of perphenazine, droperidol plus ondansetron, and droperidol plus metoclopramide.
Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Droperidol; Female; Hu | 1998 |
The impact of the menstrual cycle and ondansetron on postoperative nausea and vomiting.
Topics: Adolescent; Adult; Antiemetics; Female; Humans; Menstrual Cycle; Nausea; Ondansetron; Postoperative | 1998 |
Efficacy of ondansetron for prevention of postoperative nausea and vomiting after outpatient ear surgery under local anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Antiemetics; Double-Blind Method; Female; Humans; Inject | 2000 |
Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy.
Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia; Antiemetics; Brain Neoplasms; Craniotomy; Dexamethas | 2001 |
Oral ondansetron in the prevention of postoperative nausea and vomiting.
Topics: Administration, Oral; Adult; Alanine Transaminase; Aspartate Aminotransferases; Constipation; Double | 1992 |
Ondansetron is effective in decreasing postoperative nausea and vomiting.
Topics: Abdomen; Adult; Antiemetics; Double-Blind Method; Female; Humans; Imidazoles; Injections, Intravenou | 1992 |
Efficacy of orally administered ondansetron in the prevention of postoperative nausea and vomiting: a dose ranging study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anesthesia, Obstetrical; Antiemetics; Double-Blind Me | 1992 |
Ondansetron in the treatment of postoperative vomiting: a randomized, double-blind comparison with droperidol and metoclopramide.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Antiemetics; Dilatation and Curettage; Double-B | 1992 |
Clinical pharmacology of ondansetron in postoperative nausea and vomiting.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1992 |
Prophylactic intravenous ondansetron in female outpatients undergoing gynaecological surgery: a multicentre dose-comparison study.
Topics: Adult; Ambulatory Surgical Procedures; Double-Blind Method; Female; Humans; Injections, Intravenous; | 1992 |
Ondansetron in the treatment of postoperative nausea and vomiting in ambulatory outpatients: a dose-comparative, stratified, multicentre study.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Child; Female; Headache; Humans; Injections | 1992 |
[Prevention of postoperative nausea and vomiting by ondansetron].
Topics: Administration, Oral; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Nause | 1992 |
Prevention of postoperative nausea and vomiting using ondansetron, a new, selective, 5-HT3 receptor antagonist.
Topics: Adult; Aged; Anesthesia, General; Antiemetics; Double-Blind Method; Drug Evaluation; Female; Humans; | 1991 |
Treatment of postoperative nausea and vomiting with ondansetron: a randomized, double-blind comparison with placebo.
Topics: Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Imidazoles; Male; Middle | 1991 |
Antiemetic efficacy of ondansetron after outpatient laparoscopy.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Antiemetics; Double-Blind Method; Female; Humans; | 1991 |
44 other studies available for ondansetron and Postoperative Complications
| Article | Year |
|---|---|
Acute symptomatic peri-lead edema 33 hours after deep brain stimulation surgery: a case report.
Topics: Anti-Inflammatory Agents; Brain Edema; Deep Brain Stimulation; Dexamethasone; Headache; Humans; Male | 2017 |
Ondansetron: a new therapeutic option to attenuate postoperative cognitive dysfunction and delirium?
Topics: Cognition Disorders; Delirium; Female; Humans; Male; Ondansetron; Postoperative Complications; Serot | 2014 |
Perioperative doses of ondansetron or dolasetron do not lengthen the QT interval.
Topics: Aged; Aged, 80 and over; Female; Heart Rate; Humans; Indoles; Long QT Syndrome; Male; Middle Aged; O | 2014 |
Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in post-operative ileus.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Gastrointestinal Transit; Ileus; Indoles; Isoquinoline | 2015 |
Can ondansetron be used in the treatment of subdural block?
Topics: Anesthesia, Caudal; Child; Circumcision, Male; Humans; Male; Ondansetron; Postoperative Complication | 2016 |
Extrapyramidal reaction to ondansetron and propofol.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemetics; Basal Ganglia Diseases; Di | 2009 |
Discomfort, delirium, and PONV in infants and young children undergoing strabismus surgery.
Topics: Analgesics; Antiemetics; Delirium; Dexamethasone; Droperidol; Hospitals, University; Humans; Minneso | 2011 |
The effect of ondansetron and intrathecal diamorphine on length of stay after caesarean section: an impact audit cycle.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Female; Heroin; H | 2013 |
Dystonic reaction following anaesthesia.
Topics: Adult; Anesthesia, Dental; Anesthesia, General; Antiemetics; Dystonia; Female; Humans; Ondansetron; | 2004 |
Transient blindness following intravenous ondansetron.
Topics: Adult; Antiemetics; Blindness; Female; Humans; Ondansetron; Postoperative Complications; Postoperati | 2005 |
A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis.
Topics: Adult; Anesthesia, General; Antiemetics; Antipruritics; Female; Humans; Male; Medical Records; Middl | 2007 |
Ondansetron and carpopedal spasm.
Topics: Adult; Diagnosis, Differential; Dystonia; Female; Hand; Humans; Hyperventilation; Leg; Muscle Rigidi | 2008 |
Ondansetron and minor oral surgery.
Topics: Antiemetics; Humans; Nausea; Ondansetron; Placebos; Postoperative Complications; Serotonin Antagonis | 1995 |
Cost-effectiveness analysis of antiemetic therapy for ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Antiemetics; Cost-Benefit Analysis; Costs and Cost Analysis; Droperi | 1995 |
Denial of effective treatment and poor quality of clinical information in placebo controlled trials of ondansetron for postoperative nausea and vomiting: a review of published trials.
Topics: Anesthesia Department, Hospital; Controlled Clinical Trials as Topic; Data Collection; England; Heal | 1995 |
Ondansetron for the prevention of nausea and vomiting.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1995 |
Practical points in the use of ondansetron.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1994 |
[Ondansetron on postoperative nausea and vomiting].
Topics: Abdomen; Adult; Female; Humans; Injections, Intravenous; Male; Middle Aged; Nausea; Ondansetron; Pos | 1994 |
Which routine antiemetic: ondansetron or prochlorperazine?
Topics: Humans; Ondansetron; Postoperative Complications; Prochlorperazine; Vomiting | 1994 |
Surrogate end points. Are they meaningful?
Topics: Antiemetics; Child; Humans; Incidence; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1994 |
Ondansetron for postoperative nausea and vomiting: decisions in the absence of comparative trials.
Topics: Clinical Trials as Topic; Humans; Nausea; Ondansetron; Postoperative Complications; United States; U | 1994 |
Zofran (Ondansetron hydrochloride) injection.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1994 |
Ondansetron and the prevention of postoperative nausea and vomiting.
Topics: Humans; Nausea; Ondansetron; Postoperative Complications; Research Design; Vomiting | 1993 |
Ondansetron versus metoclopramide and droperidol: an unfair comparison.
Topics: Anesthesiology; Droperidol; Humans; Metoclopramide; Nausea; Ondansetron; Postoperative Complications | 1993 |
Placebo controlled trials of ondansetron for postoperative nausea and vomiting.
Topics: Antiemetics; Controlled Clinical Trials as Topic; Humans; Nausea; Ondansetron; Placebos; Postoperati | 1996 |
[Ondansetron in the prevention of postoperative nausea and vomiting in ambulatory surgery].
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Child; Female; Humans; Male; M | 1996 |
[Use of ondansetron for prevention of postoperative nausea and vomiting in major ambulatory surgery].
Topics: Ambulatory Surgical Procedures; Antiemetics; Humans; Nausea; Ondansetron; Postoperative Complication | 1996 |
Study power inadequate to reject ondansetron.
Topics: Antiemetics; Female; Humans; Ondansetron; Postoperative Complications; Statistics as Topic | 1997 |
Can vomiting after squint surgery be prevented?
Topics: Adult; Antiemetics; Child, Preschool; Female; Humans; Male; Metoclopramide; Ondansetron; Postoperati | 1997 |
Prophylactic antiemetics for laparoscopic cholecystectomy: ondansetron versus droperidol plus metoclopramide.
Topics: Antiemetics; Cholecystectomy, Laparoscopic; Droperidol; Drug Therapy, Combination; Humans; Metoclopr | 1997 |
[Acute postoperative pancreatitis, is it associated with the use of ondansetron?].
Topics: Acute Disease; Adolescent; Antiemetics; Humans; Nasal Bone; Ondansetron; Pancreatitis; Postoperative | 1997 |
Impact of covert duplicate publication on meta-analysis: a case study.
Topics: Antiemetics; Duplicate Publications as Topic; Humans; Meta-Analysis as Topic; Ondansetron; Postopera | 1997 |
Correct choice of anti-emetic.
Topics: Antiemetics; Humans; Metoclopramide; Nausea; Ondansetron; Postoperative Complications; Vomiting | 1997 |
The "big little problem" of postoperative nausea and vomiting: do we know the answer yet?
Topics: Antiemetics; Humans; Meta-Analysis as Topic; Nausea; Ondansetron; Outcome Assessment, Health Care; P | 1997 |
The anti-emetic efficacy of a combination of ondansetron and droperidol.
Topics: Antiemetics; Droperidol; Drug Therapy, Combination; Humans; Nausea; Ondansetron; Postoperative Compl | 1998 |
Ondansetron compared with metoclopramide in the treatment of PONV.
Topics: Antiemetics; Drug Therapy, Combination; Humans; Metoclopramide; Nausea; Ondansetron; Postoperative C | 1998 |
Anaphylactoid reaction due to the administration of ondansetron in a pediatric neurosurgical patient.
Topics: Anaphylaxis; Antiemetics; Child; Cranial Fossa, Posterior; Drug Hypersensitivity; Female; Humans; In | 1998 |
Desflurane and nausea following ondansetron premedication.
Topics: Anesthetics, Inhalation; Antiemetics; Desflurane; Humans; Isoflurane; Nausea; Ondansetron; Postopera | 1998 |
Cost effectiveness ratio: an often misunderstood term.
Topics: Cost-Benefit Analysis; Droperidol; Health Care Costs; Humans; Nausea; Ondansetron; Postoperative Com | 1999 |
Masked bleeding posttonsillectomy with ondansetron.
Topics: Antiemetics; Child; Female; Hemorrhage; Humans; Ondansetron; Postoperative Complications; Postoperat | 1999 |
Acute myocardial ischemia after administration of ondansetron hydrochloride.
Topics: Acute Disease; Antiemetics; Electrocardiography; Female; Humans; Injections, Intravenous; Middle Age | 2000 |
The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium.
Topics: Adult; Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Delirium; Female; Humans; Male; Middle | 2000 |
[Ondansetron in the treatment of the pruritus associated with the spinal infusion of opiates].
Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, Spinal; Fentanyl; | 2000 |
The big "little problem".
Topics: Anesthetics; Antiemetics; Causality; Humans; Imidazoles; Nausea; Ondansetron; Postoperative Complica | 1991 |