ondansetron has been researched along with Post-Concussion Syndrome in 3 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Post-Concussion Syndrome: The organic and psychogenic disturbances observed after closed head injuries (HEAD INJURIES, CLOSED). Post-concussion syndrome includes subjective physical complaints (i.e. headache, dizziness), cognitive, emotional, and behavioral changes. These disturbances can be chronic, permanent, or late emerging.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Assess the feasibility of a study evaluating one dose of oral ondansetron to decrease post-concussion symptoms at one week and one month following concussion in children aged 8 to 17 years old." | 5.24 | Ondansetron for pediatric concussion; a pilot study for a randomized controlled trial. ( Beauchamp, MH; Carrière, B; Crevier, L; D'Angelo, A; Gravel, J; Mâsse, B, 2017) |
| "In children presenting to the ED with an acute concussion, ondansetron use was associated with a higher risk of persistent post-concussion symptoms at 1 month." | 3.91 | Association between ondansetron use and symptom persistence in children with concussions: A 5P substudy. ( Beauchamp, MH; Boutis, K; Dubrovsky, AS; Freedman, SB; Gagnon, I; Gravel, J; Momoli, F; Tang, K; Zemek, R, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Standiford, L | 1 |
| O'Daniel, M | 1 |
| Hysell, M | 1 |
| Trigger, C | 1 |
| Gravel, J | 2 |
| Boutis, K | 1 |
| Tang, K | 1 |
| Beauchamp, MH | 2 |
| Freedman, SB | 1 |
| Dubrovsky, AS | 1 |
| Gagnon, I | 1 |
| Momoli, F | 1 |
| Zemek, R | 1 |
| Carrière, B | 1 |
| D'Angelo, A | 1 |
| Crevier, L | 1 |
| Mâsse, B | 1 |
2 trials available for ondansetron and Post-Concussion Syndrome
| Article | Year |
|---|---|
A randomized cohort study of the efficacy of PO magnesium in the treatment of acute concussions in adolescents.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Antiemetics; Brain Concus | 2021 |
Ondansetron for pediatric concussion; a pilot study for a randomized controlled trial.
Topics: Administration, Oral; Adolescent; Brain Concussion; Child; Double-Blind Method; Emergency Service, H | 2017 |
1 other study available for ondansetron and Post-Concussion Syndrome
| Article | Year |
|---|---|
Association between ondansetron use and symptom persistence in children with concussions: A 5P substudy.
Topics: Adolescent; Antiemetics; Brain Concussion; Canada; Child; Child, Preschool; Cohort Studies; Emergenc | 2019 |