ondansetron has been researched along with Poisoning in 6 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Vomiting, retching, or need for rescue antiemetic treatment at 2 h was reported in 39 of 108 patients assigned to the shorter modified protocol compared with 71 of 109 allocated to the standard acetylcysteine regimen (adjusted odds ratio 0·26, 97·5% CI 0·13-0·52; p<0·0001), and in 45 of 109 patients who received ondansetron compared with 65 of 108 allocated placebo (0·41, 0·20-0·80; p=0·003)." | 9.19 | Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. ( Bateman, DN; Butcher, I; Cooper, JG; Coyle, J; Dear, JW; Eddleston, M; Gray, A; Lewis, SC; Rodriguez, A; Sandilands, EA; Thanacoody, HK; Thomas, SH; Veiraiah, A; Vliegenthart, AD; Webb, DJ, 2014) |
| "We sought to compare antiemetic use after acetaminophen poisoning in patients treated with oral or intravenous (IV) N-acetylcysteine (NAC)." | 7.74 | Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization? ( Bird, SB; Donovan, JL; Miller, MA; Navarro, M, 2007) |
| "We present a 17-year-old girl who developed persistent vomiting following acetaminophen overdose." | 7.68 | Ondansetron to prevent emesis following N-acetylcysteine for acetaminophen intoxication. ( Deshpande, JK; Gregory, DF; Tobias, JD, 1992) |
| " Vomiting, retching, or need for rescue antiemetic treatment at 2 h was reported in 39 of 108 patients assigned to the shorter modified protocol compared with 71 of 109 allocated to the standard acetylcysteine regimen (adjusted odds ratio 0·26, 97·5% CI 0·13-0·52; p<0·0001), and in 45 of 109 patients who received ondansetron compared with 65 of 108 allocated placebo (0·41, 0·20-0·80; p=0·003)." | 5.19 | Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. ( Bateman, DN; Butcher, I; Cooper, JG; Coyle, J; Dear, JW; Eddleston, M; Gray, A; Lewis, SC; Rodriguez, A; Sandilands, EA; Thanacoody, HK; Thomas, SH; Veiraiah, A; Vliegenthart, AD; Webb, DJ, 2014) |
| "We sought to compare antiemetic use after acetaminophen poisoning in patients treated with oral or intravenous (IV) N-acetylcysteine (NAC)." | 3.74 | Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization? ( Bird, SB; Donovan, JL; Miller, MA; Navarro, M, 2007) |
| "We present a 17-year-old girl who developed persistent vomiting following acetaminophen overdose." | 3.68 | Ondansetron to prevent emesis following N-acetylcysteine for acetaminophen intoxication. ( Deshpande, JK; Gregory, DF; Tobias, JD, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bateman, DN | 1 |
| Dear, JW | 1 |
| Thanacoody, HK | 1 |
| Thomas, SH | 1 |
| Eddleston, M | 1 |
| Sandilands, EA | 1 |
| Coyle, J | 1 |
| Cooper, JG | 1 |
| Rodriguez, A | 1 |
| Butcher, I | 1 |
| Lewis, SC | 1 |
| Vliegenthart, AD | 1 |
| Veiraiah, A | 1 |
| Webb, DJ | 1 |
| Gray, A | 1 |
| George, M | 1 |
| Al-Duaij, N | 1 |
| O'Donnell, KA | 1 |
| Shannon, MW | 1 |
| Miller, MA | 1 |
| Navarro, M | 1 |
| Bird, SB | 1 |
| Donovan, JL | 1 |
| Forster, ER | 1 |
| Palmer, JL | 1 |
| Sage, TA | 1 |
| Jones, WN | 1 |
| Clark, RF | 1 |
| Tobias, JD | 1 |
| Gregory, DF | 1 |
| Deshpande, JK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Trial to Assess the Effectiveness of Pre-treatment With Ondansetron at Reducing Nausea and Vomiting in Patients Treated With Either the Conventional Regimen or a Modified Regimen of Acetylcysteine for Paracetamol Poisoning[NCT01050270] | Phase 4 | 222 participants (Actual) | Interventional | 2010-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ondansetron and Poisoning
| Article | Year |
|---|---|
Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.
Topics: Acetaminophen; Acetylcysteine; Adult; Aged; Alanine Transaminase; Antiemetics; Double-Blind Method; | 2014 |
5 other studies available for ondansetron and Poisoning
| Article | Year |
|---|---|
Obtundation and seizure following ondansetron overdose in an infant.
Topics: Antiemetics; Humans; Infant; Male; Ondansetron; Poisoning; Seizures; Treatment Outcome; Unconsciousn | 2008 |
Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization?
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antidotes; Ant | 2007 |
Comment: Ondansetron for treating nausea and vomiting in the poisoned patient.
Topics: Humans; Ipecac; Nausea; Ondansetron; Poisoning; Vomiting | 1994 |
Ondansetron in the treatment of intractable nausea associated with theophylline toxicity.
Topics: Adult; Delayed-Action Preparations; Humans; Male; Nausea; Ondansetron; Poisoning; Theophylline; Vomi | 1993 |
Ondansetron to prevent emesis following N-acetylcysteine for acetaminophen intoxication.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Female; Humans; Infusions, Intravenous; Ipecac; Ondansetr | 1992 |