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ondansetron and Panic Disorder

ondansetron has been researched along with Panic Disorder in 3 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"Pentagastrin, a cholecystokinin (CCK) agonist, produces anxiety and panic in patients with panic disorder and social phobia."9.08Effects of the 5-HT3 antagonist, ondansetron, on the behavioral and physiological effects of pentagastrin in patients with panic disorder and social phobia. ( Geraci, M; McCann, UD; Morgan, CM; Murphy, DL; Post, RM; Slate, SO, 1997)
"Pentagastrin, a cholecystokinin (CCK) agonist, produces anxiety and panic in patients with panic disorder and social phobia."5.08Effects of the 5-HT3 antagonist, ondansetron, on the behavioral and physiological effects of pentagastrin in patients with panic disorder and social phobia. ( Geraci, M; McCann, UD; Morgan, CM; Murphy, DL; Post, RM; Slate, SO, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schneier, FR1
Garfinkel, R1
Kennedy, B1
Campeas, R1
Fallon, B1
Marshall, R1
O'Donnell, L1
Hogan, T1
Liebowitz, MR1
McCann, UD1
Morgan, CM1
Geraci, M1
Slate, SO1
Murphy, DL1
Post, RM1
Dépôt, M1
Merani, S1
Bradwejn, J1
Mukherjee, J1
Caillé, J1
Gutkowska, J1
Caillé, G1

Trials

2 trials available for ondansetron and Panic Disorder

ArticleYear
Effects of the 5-HT3 antagonist, ondansetron, on the behavioral and physiological effects of pentagastrin in patients with panic disorder and social phobia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 17, Issue:6

    Topics: Adult; Behavior; Female; Hemodynamics; Hormones; Humans; Interpersonal Relations; Male; Ondansetron;

1997
Effect of oral ondansetron on total cholecystokinin plasma levels following CCK-4 panic challenge procedure in healthy men.
    Journal of psychiatry & neuroscience : JPN, 1998, Volume: 23, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Cholecystokinin; Double-Blind Method;

1998

Other Studies

1 other study available for ondansetron and Panic Disorder

ArticleYear
Ondansetron in the treatment of panic disorder.
    Anxiety, 1996, Volume: 2, Issue:4

    Topics: Administration, Oral; Adult; Agoraphobia; Female; Humans; Male; Middle Aged; Ondansetron; Panic Diso

1996