Page last updated: 2024-11-01

ondansetron and Pancreatic Neoplasms

ondansetron has been researched along with Pancreatic Neoplasms in 6 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to evaluate the role of ramosetron for the prevention of chemoradiotherapy-induced nausea and vomiting (CRINV) in patients receiving upper abdominal irradiation with concurrent 5-fluorouracil chemotherapy."7.75Ramosetron for the prevention of nausea and vomiting during 5-fluorouracil-based chemoradiotherapy for pancreatico-biliary cancer. ( Bang, YJ; Chie, EK; Ha, SW; Im, SA; Jang, JY; Kim, K; Kim, SW; Kim, TY; Oh, DY, 2009)
"The aim of the study was to evaluate the role of ramosetron for the prevention of chemoradiotherapy-induced nausea and vomiting (CRINV) in patients receiving upper abdominal irradiation with concurrent 5-fluorouracil chemotherapy."3.75Ramosetron for the prevention of nausea and vomiting during 5-fluorouracil-based chemoradiotherapy for pancreatico-biliary cancer. ( Bang, YJ; Chie, EK; Ha, SW; Im, SA; Jang, JY; Kim, K; Kim, SW; Kim, TY; Oh, DY, 2009)
"Case 3, a 44-year-old woman, having breast cancer treated with 5-fluorouracil, cyclophosphamide, and epirubicin developed an MPR after the second chemotherapy treatment."1.35Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs. ( Barbaud, A; Bursztejn, AC; Cuny, JF; Schmutz, JL; Tréchot, P, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, K1
Chie, EK1
Jang, JY1
Kim, SW1
Oh, DY1
Im, SA1
Kim, TY1
Bang, YJ1
Ha, SW1
Bousquet, PJ1
Co-Minh, HB1
Demoly, P1
Bursztejn, AC1
Tréchot, P1
Cuny, JF1
Schmutz, JL1
Barbaud, A1
Ishizuka, J1
Hsieh, AC1
Townsend, CM1
Thompson, JC1
Delahunt, JW1
Burgess, C1
Bott, V1
Jacobsen, MB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase III Prospective Randomized Trial Comparing Ramosetron Versus Ondansetron for Radiotherapy Induced Nausea and Vomiting in the Treatment of Gastrointestinal Cancer[NCT00971399]Phase 3172 participants (Anticipated)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for ondansetron and Pancreatic Neoplasms

ArticleYear
Ramosetron for the prevention of nausea and vomiting during 5-fluorouracil-based chemoradiotherapy for pancreatico-biliary cancer.
    Japanese journal of clinical oncology, 2009, Volume: 39, Issue:2

    Topics: Adult; Aged; Antiemetics; Benzimidazoles; Biliary Tract Neoplasms; Chemotherapy, Adjuvant; Female; F

2009
Isolated urticaria to ondansetron and successful treatment with granisetron.
    Allergy, 2005, Volume: 60, Issue:4

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Drug Hypersensitivity; Granisetr

2005
Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs.
    Contact dermatitis, 2008, Volume: 58, Issue:6

    Topics: Adult; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Cross Reactions; Drug Eruptions; Female

2008
Effect of 5-HT3 receptor antagonist (ondansetron) on functioning human pancreatic carcinoid cells.
    Surgical oncology, 1993, Volume: 2, Issue:4

    Topics: Calcium; Carcinoid Tumor; Cell Division; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Hydro

1993
Ondansetron and VIPoma.
    The New Zealand medical journal, 1993, Jun-23, Volume: 106, Issue:958

    Topics: Adult; Humans; Male; Nausea; Ondansetron; Pancreatic Neoplasms; Vipoma

1993
Ondansetron in carcinoid syndrome.
    Lancet (London, England), 1992, Jul-18, Volume: 340, Issue:8812

    Topics: Aged; Carcinoid Tumor; Humans; Imidazoles; Male; Ondansetron; Pancreatic Neoplasms; Serotonin Antago

1992