Page last updated: 2024-11-01

ondansetron and Neuroleptic Malignant Syndrome

ondansetron has been researched along with Neuroleptic Malignant Syndrome in 1 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brantley, E1
Cohn, J1
Babu, K1

Other Studies

1 other study available for ondansetron and Neuroleptic Malignant Syndrome

ArticleYear
Case files of the program in medical toxicology at brown university: amantadine withdrawal and the neuroleptic malignant syndrome.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Diagnosis, Differential; Drug Therapy, Combination; Female; Fluid

2009