ondansetron has been researched along with Multiple Sclerosis in 3 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two young women with chronic nausea and vertigo caused by multiple sclerosis responded to the introduction and maintenance of the 5HT3 receptor antagonist, ondansetron." | 7.70 | Ondansetron in multiple sclerosis. ( Macleod, AD, 2000) |
| "Cerebellar tremor is a frequent and disabling symptom in multiple sclerosis (MS) patients." | 6.70 | Failure of ondansetron in treating cerebellar tremor in MS patients--an open-label pilot study. ( Buhmann, C; Gbadamosi, J; Heesen, C; Moench, A, 2001) |
| "Two young women with chronic nausea and vertigo caused by multiple sclerosis responded to the introduction and maintenance of the 5HT3 receptor antagonist, ondansetron." | 3.70 | Ondansetron in multiple sclerosis. ( Macleod, AD, 2000) |
| "Cerebellar tremor is a frequent and disabling symptom in multiple sclerosis (MS) patients." | 2.70 | Failure of ondansetron in treating cerebellar tremor in MS patients--an open-label pilot study. ( Buhmann, C; Gbadamosi, J; Heesen, C; Moench, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rice, GP | 1 |
| Ebers, GC | 1 |
| Macleod, AD | 1 |
| Gbadamosi, J | 1 |
| Buhmann, C | 1 |
| Moench, A | 1 |
| Heesen, C | 1 |
1 trial available for ondansetron and Multiple Sclerosis
| Article | Year |
|---|---|
Failure of ondansetron in treating cerebellar tremor in MS patients--an open-label pilot study.
Topics: Adult; Cerebellar Diseases; Female; Humans; Injections, Intravenous; Male; Multiple Sclerosis; Ondan | 2001 |
2 other studies available for ondansetron and Multiple Sclerosis
| Article | Year |
|---|---|
Ondansetron for intractable vertigo complicating acute brainstem disorders.
Topics: Acute Disease; Adult; Brain Diseases; Brain Stem; Humans; Middle Aged; Multiple Sclerosis; Ondansetr | 1995 |
Ondansetron in multiple sclerosis.
Topics: Adult; Female; Humans; Multiple Sclerosis; Nausea; Ondansetron; Palliative Care; Serotonin Antagonis | 2000 |