Page last updated: 2024-11-01

ondansetron and Multiple Myeloma

ondansetron has been researched along with Multiple Myeloma in 4 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Forty-one patients with multiple myeloma were treated with a novel stem cell mobilisation regimen."6.70Dexamethasone, paclitaxel, etoposide, cyclophosphamide (d-TEC) and G-CSF for stem cell mobilisation in multiple myeloma. ( Bilgrami, S; Bona, RD; Clive, J; Edwards, RL; Fox, J; Furlong, F; Li, Z; Naqvi, B; Shaikh, A; Tutschka, PJ, 2001)
"Forty-one patients with multiple myeloma were treated with a novel stem cell mobilisation regimen."2.70Dexamethasone, paclitaxel, etoposide, cyclophosphamide (d-TEC) and G-CSF for stem cell mobilisation in multiple myeloma. ( Bilgrami, S; Bona, RD; Clive, J; Edwards, RL; Fox, J; Furlong, F; Li, Z; Naqvi, B; Shaikh, A; Tutschka, PJ, 2001)
"Ondansetron is a highly effective non-sedative antiemetic that justifies further assessment in combination with other antiemetics in patients receiving cytotoxic drugs associated with the production of severe nausea and vomiting."1.28Ondansetron--a new safe and effective antiemetic in patients receiving high-dose melphalan. ( Butcher, ME; Gore, ME; McElwain, TJ; Selby, PJ; Viner, CV; Wootton, CM; Zulian, GB, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mathews, HG1
Tancil, CG1
Lacerda, JF1
Martins, C1
Carmo, JA1
Lourenço, MF1
Araújo Pereira, ME1
Rodrigues, A1
Juncal, C1
Lacerda, JM1
Bilgrami, S1
Bona, RD1
Edwards, RL1
Li, Z1
Naqvi, B1
Shaikh, A1
Furlong, F1
Fox, J1
Clive, J1
Tutschka, PJ1
Viner, CV1
Selby, PJ1
Zulian, GB1
Gore, ME1
Butcher, ME1
Wootton, CM1
McElwain, TJ1

Trials

2 trials available for ondansetron and Multiple Myeloma

ArticleYear
Randomized trial of ondansetron, granisetron, and tropisetron in the prevention of acute nausea and vomiting.
    Transplantation proceedings, 2000, Volume: 32, Issue:8

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Femal

2000
Dexamethasone, paclitaxel, etoposide, cyclophosphamide (d-TEC) and G-CSF for stem cell mobilisation in multiple myeloma.
    Bone marrow transplantation, 2001, Volume: 28, Issue:2

    Topics: Adult; Aged; Antiemetics; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protoco

2001

Other Studies

2 other studies available for ondansetron and Multiple Myeloma

ArticleYear
Extrapyramidal reaction caused by ondansetron.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:2

    Topics: Aged; Antiemetics; Antineoplastic Agents; Basal Ganglia Diseases; Humans; Male; Multiple Myeloma; Na

1996
Ondansetron--a new safe and effective antiemetic in patients receiving high-dose melphalan.
    Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:6

    Topics: Administration, Oral; Antiemetics; Drug Administration Schedule; Drug Evaluation; Female; Humans; Im

1990