ondansetron has been researched along with Malignant Melanoma in 8 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients received an anti-nausea regimen of dexamethasone with ondansetron or granisetron." | 9.09 | The effect of tamoxifen and cisplatin on the disease-free and overall survival of patients with high risk malignant melanoma. ( Baron, PL; Cole, DJ; Maize, JC; McClay, EF; McClay, ME; Metcalf, JS; Monroe, L; O'Brien, PH, 2000) |
| "The anti-emetic effect of ondansetron in cisplatin induced nausea and vomiting was studied in a randomized cross-over trial in 52 patients." | 9.07 | [Anti-emetic effect of ondansetron in cisplatin induced nausea and vomiting--a randomized clinical trial]. ( Zeng, WY, 1992) |
| "The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin." | 7.68 | Efficacy of ondansetron against nausea and vomiting caused by dacarbazine-containing chemotherapy. ( Hodges, C; Legha, SS; Ring, S, 1992) |
| "Delayed emesis has not been seen during the antiemetic therapies." | 6.67 | [Nausea and vomiting in cytostatic therapy of melanoma patients with the use of metoclopramide and corticosteroid or ondansetron]. ( Baki, M; Czeglédi, F, 1994) |
| " Patients received an anti-nausea regimen of dexamethasone with ondansetron or granisetron." | 5.09 | The effect of tamoxifen and cisplatin on the disease-free and overall survival of patients with high risk malignant melanoma. ( Baron, PL; Cole, DJ; Maize, JC; McClay, EF; McClay, ME; Metcalf, JS; Monroe, L; O'Brien, PH, 2000) |
| "The anti-emetic effect of ondansetron in cisplatin induced nausea and vomiting was studied in a randomized cross-over trial in 52 patients." | 5.07 | [Anti-emetic effect of ondansetron in cisplatin induced nausea and vomiting--a randomized clinical trial]. ( Zeng, WY, 1992) |
| " We describe a patient with metastatic melanoma who developed a multifocal FDE to paracetamol, tropisetron and ondansetron during chemoimmunotherapy with interleukin 2 (IL-2) and dacarbazine." | 3.70 | Multifocal fixed drug eruption to paracetamol, tropisetron and ondansetron induced by interleukin 2. ( Bernand, S; Burg, G; Dummer, R; Scheidegger, EP, 2000) |
| "The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin." | 3.68 | Efficacy of ondansetron against nausea and vomiting caused by dacarbazine-containing chemotherapy. ( Hodges, C; Legha, SS; Ring, S, 1992) |
| "Delayed emesis has not been seen during the antiemetic therapies." | 2.67 | [Nausea and vomiting in cytostatic therapy of melanoma patients with the use of metoclopramide and corticosteroid or ondansetron]. ( Baki, M; Czeglédi, F, 1994) |
| "Ondansetron or droperidol was given intravenously, 30 min prior to the first dose of IL-2 and then every 8 h for the duration of IL-2 treatment." | 2.67 | A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2. ( Cole, DJ; Kim, H; Rosenberg, SA; Steinberg, SM; Weber, JS, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Barzegar-Fallah, A | 1 |
| Alimoradi, H | 1 |
| Dunlop, JL | 1 |
| Torbati, E | 1 |
| Baird, SK | 1 |
| Czeglédi, F | 1 |
| Baki, M | 1 |
| Kim, H | 1 |
| Rosenberg, SA | 1 |
| Steinberg, SM | 1 |
| Cole, DJ | 2 |
| Weber, JS | 1 |
| Iglesias, ME | 1 |
| España, A | 1 |
| Redondo, P | 1 |
| Quintanilla, E | 1 |
| McClay, EF | 1 |
| McClay, ME | 1 |
| Monroe, L | 1 |
| Baron, PL | 1 |
| O'Brien, PH | 1 |
| Metcalf, JS | 1 |
| Maize, JC | 1 |
| Bernand, S | 1 |
| Scheidegger, EP | 1 |
| Dummer, R | 1 |
| Burg, G | 1 |
| Legha, SS | 1 |
| Hodges, C | 1 |
| Ring, S | 1 |
| Zeng, WY | 1 |
4 trials available for ondansetron and Malignant Melanoma
| Article | Year |
|---|---|
[Nausea and vomiting in cytostatic therapy of melanoma patients with the use of metoclopramide and corticosteroid or ondansetron].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Huma | 1994 |
A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2.
Topics: Adult; Aged; Carcinoma, Renal Cell; Droperidol; Female; Humans; Interleukin-2; Lymphoma, Non-Hodgkin | 1994 |
The effect of tamoxifen and cisplatin on the disease-free and overall survival of patients with high risk malignant melanoma.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Ci | 2000 |
[Anti-emetic effect of ondansetron in cisplatin induced nausea and vomiting--a randomized clinical trial].
Topics: Adult; Aged; Antiemetics; Breast Neoplasms; Cisplatin; Female; Humans; Lung Neoplasms; Male; Melanom | 1992 |
4 other studies available for ondansetron and Malignant Melanoma
| Article | Year |
|---|---|
Serotonin type-3 receptor antagonists selectively kill melanoma cells through classical apoptosis, microtubule depolymerisation, ERK activation, and NF-κB downregulation.
Topics: Antiemetics; Apoptosis; Down-Regulation; Humans; Melanoma; Molecular Docking Simulation; NF-kappa B; | 2023 |
Fixed drug eruption secondary to ondansetron.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Eruptio | 1995 |
Multifocal fixed drug eruption to paracetamol, tropisetron and ondansetron induced by interleukin 2.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Eruptions; Drug Interactions; Huma | 2000 |
Efficacy of ondansetron against nausea and vomiting caused by dacarbazine-containing chemotherapy.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dac | 1992 |