ondansetron has been researched along with Malignant Carcinoid Syndrome in 6 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Malignant Carcinoid Syndrome: A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of ondansetron, a selective serotonin 5-HT3 receptor antagonist, is well established in patients with nausea and vomiting associated with cancer chemotherapy, radiotherapy or anaesthesia and surgery." | 4.79 | Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications. ( Markham, A; Wilde, MI, 1996) |
| "Flushing was not affected." | 1.30 | Effects of ondansetron on gastrointestinal symptoms in carcinoid syndrome. ( de Vries, EG; Kema, IP; Kleibeuker, JH; Leijsma, MK; Wymenga, AN, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiesewetter, B | 1 |
| Duan, H | 1 |
| Lamm, W | 1 |
| Haug, A | 1 |
| Riss, P | 1 |
| Selberherr, A | 1 |
| Scheuba, C | 1 |
| Raderer, M | 1 |
| Schwörer, H | 1 |
| Münke, H | 1 |
| Stöckmann, F | 1 |
| Ramadori, G | 1 |
| Wilde, MI | 1 |
| Markham, A | 1 |
| Wymenga, AN | 1 |
| de Vries, EG | 1 |
| Leijsma, MK | 1 |
| Kema, IP | 1 |
| Kleibeuker, JH | 1 |
| Platt, AJ | 1 |
| Heddle, RM | 1 |
| Rake, MO | 1 |
| Smedley, H | 1 |
| Buhl, C | 1 |
| Fibbe, C | 1 |
| Frenzel, H | 1 |
1 review available for ondansetron and Malignant Carcinoid Syndrome
| Article | Year |
|---|---|
Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications.
Topics: Animals; Antiemetics; Brain; Colonic Diseases, Functional; Digestive System; Drug Interactions; Drug | 1996 |
5 other studies available for ondansetron and Malignant Carcinoid Syndrome
| Article | Year |
|---|---|
Oral Ondansetron Offers Effective Antidiarrheal Activity for Carcinoid Syndrome Refractory to Somatostatin Analogs.
Topics: Administration, Oral; Aged; Antidiarrheals; Female; Humans; Male; Malignant Carcinoid Syndrome; Midd | 2019 |
Treatment of diarrhea in carcinoid syndrome with ondansetron, tropisetron, and clonidine.
Topics: Antiemetics; Clonidine; Diarrhea; Humans; Indoles; Male; Malignant Carcinoid Syndrome; Middle Aged; | 1995 |
Effects of ondansetron on gastrointestinal symptoms in carcinoid syndrome.
Topics: Adult; Aged; Diarrhea; Flushing; Gastric Emptying; Humans; Malignant Carcinoid Syndrome; Middle Aged | 1998 |
Ondansetron in carcinoid syndrome.
Topics: Humans; Imidazoles; Male; Malignant Carcinoid Syndrome; Middle Aged; Ondansetron; Palliative Care; S | 1992 |
[Ondansetron in carcinoid syndrome].
Topics: Administration, Oral; Aged; Female; Humans; Malignant Carcinoid Syndrome; Ondansetron; Time Factors | 1992 |