Page last updated: 2024-11-01

ondansetron and Lymphoma, Non-Hodgkin

ondansetron has been researched along with Lymphoma, Non-Hodgkin in 7 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

Research Excerpts

ExcerptRelevanceReference
" The overall incidence of adverse events was similar between the two treatment groups (pā€‰>ā€‰."6.84Efficacy and safety of triple therapy with aprepitant, ondansetron, and prednisone for preventing nausea and vomiting induced by R-CEOP or CEOP chemotherapy regimen for non-Hodgkin lymphoma: a phase 2 open-label, randomized comparative trial. ( Song, Z; Wang, H; Yang, F; Zhang, H; Zhang, M; Zhao, K, 2017)
"We performed a clinical study of a triple-drug combination to evaluate its efficacy to prevent both acute and delayed emesis after high-dose chemotherapy with BEAM (BCNU [carmustine]+etoposide+ARA-C [cytarabine]+melphalan) before hematopoietic stem cell transplantation (HSCT) by comparison with a historical control group of patients treated with dexamethasone (dex) and ondansetron or palonosetron."5.15A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation. ( Barzal, J; Gawronski, K; Mlot, B; Oborska, S; Pielichowski, W; Rzepecki, P; Wasko-Grabowska, A, 2011)
" The overall incidence of adverse events was similar between the two treatment groups (pā€‰>ā€‰."2.84Efficacy and safety of triple therapy with aprepitant, ondansetron, and prednisone for preventing nausea and vomiting induced by R-CEOP or CEOP chemotherapy regimen for non-Hodgkin lymphoma: a phase 2 open-label, randomized comparative trial. ( Song, Z; Wang, H; Yang, F; Zhang, H; Zhang, M; Zhao, K, 2017)
"Ondansetron or droperidol was given intravenously, 30 min prior to the first dose of IL-2 and then every 8 h for the duration of IL-2 treatment."2.67A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2. ( Cole, DJ; Kim, H; Rosenberg, SA; Steinberg, SM; Weber, JS, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Song, Z1
Wang, H1
Zhang, H1
Zhao, K1
Zhang, M1
Yang, F1
Pielichowski, W1
Barzal, J1
Gawronski, K1
Mlot, B1
Oborska, S1
Wasko-Grabowska, A1
Rzepecki, P1
Colquhoun, JP1
Kim, H1
Rosenberg, SA1
Steinberg, SM1
Cole, DJ1
Weber, JS1
Fedele, P1
Spina, M1
Valentini, M1
Collini, D1
Lucia, C1
Manicone, M1
Tirelli, U1
Wong, ET1
Portlock, CS1
O'Brien, JP1
DeAngelis, LM1
Gibbs, SJ1
Cassoni, AM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aprepitant- and Olanzapine- Containing Regimens for Prevention of Acute and Delayed Nausea and Vomiting Associated With High Dose Melphalan and BEAM in Autologous Stem Cell Transplant Patients[NCT02939287]Phase 3429 participants (Actual)Interventional2017-09-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for ondansetron and Lymphoma, Non-Hodgkin

ArticleYear
Efficacy and safety of triple therapy with aprepitant, ondansetron, and prednisone for preventing nausea and vomiting induced by R-CEOP or CEOP chemotherapy regimen for non-Hodgkin lymphoma: a phase 2 open-label, randomized comparative trial.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:4

    Topics: Activities of Daily Living; Adult; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Drug

2017
A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation.
    Transplantation proceedings, 2011, Volume: 43, Issue:8

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carmustine; Cytarabine; Dex

2011
A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2.
    Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy, 1994, Volume: 16, Issue:1

    Topics: Adult; Aged; Carcinoma, Renal Cell; Droperidol; Female; Humans; Interleukin-2; Lymphoma, Non-Hodgkin

1994
Ondansetron versus granisetron in the prevention of chemotherapy-induced nausea and vomiting.
    Cancer, 1995, Aug-01, Volume: 76, Issue:3

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Granisetron; Humans; Lymphoma, AIDS-Related; Lympho

1995
Chemosensitive epidural spinal cord disease in non-Hodgkins lymphoma.
    Neurology, 1996, Volume: 46, Issue:6

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dox

1996
A pilot study to evaluate the cost-effectiveness of ondansetron and granisetron in fractionated total body irradiation.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:3

    Topics: Administration, Oral; Antiemetics; Bone Marrow Transplantation; Cost-Benefit Analysis; Drug Administ

1996

Other Studies

1 other study available for ondansetron and Lymphoma, Non-Hodgkin

ArticleYear
The mark of Zorro.
    Australian family physician, 1994, Volume: 23, Issue:7

    Topics: Acyclovir; Aged; Anecdotes as Topic; Family Practice; Female; Herpes Zoster Oticus; Humans; Leukemia

1994