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ondansetron and Kidney Failure, Chronic

ondansetron has been researched along with Kidney Failure, Chronic in 6 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Pregabalin is an effective alternative for treatment of uraemic pruritus."9.20Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015)
" We treated the pain of acute arthritis with the specific 5-hydroxytryptamine subtype 3 receptor antagonist ondansetron."7.69Treatment of acute gouty arthritis with the 5-hydroxytryptamine antagonist ondansetron. ( Ramadori, G; Schwörer, H, 1994)
"Pruritus is a common, unpleasant symptom of uremic patients."6.69Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998)
"Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron."5.32Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004)
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy."5.28Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992)
"Pregabalin is an effective alternative for treatment of uraemic pruritus."5.20Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015)
" We treated the pain of acute arthritis with the specific 5-hydroxytryptamine subtype 3 receptor antagonist ondansetron."3.69Treatment of acute gouty arthritis with the 5-hydroxytryptamine antagonist ondansetron. ( Ramadori, G; Schwörer, H, 1994)
"Pruritus is a common, unpleasant symptom of uremic patients."2.69Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998)
"Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron."1.32Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004)
"During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy."1.28Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. ( Childs, A; Coates, AS; Cox, K; Forsyth, C; Grygiel, JJ; Joshua, DE; McNeil, E, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yue, J1
Jiao, S1
Xiao, Y1
Ren, W1
Zhao, T1
Meng, J1
Murphy, M1
Reaich, D1
Pai, P1
Finn, P1
Carmichael, AJ1
Deshpande, PV1
Schwörer, H1
Ramadori, G1
Balaskas, EV1
Bamihas, GI1
Karamouzis, M1
Voyiatzis, G1
Tourkantonis, A1
Coates, AS1
Childs, A1
Cox, K1
Forsyth, C1
Joshua, DE1
McNeil, E1
Grygiel, JJ1

Trials

3 trials available for ondansetron and Kidney Failure, Chronic

ArticleYear
Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study.
    International urology and nephrology, 2015, Volume: 47, Issue:1

    Topics: Adult; Aged; Analgesics; Antipruritics; Double-Blind Method; Drug Therapy, Combination; Female; gamm

2015
A randomized, placebo-controlled, double-blind trial of ondansetron in renal itch.
    The British journal of dermatology, 2003, Volume: 148, Issue:2

    Topics: Antipruritics; Double-Blind Method; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Onda

2003
Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients.
    Nephron, 1998, Volume: 78, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Histamine; Humans; Kidney Failure, Chr

1998

Other Studies

3 other studies available for ondansetron and Kidney Failure, Chronic

ArticleYear
Ondansetron for paediatric uraemic pruritus: a case report.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:6

    Topics: Adolescent; Antipruritics; Female; Humans; Kidney Failure, Chronic; Ondansetron; Peritoneal Dialysis

2004
Treatment of acute gouty arthritis with the 5-hydroxytryptamine antagonist ondansetron.
    The Clinical investigator, 1994, Volume: 72, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Colchicine; Contraindications; Eso

1994
Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Female; Humans; Kid

1992