ondansetron has been researched along with Injuries, Radiation in 9 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ondansetron is a cost effective and safe antiemetic in children receiving chemotherapy and total body irradiation, minimises weight loss on treatment and enables outpatient chemotherapy in some cases." | 5.28 | Ondansetron antiemetic therapy for chemotherapy and radiotherapy induced vomiting in children. ( Abbott, GD; Robinson, BA; Sullivan, MJ, 1992) |
| "67% of patients given ondansetron had complete control of emesis compared with 45% of patients with placebo (P < 0." | 5.08 | A randomised placebo controlled study with ondansetron in patients undergoing fractionated radiotherapy. ( Franzén, L; Hagberg, H; Henriksson, R; Jakobsson, M; Lomberg, H; Nyman, J; Nyth, AL; Sorbe, B, 1996) |
| "The aim of this study was to determine the mechanism of action of radiation-induced emesis by determining the incidence of radiation-induced emesis following hemibody irradiation; the effects of specific antiemetics especially ondansetron, a 5-hydroxytryptamine receptor antagonist, and to determine the relationship between radiation-induced emesis and serotonin (5-hydroxytryptamine) through its active metabolite, 5-hydroxyindoleacetic acid (5-HIAA)." | 5.07 | On the mechanism of radiation-induced emesis: the role of serotonin. ( Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW, 1994) |
| "Ondansetron is a 5-HT3 receptor antagonist which has shown activity in the prevention of nausea and vomiting resulting from cytotoxic therapy." | 3.76 | Clinical studies with ondansetron in the control of radiation-induced emesis. ( Priestman, TJ, 1989) |
| "85 patients with differentiated thyroid cancer who received 131I." | 2.79 | Management of gastrointestinal complaints in differentiated thyroid cancer patients treated with (131)I: comparison of the efficacy of pantoprazole, metoclopramide, and ondansetron - a randomized clinical trial. ( Asli, IN; Assadi, M; Baharfar, N; Delavari, S; Fatholahi, L; Javadi, H; Mirzababaee, M; Motazdian, M; Naghshine, R; Seifollahi, S; Shafiei, B; Tabeie, F, 2014) |
| "Ondansetron (GR 38032F) is a highly selective 5-HT3 receptor antagonist, one of a new class of compounds which may have several therapeutic applications." | 2.38 | Ondansetron. Therapeutic use as an antiemetic. ( Heel, RC; Milne, RJ, 1991) |
| "Radiation sickness is frequently observed in total body irradiation (TBI)." | 1.33 | Ondansetron, dexamethasone and an NK1 antagonist block radiation sickness in mice. ( Furuya, T; Nohara, K; Yamamoto, K; Yamatodani, A, 2005) |
| "Ondansetron is a cost effective and safe antiemetic in children receiving chemotherapy and total body irradiation, minimises weight loss on treatment and enables outpatient chemotherapy in some cases." | 1.28 | Ondansetron antiemetic therapy for chemotherapy and radiotherapy induced vomiting in children. ( Abbott, GD; Robinson, BA; Sullivan, MJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mirzababaee, M | 1 |
| Shafiei, B | 1 |
| Seifollahi, S | 1 |
| Motazdian, M | 1 |
| Fatholahi, L | 1 |
| Delavari, S | 1 |
| Naghshine, R | 1 |
| Baharfar, N | 1 |
| Tabeie, F | 1 |
| Javadi, H | 1 |
| Assadi, M | 1 |
| Asli, IN | 1 |
| Yamamoto, K | 1 |
| Nohara, K | 1 |
| Furuya, T | 1 |
| Yamatodani, A | 1 |
| Scarantino, CW | 1 |
| Ornitz, RD | 1 |
| Hoffman, LG | 1 |
| Anderson, RF | 1 |
| Franzén, L | 1 |
| Nyman, J | 1 |
| Hagberg, H | 1 |
| Jakobsson, M | 1 |
| Sorbe, B | 1 |
| Nyth, AL | 1 |
| Lomberg, H | 1 |
| Henriksson, R | 1 |
| Sullivan, MJ | 1 |
| Abbott, GD | 1 |
| Robinson, BA | 1 |
| Milne, RJ | 1 |
| Heel, RC | 1 |
| Erben, M | 1 |
| Kidgell, AE | 1 |
| Butcher, ME | 1 |
| Brown, GW | 1 |
| Priestman, TJ | 1 |
3 reviews available for ondansetron and Injuries, Radiation
| Article | Year |
|---|---|
Ondansetron. Therapeutic use as an antiemetic.
Topics: Antiemetics; Antineoplastic Agents; Humans; Imidazoles; Metoclopramide; Nausea; Ondansetron; Radiati | 1991 |
Antiemetic control: 5-HT3 antagonists: review of clinical results, with particular emphasis on ondansetron.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Granisetron; Headache; Human | 1990 |
Clinical studies with ondansetron in the control of radiation-induced emesis.
Topics: Antiemetics; Humans; Imidazoles; Ondansetron; Pilot Projects; Radiation Injuries; Randomized Control | 1989 |
4 trials available for ondansetron and Injuries, Radiation
| Article | Year |
|---|---|
Management of gastrointestinal complaints in differentiated thyroid cancer patients treated with (131)I: comparison of the efficacy of pantoprazole, metoclopramide, and ondansetron - a randomized clinical trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antiemetics; Female; Gastrointestinal Diseases; Humans; Iod | 2014 |
On the mechanism of radiation-induced emesis: the role of serotonin.
Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic | 1994 |
A randomised placebo controlled study with ondansetron in patients undergoing fractionated radiotherapy.
Topics: Abdomen; Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; N | 1996 |
Clinical studies with ondansetron in the control of radiation-induced emesis.
Topics: Antiemetics; Humans; Imidazoles; Ondansetron; Pilot Projects; Radiation Injuries; Randomized Control | 1989 |
3 other studies available for ondansetron and Injuries, Radiation
| Article | Year |
|---|---|
Ondansetron, dexamethasone and an NK1 antagonist block radiation sickness in mice.
Topics: Animals; Antiemetics; Dexamethasone; Drug Therapy, Combination; Male; Mice; Mice, Inbred ICR; Neurok | 2005 |
Ondansetron antiemetic therapy for chemotherapy and radiotherapy induced vomiting in children.
Topics: Child; Child, Preschool; Humans; Lymphoma, T-Cell; Nausea; Ondansetron; Precursor Cell Lymphoblastic | 1992 |
[New, in Austria registered specialty drugs. Zofran (Ondansetron, Glaxo)].
Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Austria; Dose-Response Relationsh | 1991 |