ondansetron has been researched along with Idiopathic Parkinson Disease in 11 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This systematic review identified published studies that evaluated the use of ondansetron in individuals with psychosis associated with dementia." | 8.98 | Is ondansetron beneficial for psychosis associated with dementia?. ( Farheen, SA; Lingamchetty, T; Maksimowski, M; Tampi, RR, 2018) |
| "This systematic review identified published studies that evaluated the use of ondansetron in individuals with psychosis associated with dementia." | 4.98 | Is ondansetron beneficial for psychosis associated with dementia?. ( Farheen, SA; Lingamchetty, T; Maksimowski, M; Tampi, RR, 2018) |
| " In the prelevodopa era, depression and other psychiatric disorders were described in PD, but in untreated patients psychosis was rare." | 4.79 | Parkinson's disease: drug-induced psychiatric states. ( Brown, D; Factor, SA; Molho, ES; Podskalny, GD, 1995) |
| "Ondansetron did not cause any worsening in basic PD symptoms or levodopa efficacy and was well tolerated with no major side effects." | 2.68 | Psychosis in advanced Parkinson's disease: treatment with ondansetron, a 5-HT3 receptor antagonist. ( Friedberg, G; Livneh, M; Melamed, E; Zoldan, J, 1995) |
| "Psychotic symptoms in Parkinson's disease (PD) are relatively common and, in addition to creating a disturbance in patients' daily lives, have consistently been shown to be associated with poor outcome." | 2.44 | Pathophysiology and treatment of psychosis in Parkinson's disease: a review. ( Fernandez, HH; Zahodne, LB, 2008) |
| "We hypothesized that hyperalgesia of 6-OHDA rats may be related to increased excitability of SDH neurons, and functional change of 5-HT3 receptor may reverse the hyperalgesia of 6-OHDA lesioned rats and decrease cell excitability of SDH neurons." | 1.72 | Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson's Disease. ( An, MQ; Dai, YP; Dong, LG; Gu, HY; Li, CJ; Liu, CF; Liu, LB; Mao, CJ; Wang, F; Zhang, LG, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Li, CJ | 1 |
| Zhang, LG | 1 |
| Liu, LB | 1 |
| An, MQ | 1 |
| Dong, LG | 1 |
| Gu, HY | 1 |
| Dai, YP | 1 |
| Wang, F | 1 |
| Mao, CJ | 1 |
| Liu, CF | 1 |
| Kwan, C | 1 |
| Huot, P | 1 |
| Schoen, NB | 1 |
| Jermakowicz, WJ | 1 |
| Luca, CC | 1 |
| Jagid, JR | 1 |
| Tampi, RR | 1 |
| Maksimowski, M | 1 |
| Lingamchetty, T | 1 |
| Farheen, SA | 1 |
| Simonetto, M | 1 |
| Ferigo, L | 1 |
| Zanet, L | 1 |
| Capus, L | 1 |
| Antonutti, L | 1 |
| Zorzon, M | 1 |
| Pizzolato, G | 1 |
| Zahodne, LB | 1 |
| Fernandez, HH | 1 |
| Rasimas, JJ | 1 |
| Zoldan, J | 3 |
| Friedberg, G | 3 |
| Livneh, M | 1 |
| Melamed, E | 3 |
| Factor, SA | 1 |
| Molho, ES | 1 |
| Podskalny, GD | 1 |
| Brown, D | 1 |
| Goldberg-Stern, H | 1 |
| Weizman, A | 1 |
3 reviews available for ondansetron and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Is ondansetron beneficial for psychosis associated with dementia?.
Topics: Antipsychotic Agents; Cognition Disorders; Dementia; Humans; Ondansetron; Parkinson Disease; Psychot | 2018 |
Pathophysiology and treatment of psychosis in Parkinson's disease: a review.
Topics: Antidepressive Agents; Antipsychotic Agents; Cholinesterase Inhibitors; Clinical Trials as Topic; El | 2008 |
Parkinson's disease: drug-induced psychiatric states.
Topics: Aged; Anxiety; Bipolar Disorder; Clozapine; Depression; Electroconvulsive Therapy; Humans; Levodopa; | 1995 |
3 trials available for ondansetron and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Psychosis in advanced Parkinson's disease: treatment with ondansetron, a 5-HT3 receptor antagonist.
Topics: Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Ondansetron; Parkinson Disease; Psychose | 1995 |
Ondansetron for hallucinosis in advanced Parkinson's disease.
Topics: Aged; Female; Hallucinations; Humans; Male; Middle Aged; Ondansetron; Parkinson Disease | 1993 |
Ondansetron, a 5-HT3 antagonist for visual hallucinations and paranoid delusional disorder associated with chronic L-DOPA therapy in advanced Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Delusions; Female; Hallucinations; Humans; Levodopa; | 1996 |
5 other studies available for ondansetron and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson's Disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Hyperalgesia; Ondansetron; Oxidopamine; P | 2022 |
5-HT
Topics: Antipsychotic Agents; Humans; Ondansetron; Parkinson Disease; Psychotic Disorders; Receptors, Seroto | 2019 |
Acute symptomatic peri-lead edema 33 hours after deep brain stimulation surgery: a case report.
Topics: Anti-Inflammatory Agents; Brain Edema; Deep Brain Stimulation; Dexamethasone; Headache; Humans; Male | 2017 |
Acute Akinesia, an unusual complication in Parkinson's Disease: a case report.
Topics: Acute Disease; Aged; Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Creatine Kinase; Dis | 2008 |
Treatment of psychosis in Lewy body disease.
Topics: Comorbidity; Electroconvulsive Therapy; Humans; Lewy Body Disease; Ondansetron; Parkinson Disease; P | 2008 |