ondansetron has been researched along with Hypothermia in 5 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute doses of saline, nicotine, and varenicline were given to mice, and locomotor depression and hypothermia were measured." | 3.78 | Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo. ( Grady, SR; Marks, MJ; O'Neill, HC; Ortiz, NC, 2012) |
| "Pretreatment with ondansetron, a serotonin 5-HT3 receptor antagonist, which is used to treat nausea in patients in chemo- or radiation therapy, attenuated hypothermia by ~30%." | 1.40 | Thermoregulatory correlates of nausea in rats and musk shrews. ( Cerri, M; Corrigan, JJ; Del Vecchio, F; Dragic, AS; Kamphee, A; Nalivaiko, E; Ngampramuan, S; Romanovsky, AA; Rudd, JA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nnacheta, TE | 1 |
| Onyekwulu, FA | 1 |
| Amucheazi, AO | 1 |
| Ngampramuan, S | 1 |
| Cerri, M | 1 |
| Del Vecchio, F | 1 |
| Corrigan, JJ | 1 |
| Kamphee, A | 1 |
| Dragic, AS | 1 |
| Rudd, JA | 1 |
| Romanovsky, AA | 1 |
| Nalivaiko, E | 1 |
| Naumenko, VS | 1 |
| Kondaurova, EM | 1 |
| Popova, NK | 1 |
| Ortiz, NC | 1 |
| O'Neill, HC | 1 |
| Marks, MJ | 1 |
| Grady, SR | 1 |
| Alfonsi, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section. A Prospective, Observational and Non-inferiority Study Against Epidural Analgesia.[NCT05879536] | 312 participants (Anticipated) | Observational | 2023-05-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ondansetron and Hypothermia
| Article | Year |
|---|---|
Postanaesthetic shivering: epidemiology, pathophysiology, and approaches to prevention and management.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Hot Te | 2001 |
1 trial available for ondansetron and Hypothermia
| Article | Year |
|---|---|
Prevention of postanesthetic shivering under subarachnoid block for cesarean section: A randomized, controlled study comparing tramadol versus ondansetron.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Double-Bli | 2020 |
3 other studies available for ondansetron and Hypothermia
| Article | Year |
|---|---|
Thermoregulatory correlates of nausea in rats and musk shrews.
Topics: Animals; Body Temperature Regulation; Feeding Behavior; Hypothermia; Male; Motion Sickness; Nausea; | 2014 |
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Biguanides; Blood-Brain Barrier; Bo | 2009 |
Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo.
Topics: Animals; Benzazepines; Dose-Response Relationship, Drug; Female; Genotype; Hexamethonium; Hypothermi | 2012 |