Page last updated: 2024-11-01

ondansetron and Hypotension

ondansetron has been researched along with Hypotension in 28 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
" Our results manifested that intravenous ondansetron compared with intravenous placebo significantly reduced the incidence of post-anesthesia shivering (PAS) (RR 0."9.41A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section. ( Cao, F; Chen, C; Liu, J; Zhang, J; Zhang, L; Zheng, G, 2023)
" A prophylactic phenylephrine infusion was used to prevent hypotension."9.34A Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery. ( Chang, X; Chen, X; Ngan Kee, WD; Shen, H; Wei, C; Xiao, F; Xue, L; Zhang, Y, 2020)
"There was controversy about ondansetron can reduce the incidence of spinal-induced hypotension and decrease the consumption of vasopressor in cesarean delivery with spinal anesthesia."9.34Does an Earlier or Late Intravenous Injection of Ondansetron Affect the Dose of Phenylephrine Needed to Prevent Spinal-Anesthesia Induced Hypotension in Cesarean Sections? ( Liu, L; Qian, J; Xiao, F; Zheng, X, 2020)
"The weight-based dosing of ondansetron to reduce hypotension has never been investigated."9.27Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial. ( Dilokrattanaphijit, N; Karnjanawanichkul, O; Kunapaisal, T; Leeratiwong, J; Oofuvong, M, 2018)
"To evaluate the effect of prophylactic ondansetron on spinal anesthesia-induced hypotension and bradycardia among patients undergoing elective cesarean deliveries."9.22Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt. ( El Khouly, NI; Meligy, AM, 2016)
"Maternal hypotension and nausea were significantly lower in ondansetron-treated patients versus placebo (p = 0."9.19Ondansetron preloading with crystalloid infusion reduces maternal hypotension during cesarean delivery. ( Shen, MK; Wang, M; Wang, Q; Yu, JJ; Yu, YY; Zhuo, L, 2014)
"Ondansetron 4 mg, given intravenously 5 min before subarachnoid block reduced hypotension and vasopressor use in parturients undergoing elective caesarean section."9.16Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study. ( Goswami, A; Hazra, A; Sahoo, T; SenDasgupta, C, 2012)
" Prophylactic ondansetron reduced the incidence of spinal anesthesia-induced hypotension in both obstetric and non-obstetric patients."8.91Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis. ( Gao, L; Han, J; Wang, Y; Zheng, G; Zheng, J, 2015)
"Ondansetron is a 5-HT3 receptor antagonist which is generally used for the prophylactic management of nausea and vomiting; however, studies have found that ondansetron might decrease the incidence of PDPH."6.80Effect of ondansetron on post-dural puncture headache (PDPH) in parturients undergoing cesarean section: a double-blind randomized placebo-controlled study. ( Fattahi, Z; Hadavi, SM; Sahmeddini, MA, 2015)
"Metoclopramide was ineffective."6.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)
"This study showed the effectiveness of the prescription of 5 mg ephedrine two minutes before changing from the lithotomy position to the supine in maintaining hemodynamic stability, reducing hypotension, bradycardia, nausea, and vomiting, and the amount of prescribed ephedrine, atropine, and ondansetron."5.69The Prophylaxis Effect of Ephedrine on Hemodynamic Variation in Patients Undergoing Percutaneous Nephrolithotomy Surgery with Spinal Anesthesia. ( Bahrami, A; Darvishzadehdaledari, S; Golabi, P; Hamoud Alshahrani, S; Kamalov, Z; Kazemi Haki, B; Nasiri, AA; Sajid Abdulabbas, H; Sane, S, 2023)
"Maternal hypotension is common after spinal anesthesia for cesarean delivery."5.43Ephedrine versus ondansetron in the prevention of hypotension during cesarean delivery: a randomized, double-blind, placebo-controlled trial. ( Nivatpumin, P; Thamvittayakul, V, 2016)
" Our results manifested that intravenous ondansetron compared with intravenous placebo significantly reduced the incidence of post-anesthesia shivering (PAS) (RR 0."5.41A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section. ( Cao, F; Chen, C; Liu, J; Zhang, J; Zhang, L; Zheng, G, 2023)
" A prophylactic phenylephrine infusion was used to prevent hypotension."5.34A Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery. ( Chang, X; Chen, X; Ngan Kee, WD; Shen, H; Wei, C; Xiao, F; Xue, L; Zhang, Y, 2020)
"There was controversy about ondansetron can reduce the incidence of spinal-induced hypotension and decrease the consumption of vasopressor in cesarean delivery with spinal anesthesia."5.34Does an Earlier or Late Intravenous Injection of Ondansetron Affect the Dose of Phenylephrine Needed to Prevent Spinal-Anesthesia Induced Hypotension in Cesarean Sections? ( Liu, L; Qian, J; Xiao, F; Zheng, X, 2020)
"Eight milligrams of intravenous ondansetron given 5 min before spinal anesthesia attenuated but did not prevent spinal anesthesia-induced hypotension in parturients undergoing elective cesarean delivery."5.27Does prophylactic ondansetron reduce norepinephrine consumption in patients undergoing cesarean section with spinal anesthesia? ( Biricik, E; Büyükkurt, S; Karacaer, F; Ünal, İ; Ünlügenç, H, 2018)
"The weight-based dosing of ondansetron to reduce hypotension has never been investigated."5.27Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial. ( Dilokrattanaphijit, N; Karnjanawanichkul, O; Kunapaisal, T; Leeratiwong, J; Oofuvong, M, 2018)
"To evaluate the effect of prophylactic ondansetron on spinal anesthesia-induced hypotension and bradycardia among patients undergoing elective cesarean deliveries."5.22Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt. ( El Khouly, NI; Meligy, AM, 2016)
"Ondansetron was effectively used to prevent spinal anesthesia-induced hypotension in the general population and women anesthetised for cesarean section."5.20Ondansetron attenuates the decrease in blood pressure due to spinal anesthesia in the elderly: a double blind, placebo-controlled study. ( Dylczyk-Sommer, A; Jasiński, T; Marciniak, A; Owczuk, R; Polak-Krzemińska, A; Sawicka, W; Twardowski, P; Wenski, W; Wujtewicz, M; Wujtewicz, MA, 2015)
"verification of a hypothesis assuming that 5-HT3 receptor blockade by intravenous administration of ondansetron reduces the incidence of hypotension and bradycardia in patients undergoing spinal anaesthesia for Caesarean section."5.20The influence of intravenous ondansetron on maternal blood haemodynamics after spinal anaesthesia for caesarean section: a double-blind, placebo-controlled study. ( Majdyło, K; Marciniak, A; Owczuk, R; Preis, K; Wujtewicz, M, 2015)
"Maternal hypotension and nausea were significantly lower in ondansetron-treated patients versus placebo (p = 0."5.19Ondansetron preloading with crystalloid infusion reduces maternal hypotension during cesarean delivery. ( Shen, MK; Wang, M; Wang, Q; Yu, JJ; Yu, YY; Zhuo, L, 2014)
"Ondansetron 4 mg, given intravenously 5 min before subarachnoid block reduced hypotension and vasopressor use in parturients undergoing elective caesarean section."5.16Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study. ( Goswami, A; Hazra, A; Sahoo, T; SenDasgupta, C, 2012)
"While interventions such as crystalloids, colloids, ephedrine, phenylephrine, ondansetron, or lower leg compression can reduce the incidence of hypotension, none have been shown to eliminate the need to treat maternal hypotension in some women."5.05Techniques for preventing hypotension during spinal anaesthesia for caesarean section. ( Chemali, M; Chooi, C; Cox, JJ; Cyna, AM; Emmett, RS; Lumb, RS; Middleton, P; Simmons, SW, 2020)
" Prophylactic ondansetron reduced the incidence of spinal anesthesia-induced hypotension in both obstetric and non-obstetric patients."4.91Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis. ( Gao, L; Han, J; Wang, Y; Zheng, G; Zheng, J, 2015)
"Ondansetron is a 5-HT3 receptor antagonist which is generally used for the prophylactic management of nausea and vomiting; however, studies have found that ondansetron might decrease the incidence of PDPH."2.80Effect of ondansetron on post-dural puncture headache (PDPH) in parturients undergoing cesarean section: a double-blind randomized placebo-controlled study. ( Fattahi, Z; Hadavi, SM; Sahmeddini, MA, 2015)
"Metoclopramide was ineffective."2.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)
"Ondansetron has been proved to be valid in preventing postanaesthesia shivering (PAS) in several studies."2.53Efficiency and safety of ondansetron in preventing postanaesthesia shivering. ( He, K; Zhao, H; Zhou, HC, 2016)
"Maternal hypotension is common after spinal anesthesia for cesarean delivery."1.43Ephedrine versus ondansetron in the prevention of hypotension during cesarean delivery: a randomized, double-blind, placebo-controlled trial. ( Nivatpumin, P; Thamvittayakul, V, 2016)
"pretreatment with capsazepine, ondansetron or HC030031."1.40Linalool-rich rosewood oil induces vago-vagal bradycardic and depressor reflex in rats. ( Correia Junior, CA; da Cunha, PJ; da Silva, MT; de Siqueira, RJ; dos Santos, AA; Duarte, GP; Lahlou, S; Magalhães, PJ; Maia, JG; Rodrigues, KM, 2014)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's1 (3.57)29.6817
2010's19 (67.86)24.3611
2020's6 (21.43)2.80

Authors

AuthorsStudies
Zheng, G2
Zhang, J1
Liu, J1
Chen, C1
Zhang, L1
Cao, F1
Sane, S1
Nasiri, AA1
Bahrami, A1
Kamalov, Z1
Hamoud Alshahrani, S1
Sajid Abdulabbas, H1
Darvishzadehdaledari, S1
Golabi, P1
Kazemi Haki, B1
Xiao, F2
Wei, C1
Chang, X1
Zhang, Y1
Xue, L1
Shen, H1
Ngan Kee, WD1
Chen, X1
Chooi, C1
Cox, JJ1
Lumb, RS1
Middleton, P1
Chemali, M1
Emmett, RS1
Simmons, SW1
Cyna, AM1
Qian, J1
Liu, L1
Zheng, X1
D Tubog, T1
S Bramble, R1
Karacaer, F1
Biricik, E1
Ünal, İ1
Büyükkurt, S1
Ünlügenç, H1
Oofuvong, M1
Kunapaisal, T1
Karnjanawanichkul, O1
Dilokrattanaphijit, N1
Leeratiwong, J1
Tubog, TD1
Kane, TD1
Pugh, MA1
Barnhart, ML1
Rosenbaum, K1
de Siqueira, RJ2
Rodrigues, KM1
da Silva, MT1
Correia Junior, CA1
Duarte, GP2
Magalhães, PJ2
dos Santos, AA1
Maia, JG2
da Cunha, PJ1
Lahlou, S2
Wang, Q1
Zhuo, L1
Shen, MK1
Yu, YY1
Yu, JJ1
Wang, M1
Owczuk, R2
Wenski, W1
Twardowski, P1
Dylczyk-Sommer, A1
Sawicka, W1
Wujtewicz, MA1
Marciniak, A2
Polak-Krzemińska, A1
Jasiński, T1
Wujtewicz, M2
Merli, GJ1
Weitz, HH1
Fattahi, Z1
Hadavi, SM1
Sahmeddini, MA1
Preis, K1
Majdyło, K1
Gao, L1
Han, J1
Wang, Y1
Zheng, J1
Nivatpumin, P1
Thamvittayakul, V1
He, K1
Zhao, H1
Zhou, HC1
El Khouly, NI1
Meligy, AM1
Fernando, SL1
Broadfoot, AJ1
Macedo, FI1
Interaminense, Lde F1
Brito, TS1
da Silva, JK1
Sousa, PJ1
Leal-Cardoso, JH1
Fregoneze, JB1
Oliveira, EF1
Ribeiro, VF1
Ferreira, HS1
De Castro E Silva, E1
Sahoo, T1
SenDasgupta, C1
Goswami, A1
Hazra, A1
Ghafouri, N1
Darracq, MA1
Cantrell, FL1
Downs, AJ1
Poonawala, Y1
Desilva, PH1
Darvish, AH1
McDonald, SM1
Cronin, MK1
Clark, K1
Deshpande, SB1
Bagchi, S1
Rai, OP1
Aryya, NC1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A PROSPECTIVE, RANDOMIZED, DOUBLE-BLINDED STUDY OF THE EFFECT OF A STANDARD DOSE OF INTRAVENOUS ONDANSETRON ON THE EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAR[NCT04703088]Phase 360 participants (Anticipated)Interventional2021-06-30Not yet recruiting
Evaluation of the Efficacy of 6% Hydroxyethyl Starch (HES, 130/0.4) in Normal Saline Compared to Ringer's Lactate Solution for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section[NCT00694343]Phase 4167 participants (Actual)Interventional2008-06-30Completed
The Time Required to Remain Sitting After Spinal Anesthesia for 50% of Patients to Not Experience Hypotension[NCT01561274]Phase 250 participants (Actual)Interventional2012-03-31Completed
The Oxygenation of the Brain During Caesarean Section. A Comparison of Ephedrine Versus Phenylephrine[NCT01509521]Phase 424 participants (Anticipated)Interventional2012-02-29Completed
Electrical Acupoint Stimulation Alleviates Hypotension After Spinal Anesthesia in Parturients: a Prospective Randomized Controlled Clinical Trial[NCT05724095]90 participants (Actual)Interventional2023-02-20Completed
Does Prophylactic Ondansetron Reduce Norepinephrine Consumption in Patients Undergoing Caesarean Section With Spinal Anesthesia?[NCT02928601]Phase 4108 participants (Actual)Interventional2016-11-30Completed
The Efficacy of Neostigmine as an Adjuvant to Bupivacaine for Intrathecal Block in Reducing the Incidence and Severity of Post-Dural Puncture Headache for Parturients Scheduled for Elective Caesarean Section[NCT03587441]Phase 4240 participants (Actual)Interventional2018-08-04Completed
The Efficacy and Safety of Ramosetron in Patients Undergoing Off Pump Coronary Artery Bypass Surgery[NCT02139241]114 participants (Actual)Interventional2013-06-30Completed
Prophylaxis Ephedrine or Ondansetron Prevents Hypotension After Spinal Anesthesia for Cesarean Section; a Randomized, Double Blinded, Placebo Controlled Trial[NCT02194192]168 participants (Actual)Interventional2014-07-31Completed
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non-elective Caesarean Section: A Prospective Observational Study[NCT04692870]337 participants (Actual)Observational2021-01-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for ondansetron and Hypotension

ArticleYear
A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section.
    Archives of gynecology and obstetrics, 2023, Volume: 307, Issue:1

    Topics: Anesthesia; Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Female; Humans; Hypotension;

2023
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
    The Cochrane database of systematic reviews, 2020, 07-01, Volume: 7

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Colloids; Crystalloid So

2020
Ondansetron reduces the incidence of hypotension after spinal anaesthesia in non-caesarean delivery: A systematic review and meta-analysis.
    Journal of perioperative practice, 2022, Volume: 32, Issue:3

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Ephedrine; Humans; Hypotension; Incidence;

2022
Effects of Ondansetron on Attenuating Spinal Anesthesia–Induced Hypotension and Bradycardia in Obstetric and Nonobstetric Subjects: A Systematic Review and Meta-Analysis.
    AANA journal, 2017, Volume: 85, Issue:2

    Topics: Anesthesia, Spinal; Antiemetics; Bradycardia; Delivery, Obstetric; Female; Humans; Hypotension; Infu

2017
Web Exclusives. The consult guys - twisted after surgery: what caused torsades?
    Annals of internal medicine, 2015, 02-17, Volume: 162, Issue:4

    Topics: Antiemetics; Craniotomy; Electrocardiography; Female; Humans; Hypotension; Intracranial Aneurysm; Mi

2015
Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Anesthesia, Spinal; Humans; Hypotension; Ondansetron; Serotonin Antagonists

2015
Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Anesthesia, Spinal; Humans; Hypotension; Ondansetron; Serotonin Antagonists

2015
Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Anesthesia, Spinal; Humans; Hypotension; Ondansetron; Serotonin Antagonists

2015
Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Anesthesia, Spinal; Humans; Hypotension; Ondansetron; Serotonin Antagonists

2015
Efficiency and safety of ondansetron in preventing postanaesthesia shivering.
    Annals of the Royal College of Surgeons of England, 2016, Volume: 98, Issue:6

    Topics: Anesthesia Recovery Period; Humans; Hypotension; Ondansetron; Postoperative Complications; Randomize

2016

Trials

12 trials available for ondansetron and Hypotension

ArticleYear
The Prophylaxis Effect of Ephedrine on Hemodynamic Variation in Patients Undergoing Percutaneous Nephrolithotomy Surgery with Spinal Anesthesia.
    International journal of clinical practice, 2023, Volume: 2023

    Topics: Anesthesia, Spinal; Atropine; Bradycardia; Ephedrine; Hemodynamics; Humans; Hypotension; Nausea; Nep

2023
A Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:2

    Topics: Adult; Anesthesia, Spinal; Antiemetics; Cesarean Section; Dose-Response Relationship, Drug; Double-B

2020
Does an Earlier or Late Intravenous Injection of Ondansetron Affect the Dose of Phenylephrine Needed to Prevent Spinal-Anesthesia Induced Hypotension in Cesarean Sections?
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Adult; Anesthesia, Spinal; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method;

2020
Does prophylactic ondansetron reduce norepinephrine consumption in patients undergoing cesarean section with spinal anesthesia?
    Journal of anesthesia, 2018, Volume: 32, Issue:1

    Topics: Administration, Intravenous; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cardiac Output; Ces

2018
Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial.
    BMC anesthesiology, 2018, 08-15, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Adult; Anesthesia, Spinal; Blood Loss, Surgical; Blood Pressure; Blood

2018
Ondansetron preloading with crystalloid infusion reduces maternal hypotension during cesarean delivery.
    American journal of perinatology, 2014, Volume: 31, Issue:10

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Anxiety Agents; Blood Pressure; Carbon Diox

2014
Ondansetron attenuates the decrease in blood pressure due to spinal anesthesia in the elderly: a double blind, placebo-controlled study.
    Minerva anestesiologica, 2015, Volume: 81, Issue:6

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Antiemetics; Blood Pressure; Double-Blind Method; Femal

2015
Effect of ondansetron on post-dural puncture headache (PDPH) in parturients undergoing cesarean section: a double-blind randomized placebo-controlled study.
    Journal of anesthesia, 2015, Volume: 29, Issue:5

    Topics: Adult; Anesthesia, Spinal; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Hypot

2015
The influence of intravenous ondansetron on maternal blood haemodynamics after spinal anaesthesia for caesarean section: a double-blind, placebo-controlled study.
    Ginekologia polska, 2015, Volume: 86, Issue:6

    Topics: Antiemetics; Blood Pressure; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method

2015
Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 135, Issue:2

    Topics: Administration, Intravenous; Adult; Anesthesia, Spinal; Blood Pressure; Bradycardia; Cesarean Sectio

2016
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind M

2012
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension

1995

Other Studies

9 other studies available for ondansetron and Hypotension

ArticleYear
Anaphylactoid Syndrome of Pregnancy.
    Nursing for women's health, 2019, Volume: 23, Issue:1

    Topics: Adult; Antipruritics; Atropine; Cyclooxygenase Inhibitors; Female; Humans; Hypotension; IgA Vasculit

2019
Linalool-rich rosewood oil induces vago-vagal bradycardic and depressor reflex in rats.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:1

    Topics: Acetanilides; Acyclic Monoterpenes; Animals; Aorta; Atropine Derivatives; Blood Pressure; Bradycardi

2014
Ephedrine versus ondansetron in the prevention of hypotension during cesarean delivery: a randomized, double-blind, placebo-controlled trial.
    International journal of obstetric anesthesia, 2016, Volume: 27

    Topics: Adult; Blood Pressure; Cesarean Section; Double-Blind Method; Ephedrine; Female; Humans; Hypotension

2016
Ondansetron anaphylaxis: a case report and protocol for skin testing.
    British journal of anaesthesia, 2009, Volume: 102, Issue:2

    Topics: Adult; Anaphylaxis; Antiemetics; Female; Humans; Hypotension; Intraoperative Complications; Ondanset

2009
1-Nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, elicits a vago-vagal bradycardiac and depressor reflex in normotensive rats.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Animals; Aorta; Atropine Derivatives; Benzene Derivatives; Bradycardia; Capsaicin; Cryptocarya; Dose

2010
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
    Neuropeptides, 2011, Volume: 45, Issue:3

    Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic A

2011
Ondansetron-associated hypotension following pediatric self-poisoning.
    Pediatric emergency care, 2012, Volume: 28, Issue:6

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Drug Overdose; Emergencies; Huma

2012
Reduction in spinal-induced hypotension with ondansetron.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:4

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Female; Humans; Hypotension; Ondansetron; Pregnancy; Se

2012
Pulmonary oedema produced by scorpion venom augments a phenyldiguanide-induced reflex response in anaesthetized rats.
    The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2

    Topics: Anesthetics, Intravenous; Animals; Apnea; Aprotinin; Biguanides; Bradycardia; Drug Synergism; Female

1999