Page last updated: 2024-11-01

ondansetron and Heart Failure

ondansetron has been researched along with Heart Failure in 2 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Optical mapping was performed in rabbit hearts with pacing-induced heart failure (HF) and in normal hearts before and after ondansetron (100 nM) infusion."3.96Effects of ondansetron on apamin-sensitive small conductance calcium-activated potassium currents in pacing-induced failing rabbit hearts. ( Chen, M; Chen, PS; Chen, Z; Everett, TH; Kamp, NJ; Lin, SF; Rubart-von der Lohe, M; Shen, C; Tian, Z; Wang, Z; Wu, AZ; Xu, D; Yang, N; Yin, D, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Yin, D1
Yang, N1
Tian, Z1
Wu, AZ1
Xu, D1
Chen, M1
Kamp, NJ1
Wang, Z1
Shen, C1
Chen, Z1
Lin, SF1
Rubart-von der Lohe, M1
Chen, PS1
Everett, TH1
Keefe, DL1

Reviews

1 review available for ondansetron and Heart Failure

ArticleYear
The cardiotoxic potential of the 5-HT(3) receptor antagonist antiemetics: is there cause for concern?
    The oncologist, 2002, Volume: 7, Issue:1

    Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Drug Interactions; Electrocardiog

2002

Other Studies

1 other study available for ondansetron and Heart Failure

ArticleYear
Effects of ondansetron on apamin-sensitive small conductance calcium-activated potassium currents in pacing-induced failing rabbit hearts.
    Heart rhythm, 2020, Volume: 17, Issue:2

    Topics: Action Potentials; Animals; Apamin; Cardiac Pacing, Artificial; Disease Models, Animal; Heart Failur

2020