Page last updated: 2024-11-01

ondansetron and Harelip

ondansetron has been researched along with Harelip in 7 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy."9.05Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis. ( Berard, A; Cottin, J; Cucherat, M; Grenet, G; Picot, C; Ripoche, E, 2020)
"Although there is no recommendation in France relating to the treatment of nausea and vomiting of pregnancy, there are some in other countries, where ondansetron, widely used, appears to be an effective second-line treatment option behind doxylamine/vitamin B6 association and metoclopramide."8.02[Nausea and vomiting in pregnancy: A place for ondansetron?] ( Coulm, B, 2021)
"Ondansetron is an effective antiemetic that is being widely used as a second-line treatment option for severe nausea and vomiting of pregnancy in accordance with clinical guidelines."8.02Ondansetron in pregnancy revisited: Assessment and pregnancy labelling by the European Medicines Agency (EMA) & Pharmacovigilance Risk Assessment Committee (PRAC). ( Cassina, M; Damkier, P; Diav-Citrin, O; Kaplan, YC; Shechtman, S; Weber-Schoendorfer, C, 2021)
"Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy."5.05Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis. ( Berard, A; Cottin, J; Cucherat, M; Grenet, G; Picot, C; Ripoche, E, 2020)
"Although there is no recommendation in France relating to the treatment of nausea and vomiting of pregnancy, there are some in other countries, where ondansetron, widely used, appears to be an effective second-line treatment option behind doxylamine/vitamin B6 association and metoclopramide."4.02[Nausea and vomiting in pregnancy: A place for ondansetron?] ( Coulm, B, 2021)
"Ondansetron is an effective antiemetic that is being widely used as a second-line treatment option for severe nausea and vomiting of pregnancy in accordance with clinical guidelines."4.02Ondansetron in pregnancy revisited: Assessment and pregnancy labelling by the European Medicines Agency (EMA) & Pharmacovigilance Risk Assessment Committee (PRAC). ( Cassina, M; Damkier, P; Diav-Citrin, O; Kaplan, YC; Shechtman, S; Weber-Schoendorfer, C, 2021)
"Evidence for the fetal safety of ondansetron, a 5-HT3 receptor antagonist that is commonly prescribed for nausea and vomiting during pregnancy, is limited and conflicting."3.88Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring. ( Bateman, BT; Desai, RJ; Gray, KJ; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Patorno, E; Straub, L; Zhu, Y, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Coulm, B1
Huybrechts, KF2
Hernandez-Diaz, S3
Straub, L2
Gray, KJ2
Zhu, Y2
Mogun, H2
Bateman, BT2
Picot, C1
Berard, A1
Grenet, G1
Ripoche, E1
Cucherat, M1
Cottin, J1
Damkier, P1
Kaplan, YC1
Shechtman, S1
Diav-Citrin, O1
Cassina, M1
Weber-Schoendorfer, C1
Patorno, E1
Desai, RJ1
Míguez Fortes, L1
Lema Carril, A1
Gómez Tellado, M1
Casal Beloy, I1
Blanco Portals, C1
García González, M1
Rodríguez Ruiz, M1
Somoza Argibay, I1
Dargallo Carbonell, T1
Anderka, M1
Mitchell, AA1
Louik, C1
Werler, MM1
Rasmussen, SA1

Reviews

1 review available for ondansetron and Harelip

ArticleYear
Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis.
    Birth defects research, 2020, Volume: 112, Issue:13

    Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Female; Humans; Ondansetron; Preg

2020

Other Studies

6 other studies available for ondansetron and Harelip

ArticleYear
[Nausea and vomiting in pregnancy: A place for ondansetron?]
    Gynecologie, obstetrique, fertilite & senologie, 2021, Volume: 49, Issue:12

    Topics: Antiemetics; Cleft Lip; Cleft Palate; Female; Humans; Nausea; Ondansetron; Pregnancy; Vomiting

2021
Intravenous Ondansetron in Pregnancy and Risk of Congenital Malformations.
    JAMA, 2020, 01-28, Volume: 323, Issue:4

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Antiemetics; Cleft Lip; Cleft Palate; Fema

2020
Ondansetron in pregnancy revisited: Assessment and pregnancy labelling by the European Medicines Agency (EMA) & Pharmacovigilance Risk Assessment Committee (PRAC).
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:4

    Topics: Antiemetics; Cleft Lip; Cleft Palate; Contraindications, Drug; Drug Labeling; European Union; Female

2021
Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring.
    JAMA, 2018, 12-18, Volume: 320, Issue:23

    Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Cleft Lip; Cleft Palate; Female; Heart Defects, Con

2018
[Parent controled analgesia system in postoperative pain management in patients undergoing lip and cleft palate surgery].
    Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2019, Jan-21, Volume: 32, Issue:1

    Topics: Analgesia, Patient-Controlled; Child, Preschool; Cleft Lip; Cleft Palate; Dipyrone; Female; Humans;

2019
Medications used to treat nausea and vomiting of pregnancy and the risk of selected birth defects.
    Birth defects research. Part A, Clinical and molecular teratology, 2012, Volume: 94, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Humans; H

2012