Page last updated: 2024-11-01

ondansetron and Fibromyalgia

ondansetron has been researched along with Fibromyalgia in 2 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"To study the efficacy of 5-hydroxytryptamine type 3 receptor (5-HT-3R) antagonist (ondansetron) vs paracetamol in primary fibromyalgia (FM) syndrome."9.08Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study. ( Hrycaj, P; Mennet, P; Müller, W; Stratz, T, 1996)
"To study the efficacy of 5-hydroxytryptamine type 3 receptor (5-HT-3R) antagonist (ondansetron) vs paracetamol in primary fibromyalgia (FM) syndrome."5.08Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study. ( Hrycaj, P; Mennet, P; Müller, W; Stratz, T, 1996)
"After confirming hyperalgesia, male mice were treated with αTPN-βCD (25, 50 or 100 mg/kg; p."1.43α-Terpineol, a monoterpene alcohol, complexed with β-cyclodextrin exerts antihyperalgesic effect in animal model for fibromyalgia aided with docking study. ( Almeida, JR; Araújo, AA; Araújo-Filho, HG; Brito, RG; Carvalho, YM; Menezes, PP; Oliveira, MG; Quintans, JS; Quintans-Júnior, LJ; Santos, PL; Scotti, L; Scotti, MT; Serafini, MR; Shanmugam, S; Silva, JC; Thangaraj, P, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oliveira, MG1
Brito, RG1
Santos, PL1
Araújo-Filho, HG1
Quintans, JS1
Menezes, PP1
Serafini, MR1
Carvalho, YM1
Silva, JC1
Almeida, JR1
Scotti, L1
Scotti, MT1
Shanmugam, S1
Thangaraj, P1
Araújo, AA1
Quintans-Júnior, LJ1
Hrycaj, P1
Stratz, T1
Mennet, P1
Müller, W1

Trials

1 trial available for ondansetron and Fibromyalgia

ArticleYear
Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study.
    The Journal of rheumatology, 1996, Volume: 23, Issue:8

    Topics: Acetaminophen; Adult; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; Male; M

1996

Other Studies

1 other study available for ondansetron and Fibromyalgia

ArticleYear
α-Terpineol, a monoterpene alcohol, complexed with β-cyclodextrin exerts antihyperalgesic effect in animal model for fibromyalgia aided with docking study.
    Chemico-biological interactions, 2016, Jul-25, Volume: 254

    Topics: Analgesics; Animals; Behavior, Animal; beta-Cyclodextrins; Binding Sites; Cyclohexane Monoterpenes;

2016