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ondansetron and Female Genital Neoplasms

ondansetron has been researched along with Female Genital Neoplasms in 11 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Successful control of vomiting was achieved in the first 24 hours, in 74% of the cycles containing cisplatin and 82% of the cycles without cisplatin, if ondansetron was used."9.08Ondansetron in chemotherapy-induced emesis. Our experience. ( Bandiera, AF; Fiorelli, C; Framarino dei Malatesta, M; Marzetti, L; Toccaceli Blasi, MR; Veneziano, M; Yacoub, M, 1995)
"Twenty-nine patients with gynecologic malignancies were treated with a fixed low dose of intravenous ondansetron (8 mg) plus dexamethasone (20 mg) in an effort to develop an effective and less expensive antiemetic regimen for the control of carboplatin-induced emesis."9.08Low-dose intravenous ondansetron (8 mg) plus dexamethasone: an effective regimen for the control of carboplatin-induced emesis. ( Belinson, J; Kennedy, A; Kulp, B; Markman, M; Peterson, G; Webster, K, 1997)
"The inhibitory effects of GG032X tablets, a new dosage form (fast dispersing tablet) of ondansetron, 5-HT2 receptor antagonist, on nausea and emesis induced by cisplatin (CDDP), were investigated along with safety and usefulness."9.08[Clinical efficacy of GG032X tablets, a new dosage form of ondansetron (fast dispersing tablet), on cisplatin-induced nausea and emesis]. ( Akasaka, Y; Ariyoshi, Y; Ikeda, M; Nukariya, N; Ota, J; Suminaga, M; Taguchi, T, 1997)
"To compare the efficacy between acupuncture and ondansetron in the prevention of delayed chemotherapy induced nausea and vomiting (CINV)."5.20Efficacy of acupuncture in prevention of delayed chemotherapy induced nausea and vomiting in gynecologic cancer patients. ( Akkayagorn, L; Manchana, T; Rithirangsriroj, K, 2015)
"To evaluate the antiemetic effect of a single dose of ondansetron and dexamethasone as a prophylaxis for chemotherapy induced acute nausea and emesis and factors associated with the control of acute nausea and emesis."5.12Antiemetic effect of ondansetron and dexamethasone in gynecologic malignant patients receiving chemotherapy. ( Manusirivithaya, S; Pradermdee, P; Sukwattana, P; Tangjitgamol, S; Thavaramara, T, 2006)
"The efficacy of an intravenous 5-HT3 antagonist (granisetron) and four oral 5-HT3 antagonists (granisetron, ondansetron, tropisetron and ramosetron) on chemotherapy-induced emesis were investigated in 21 gynecologic cancer patients (63 courses)."5.09[Effects of oral 5-HT3 antagonists on chemotherapy-induced emesis in patients with gynecologic cancers]. ( Akutagawa, N; Ishioka, S; Ito, E; Kiya, T; Kudo, R; Sagae, S; Saito, T; Sugimura, M; Umemura, K, 2000)
"The purpose of this study was to develop a cost-effective prophylactic antiemetic regimen for the prevention of carboplatin-induced emesis."5.09The antiemetic efficacy of oral ondansetron plus intravenous dexamethasone in patients with gynecologic malignancies receiving carboplatin-based chemotherapy. ( Belinson, J; Kennedy, A; Kulp, B; Markman, M; Peterson, G; Webster, K, 2000)
"Successful control of vomiting was achieved in the first 24 hours, in 74% of the cycles containing cisplatin and 82% of the cycles without cisplatin, if ondansetron was used."5.08Ondansetron in chemotherapy-induced emesis. Our experience. ( Bandiera, AF; Fiorelli, C; Framarino dei Malatesta, M; Marzetti, L; Toccaceli Blasi, MR; Veneziano, M; Yacoub, M, 1995)
"Twenty-nine patients with gynecologic malignancies were treated with a fixed low dose of intravenous ondansetron (8 mg) plus dexamethasone (20 mg) in an effort to develop an effective and less expensive antiemetic regimen for the control of carboplatin-induced emesis."5.08Low-dose intravenous ondansetron (8 mg) plus dexamethasone: an effective regimen for the control of carboplatin-induced emesis. ( Belinson, J; Kennedy, A; Kulp, B; Markman, M; Peterson, G; Webster, K, 1997)
"The inhibitory effects of GG032X tablets, a new dosage form (fast dispersing tablet) of ondansetron, 5-HT2 receptor antagonist, on nausea and emesis induced by cisplatin (CDDP), were investigated along with safety and usefulness."5.08[Clinical efficacy of GG032X tablets, a new dosage form of ondansetron (fast dispersing tablet), on cisplatin-induced nausea and emesis]. ( Akasaka, Y; Ariyoshi, Y; Ikeda, M; Nukariya, N; Ota, J; Suminaga, M; Taguchi, T, 1997)
"In the large majority of patients, serotonin-receptor antagonist antiemetic therapy, administered in combination with dexamethasone, is highly effective over multiple courses in preventing significant carboplatin-induced nausea and vomiting."3.71Effectiveness of serotonin-receptor antagonist antiemetic therapy over successive courses of carboplatin-based chemotherapy. ( Kulp, B; Markman, M; Markman, MR; Peterson, G, 2002)
" Adverse reactions were observed in 2 cases (2 reports of headache) in the OND group and 5 cases (2 reports of hiccups, 2 headache, 2 diarrhea, one constipation, one hot facial flushes and one elevation of gamma-GTP) in the DEX group; however, since the symptoms were all mild, we did not consider there was any problem in safety."2.70[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in gynecological cancer patients on cisplatin]. ( Eguchi, F; Furue, H; Ikeda, M; Taguchi, T; Tsukakoshi, S, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's6 (54.55)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rithirangsriroj, K1
Manchana, T1
Akkayagorn, L1
Pradermdee, P1
Manusirivithaya, S1
Tangjitgamol, S1
Thavaramara, T1
Sukwattana, P1
Framarino dei Malatesta, M2
Veneziano, M2
Fiorelli, C2
Bandiera, AF2
Yacoub, M1
Toccaceli Blasi, MR1
Marzetti, L1
Galati, M1
Paolucci, A1
Markman, M3
Kennedy, A2
Webster, K2
Peterson, G3
Kulp, B3
Belinson, J2
Ariyoshi, Y1
Nukariya, N1
Akasaka, Y1
Suminaga, M1
Ota, J1
Ikeda, M2
Taguchi, T2
Ishioka, S1
Sagae, S1
Saito, T1
Kiya, T1
Sugimura, M1
Akutagawa, N1
Umemura, K1
Ito, E1
Kudo, R1
Eguchi, F1
Furue, H1
Tsukakoshi, S1
Markman, MR1
Lehoczky, O1
Udvary, J1
Pulay, T1

Trials

9 trials available for ondansetron and Female Genital Neoplasms

ArticleYear
Efficacy of acupuncture in prevention of delayed chemotherapy induced nausea and vomiting in gynecologic cancer patients.
    Gynecologic oncology, 2015, Volume: 136, Issue:1

    Topics: Acupuncture Therapy; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cross

2015
Antiemetic effect of ondansetron and dexamethasone in gynecologic malignant patients receiving chemotherapy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89 Suppl 4

    Topics: Acute Disease; Adult; Age Factors; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cis

2006
Ondansetron in chemotherapy-induced emesis. Our experience.
    European journal of gynaecological oncology, 1995, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Genital Neoplas

1995
Low-dose intravenous ondansetron (8 mg) plus dexamethasone: an effective regimen for the control of carboplatin-induced emesis.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Carboplatin; Dexamethasone; Drug

1997
[Clinical efficacy of GG032X tablets, a new dosage form of ondansetron (fast dispersing tablet), on cisplatin-induced nausea and emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Administratio

1997
[Effects of oral 5-HT3 antagonists on chemotherapy-induced emesis in patients with gynecologic cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4

    Topics: Administration, Oral; Antiemetics; Benzimidazoles; Carboplatin; Cisplatin; Cyclophosphamide; Doxorub

2000
The antiemetic efficacy of oral ondansetron plus intravenous dexamethasone in patients with gynecologic malignancies receiving carboplatin-based chemotherapy.
    Gynecologic oncology, 2000, Volume: 78, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Antineopla

2000
[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in gynecological cancer patients on cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:10

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Gen

2001
Freeze dried ondansetron: first observations with the fast dissolving oral antiemetic Zofran Zydis for the prophylaxis of the cisplatin-induced emesis in gynecological cancer patients.
    Neoplasma, 2002, Volume: 49, Issue:2

    Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Female; Freeze D

2002

Other Studies

2 other studies available for ondansetron and Female Genital Neoplasms

ArticleYear
Ondansetron-induced headache. Our experience in gynecological cancer.
    European journal of gynaecological oncology, 1995, Volume: 16, Issue:3

    Topics: Breast Neoplasms; Female; Genital Neoplasms, Female; Headache; Humans; Migraine Disorders; Ondansetr

1995
Effectiveness of serotonin-receptor antagonist antiemetic therapy over successive courses of carboplatin-based chemotherapy.
    Gynecologic oncology, 2002, Volume: 85, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bridged

2002