ondansetron has been researched along with Epilepsy, Tonic-Clonic in 3 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection." | 5.35 | Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009) |
| "A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection." | 1.35 | Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arens, A | 1 |
| Smollin, C | 1 |
| Singh, NN | 1 |
| Rai, A | 1 |
| Selhorst, JB | 1 |
| Acharya, JN | 1 |
| Mizoguchi, H | 1 |
| Suzuki, T | 1 |
| Misawa, M | 1 |
3 other studies available for ondansetron and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Case Files of the University of California, San Francisco Medical Toxicology Fellowship: Seizures and a Persistent Anion Gap Metabolic Acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; | 2016 |
Ondansetron and seizures.
Topics: Adult; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; | 2009 |
Effects of serotonergic anxiolytics on physical dependence on diazepam in mice.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Carbolines; Diazepam; Drug Synergism; Epilepsy, Tonic-Cloni | 1993 |