ondansetron has been researched along with Dysgerminoma in 2 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Dysgerminoma: A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients who had suffered severe vomiting on carboplatin alone (23 patients with ovarian carcinoma) or in combination (two patients with testicular cancer) despite intensive antiemetic regimens were treated with ondansetron, given as 8 mg immediately prior to carboplatin followed by 8 mg orally, 8 hourly for 5 days." | 9.07 | Reduction of carboplatin induced emesis by ondansetron. ( Dickson, DS; Evans, BD; Harvey, VJ; Langley, GB; Mak, D; Mitchell, PL; Neave, LM, 1991) |
| " Patients who had suffered severe vomiting on carboplatin alone (23 patients with ovarian carcinoma) or in combination (two patients with testicular cancer) despite intensive antiemetic regimens were treated with ondansetron, given as 8 mg immediately prior to carboplatin followed by 8 mg orally, 8 hourly for 5 days." | 5.07 | Reduction of carboplatin induced emesis by ondansetron. ( Dickson, DS; Evans, BD; Harvey, VJ; Langley, GB; Mak, D; Mitchell, PL; Neave, LM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tong, D | 1 |
| Harvey, VJ | 1 |
| Evans, BD | 1 |
| Mitchell, PL | 1 |
| Mak, D | 1 |
| Neave, LM | 1 |
| Langley, GB | 1 |
| Dickson, DS | 1 |
1 trial available for ondansetron and Dysgerminoma
| Article | Year |
|---|---|
Reduction of carboplatin induced emesis by ondansetron.
Topics: Antiemetics; Carboplatin; Dysgerminoma; Female; Humans; Imidazoles; Male; Middle Aged; Nausea; Ondan | 1991 |
1 other study available for ondansetron and Dysgerminoma
| Article | Year |
|---|---|
Ondansetron and radiotherapy.
Topics: Adult; Antiemetics; Dysgerminoma; Humans; Imidazoles; Male; Middle Aged; Ondansetron; Radiotherapy; | 1992 |