ondansetron has been researched along with Depressive Disorder in 11 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present work was to investigate the role of ondansetron on the high fat diet (HFD) induced obese mice for behavioral and biochemical alterations using chronic unpredictable mild stress (CUMS) model of depression." | 7.80 | Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2014) |
| " Therefore, the present study was aimed at investigating the effect of ondansetron, a selective 5HT3 receptor antagonist in attenuating depression and anxiety-like behavior comorbid with diabetes." | 7.80 | Ondansetron, a 5HT3 receptor antagonist reverses depression and anxiety-like behavior in streptozotocin-induced diabetic mice: possible implication of serotonergic system. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2014) |
| "The aim of the present work was to investigate the role of ondansetron on the high fat diet (HFD) induced obese mice for behavioral and biochemical alterations using chronic unpredictable mild stress (CUMS) model of depression." | 3.80 | Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2014) |
| " Therefore, the present study was aimed at investigating the effect of ondansetron, a selective 5HT3 receptor antagonist in attenuating depression and anxiety-like behavior comorbid with diabetes." | 3.80 | Ondansetron, a 5HT3 receptor antagonist reverses depression and anxiety-like behavior in streptozotocin-induced diabetic mice: possible implication of serotonergic system. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2014) |
| "A 41-year-old woman with a strong history of postoperative nausea and vomiting presented for abdominal hysterectomy 3 months after a previous anaesthetic where ondansetron prophylaxis had been used." | 3.69 | Acute severe depression following peri-operative ondansetron. ( Blaine, EM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiernan, E | 1 |
| Jones, KL | 1 |
| Kurhe, Y | 2 |
| Radhakrishnan, M | 2 |
| Gupta, D | 2 |
| Johnson, BA | 1 |
| Sussman, N | 1 |
| Oren, DA | 1 |
| Kim, SW | 1 |
| Hoover, KM | 1 |
| Yatham, LN | 1 |
| Zis, AP | 1 |
| Lam, RW | 1 |
| Srisurapanont, M | 1 |
| McGarvey, K | 1 |
| Agbayewa, O | 1 |
| Blaine, EM | 1 |
| Raby, WN | 1 |
| Lara, DR | 1 |
| Busnello, ED | 1 |
| Souza, DO | 1 |
3 reviews available for ondansetron and Depressive Disorder
| Article | Year |
|---|---|
Medications that Cause Fetal Anomalies and Possible Prevention Strategies.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Analg | 2019 |
Medication treatment of different types of alcoholism.
Topics: Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Chronic Disease; Depressive Disorder; Female; | 2010 |
The potential benefits of serotonin receptor-specific agents.
Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Humans; Isoxazoles; Ondansetron; Piperazines; | 1994 |
2 trials available for ondansetron and Depressive Disorder
| Article | Year |
|---|---|
Tridimensional personality questionnaire: assessment in patients with social phobia and a control group.
Topics: Adult; Anti-Anxiety Agents; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Meth | 1996 |
Role of serotonin3 receptors in prolactin release induced by electroconvulsive therapy: a study with ondansetron.
Topics: Adult; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Electroconvulsive Therapy; Fema | 1996 |
6 other studies available for ondansetron and Depressive Disorder
| Article | Year |
|---|---|
Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Brain; Depression; Depressive Disor | 2014 |
Ondansetron, a 5HT3 receptor antagonist reverses depression and anxiety-like behavior in streptozotocin-induced diabetic mice: possible implication of serotonergic system.
Topics: Animals; Antidepressive Agents; Antiemetics; Anxiety; Behavior, Animal; Brain; Depression; Depressiv | 2014 |
Dysphoria after treatment with ondansetron.
Topics: Adult; Antineoplastic Agents; Depressive Disorder; Female; Humans; Nausea; Ondansetron | 1995 |
Acute severe depression following peri-operative ondansetron.
Topics: Adult; Depressive Disorder; Female; Humans; Nausea; Ondansetron; Premedication; Serotonin Antagonist | 1997 |
Treatment of venlafaxine discontinuation symptoms with ondansetron.
Topics: Adult; Cyclohexanols; Depressive Disorder; Female; Humans; Ondansetron; Selective Serotonin Reuptake | 1998 |
Ondansetron rather than metoclopramide for bupropion-induced nausea.
Topics: Adult; Antiemetics; Bupropion; Depressive Disorder; Drug Interactions; Female; Humans; Metoclopramid | 2001 |