Page last updated: 2024-11-01

ondansetron and Delayed Effects, Prenatal Exposure

ondansetron has been researched along with Delayed Effects, Prenatal Exposure in 7 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Literature is divided regarding the risk of neonatal ventricular septal defect (VSD) associated with first trimester ondansetron use in pregnancy."7.96Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect. ( Bodnar, LM; Caritis, SN; Garrard, W; Lemon, LS; Marroquin, OC; Platt, RW; Venkataramanan, R, 2020)
"Literature is divided regarding the risk of neonatal ventricular septal defect (VSD) associated with first trimester ondansetron use in pregnancy."3.96Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect. ( Bodnar, LM; Caritis, SN; Garrard, W; Lemon, LS; Marroquin, OC; Platt, RW; Venkataramanan, R, 2020)
"The exposed group (n = 143) was comprised of children whose mothers received promethazine or ondansetron during pregnancy."3.80Antiemetic medications in pregnancy: a prospective investigation of obstetric and neurobehavioral outcomes. ( Dajani, NK; Eswaran, H; Larrimer, MB; Newport, DJ; Siegel, ER; Stowe, ZN, 2014)
" The experience with mitoxantrone (MIX) especially in the first trimenon is very limited, until now only one case of a pregnant woman with MS who was exposed to MIX in early pregnancy and delivered a growth restricted but healthy child was published."3.77A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosis. ( Chan, A; Epplen, J; Gold, R; Hellwig, K; Schimrigk, S, 2011)
"The role of peripheral 5-HT3 receptors in the nociceptive behavioral response and the effect of the 5-HT3 antagonist ondansetron on indices of acute and tonic pain were investigated in the formalin test in 25- and 90-day-old Wistar male rats."3.74[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress]. ( Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA, 2007)
"Ondansetron is a 5HT3 receptor antagonist widely used to treat hyperemesis gravidarum, although its safety is still questionable."1.91Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats. ( Aquino, AM; Arena, AC; Jorge, BC; Kassuya, CAL; Manoel, BM; Moreira, SDS; Reis, ACC; Scarano, WR; Stein, J; Valente, LC, 2023)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Reis, ACC3
Jorge, BC3
Stein, J3
Moreira, SDS3
Manoel, BM3
Aquino, AM3
Valente, LC3
Kassuya, CAL3
Scarano, WR3
Arena, AC3
Lemon, LS1
Bodnar, LM1
Garrard, W1
Venkataramanan, R1
Platt, RW1
Marroquin, OC1
Caritis, SN1
Larrimer, MB1
Dajani, NK1
Siegel, ER1
Eswaran, H1
Newport, DJ1
Stowe, ZN1
Kamendi, HW1
Cheng, Q1
Dergacheva, O1
Gorini, C1
Jameson, HS1
Wang, X1
McIntosh, JM1
Mendelowitz, D1
Hellwig, K1
Schimrigk, S1
Chan, A1
Epplen, J1
Gold, R1
Butkevich, IP1
Mikhaĭlenko, VA1
Makukhina, GV1
Kwon, P1
Lefkowitz, W1

Other Studies

7 other studies available for ondansetron and Delayed Effects, Prenatal Exposure

ArticleYear
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 137

    Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo

2023
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 137

    Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo

2023
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 137

    Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo

2023
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 137

    Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo

2023
Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect.
    International journal of epidemiology, 2020, 04-01, Volume: 49, Issue:2

    Topics: Female; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Ondansetron; Pregnancy; Pregnanc

2020
Antiemetic medications in pregnancy: a prospective investigation of obstetric and neurobehavioral outcomes.
    American journal of obstetrics and gynecology, 2014, Volume: 210, Issue:3

    Topics: Adult; Antiemetics; Child Development; Female; Humans; Infant, Newborn; Longitudinal Studies; Male;

2014
Abolishment of serotonergic neurotransmission to cardiac vagal neurons during and after hypoxia and hypercapnia with prenatal nicotine exposure.
    Journal of neurophysiology, 2009, Volume: 101, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Conotoxins; Dose

2009
A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosis.
    Journal of the neurological sciences, 2011, Aug-15, Volume: 307, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Antineoplastic Agents; Female; Humans; Infant, Newb

2011
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:2

    Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy;

2007
Neonatal extrapyramidal movements. Neonatal withdrawal due to maternal citalopram and ondansetron use.
    Pediatric annals, 2008, Volume: 37, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Basal Ganglia Diseases; Citalopram; Female; Humans; Infant, Newborn; Lor

2008