ondansetron has been researched along with Crohn Disease in 2 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methotrexate (MTX) is an effective treatment for Crohn disease (CD); however, its application may be limited by the occurrence of nausea." | 7.77 | Short-course ondansetron for the prevention of methotrexate-induced nausea in children with Crohn disease. ( Barkey, J; Benchimol, EI; Boland, M; Kempinska, A; Mack, A; Mack, DR, 2011) |
| "Methotrexate (MTX) is an effective treatment for Crohn disease (CD); however, its application may be limited by the occurrence of nausea." | 3.77 | Short-course ondansetron for the prevention of methotrexate-induced nausea in children with Crohn disease. ( Barkey, J; Benchimol, EI; Boland, M; Kempinska, A; Mack, A; Mack, DR, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomollón, F | 1 |
| Rubio, S | 1 |
| Charro, M | 1 |
| García-López, S | 1 |
| Muñoz, F | 1 |
| Gisbert, JP | 1 |
| Domènech, E | 1 |
| Kempinska, A | 1 |
| Benchimol, EI | 1 |
| Mack, A | 1 |
| Barkey, J | 1 |
| Boland, M | 1 |
| Mack, DR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis[NCT04169828] | 176 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for ondansetron and Crohn Disease
| Article | Year |
|---|---|
[Reccomendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the use of methotrexate in inflammatory bowel disease].
Topics: Adult; Antiemetics; Antirheumatic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Inju | 2015 |
Short-course ondansetron for the prevention of methotrexate-induced nausea in children with Crohn disease.
Topics: Adolescent; Case-Control Studies; Child; Crohn Disease; Dose-Response Relationship, Drug; Female; Hu | 2011 |