ondansetron has been researched along with Colitis, Mucous in 19 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS-D)." | 9.41 | Randomised, placebo-controlled trial and meta-analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial. ( Akbar, A; Aziz, Q; Barnard, L; Brindle, R; Corsetti, M; Dinning, PG; Eugenicos, M; Farmer, A; Farrin, AJ; Ford, AC; Fried, R; Gunn, D; Holloway, I; Houghton, L; Kapur, K; Mclaughlin, J; Sanders, D; Scott, M; Spiller, R; Topan, R; Trudgill, N; Whorwell, P, 2023) |
| "Previous, small studies have suggested that ondansetron has beneficial effects in diarrhea-predominant irritable bowel syndrome (IBS-D)." | 9.34 | Bimodal Release Ondansetron Improves Stool Consistency and Symptomatology in Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized, Double-Blind, Trial. ( Abramson, D; Barton, G; Davidson, E; Fathi, R; Harris, MS; Kalfus, I; Plasse, TF; Raday, G, 2020) |
| "There is a clear unmet need for new treatments in irritable bowel syndrome with diarrhea (IBS-D)." | 5.56 | Positive Effect of Bimodal Release Ondansetron in Irritable Bowel Syndrome With Diarrhea: Relevance of Low-Grade Inflammation? ( Melchior, C; Simrén, M, 2020) |
| "Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS-D)." | 5.41 | Randomised, placebo-controlled trial and meta-analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial. ( Akbar, A; Aziz, Q; Barnard, L; Brindle, R; Corsetti, M; Dinning, PG; Eugenicos, M; Farmer, A; Farrin, AJ; Ford, AC; Fried, R; Gunn, D; Holloway, I; Houghton, L; Kapur, K; Mclaughlin, J; Sanders, D; Scott, M; Spiller, R; Topan, R; Trudgill, N; Whorwell, P, 2023) |
| "Previous, small studies have suggested that ondansetron has beneficial effects in diarrhea-predominant irritable bowel syndrome (IBS-D)." | 5.34 | Bimodal Release Ondansetron Improves Stool Consistency and Symptomatology in Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized, Double-Blind, Trial. ( Abramson, D; Barton, G; Davidson, E; Fathi, R; Harris, MS; Kalfus, I; Plasse, TF; Raday, G, 2020) |
| "There is a clear unmet need for new treatments in irritable bowel syndrome with diarrhea (IBS-D)." | 1.56 | Positive Effect of Bimodal Release Ondansetron in Irritable Bowel Syndrome With Diarrhea: Relevance of Low-Grade Inflammation? ( Melchior, C; Simrén, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 7 (36.84) | 2.80 |
| Authors | Studies |
|---|---|
| Manning, DD | 1 |
| Cioffi, CL | 1 |
| Usyatinsky, A | 1 |
| Fitzpatrick, K | 1 |
| Masih, L | 1 |
| Guo, C | 1 |
| Zhang, Z | 1 |
| Choo, SH | 1 |
| Sikkander, MI | 1 |
| Ryan, KN | 1 |
| Naginskaya, J | 1 |
| Hassler, C | 1 |
| Dobritsa, S | 1 |
| Wierschke, JD | 1 |
| Earley, WG | 1 |
| Butler, AS | 1 |
| Brady, CA | 1 |
| Barnes, NM | 1 |
| Cohen, ML | 1 |
| Guzzo, PR | 1 |
| Gunn, D | 5 |
| Topan, R | 1 |
| Barnard, L | 1 |
| Fried, R | 2 |
| Holloway, I | 2 |
| Brindle, R | 1 |
| Corsetti, M | 2 |
| Scott, M | 2 |
| Farmer, A | 2 |
| Kapur, K | 2 |
| Sanders, D | 2 |
| Eugenicos, M | 2 |
| Trudgill, N | 2 |
| Whorwell, P | 5 |
| Mclaughlin, J | 2 |
| Akbar, A | 2 |
| Houghton, L | 2 |
| Dinning, PG | 2 |
| Aziz, Q | 2 |
| Ford, AC | 6 |
| Farrin, AJ | 1 |
| Spiller, R | 6 |
| Shah, ED | 1 |
| Ford, A | 1 |
| Farrin, A | 2 |
| Lalani, R | 1 |
| Morris, T | 1 |
| Olivier, C | 1 |
| Kearns, R | 1 |
| Emmanuel, A | 1 |
| Yiannakou, Y | 1 |
| Black, CJ | 2 |
| Houghton, LA | 1 |
| Garsed, K | 3 |
| Lam, C | 3 |
| Singh, G | 3 |
| Lingaya, M | 2 |
| Wahl, V | 2 |
| Niesler, B | 2 |
| Henry, A | 3 |
| Hall, I | 2 |
| Plasse, TF | 2 |
| Barton, G | 1 |
| Davidson, E | 1 |
| Abramson, D | 1 |
| Kalfus, I | 1 |
| Fathi, R | 1 |
| Raday, G | 1 |
| Harris, MS | 1 |
| Melchior, C | 1 |
| Simrén, M | 1 |
| Hall, IP | 1 |
| Chernova, J | 1 |
| Hastings, M | 1 |
| Marciani, L | 2 |
| Barbara, G | 1 |
| Luthra, P | 2 |
| Levy, R | 1 |
| Corbo, J | 1 |
| Prasad, S | 1 |
| Wright, J | 1 |
| Foley, S | 1 |
| Hoad, CL | 1 |
| Totman, JJ | 1 |
| Bush, D | 1 |
| Hartley, C | 1 |
| Armstrong, A | 1 |
| Manby, P | 1 |
| Blackshaw, E | 1 |
| Perkins, AC | 1 |
| Gowland, PA | 1 |
| Spiller, RC | 1 |
| Dizdar, V | 1 |
| Gilja, OH | 1 |
| Hausken, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised, Placebo Controlled Trial to Determine the Efficacy and Mode of Action of Ondansetron in the Treatment of Irritable Bowel Syndrome With Diarrhoea[NCT03555188] | Phase 3 | 80 participants (Actual) | Interventional | 2018-03-29 | Completed | ||
| Effect of Physical Form of Apples on Gastrointestinal Function and Satiety: a MRI Study[NCT03714464] | 31 participants (Actual) | Interventional | 2016-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ondansetron and Colitis, Mucous
| Article | Year |
|---|---|
Randomised, placebo-controlled trial and meta-analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial.
Topics: Diarrhea; Double-Blind Method; Feces; Humans; Irritable Bowel Syndrome; Ondansetron; Randomized Cont | 2023 |
5 trials available for ondansetron and Colitis, Mucous
| Article | Year |
|---|---|
Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study protocol for a randomised controlled trial.
Topics: Antidiarrheals; Clinical Trials, Phase III as Topic; Diarrhea; Double-Blind Method; Humans; Irritabl | 2019 |
Bimodal Release Ondansetron Improves Stool Consistency and Symptomatology in Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized, Double-Blind, Trial.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Defecation; Diarrhea; Double-Blind Method; Female; Gastroin | 2020 |
Abnormalities of mucosal serotonin metabolism and 5-HT
Topics: Adult; Cross-Over Studies; Diarrhea; Female; Genotype; Humans; Intestinal Mucosa; Irritable Bowel Sy | 2019 |
A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea.
Topics: Adult; Cross-Over Studies; Diarrhea; Double-Blind Method; Feces; Female; Humans; Irritable Bowel Syn | 2014 |
Increased visceral sensitivity in Giardia-induced postinfectious irritable bowel syndrome and functional dyspepsia. Effect of the 5HT3-antagonist ondansetron.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Dyspepsia; Female; Gastric Emptying; Giardiasis; Human | 2007 |
13 other studies available for ondansetron and Colitis, Mucous
| Article | Year |
|---|---|
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
Topics: Animals; Cell Line; Disease Models, Animal; Humans; Imidazoles; Indoles; Irritable Bowel Syndrome; M | 2011 |
Editorial: ondansetron for patients with IBS-D and bowel-predominant symptoms.
Topics: Humans; Irritable Bowel Syndrome; Ondansetron | 2023 |
Editorial: ondansetron for patients with IBS-D and bowel-predominant symptoms-authors' reply.
Topics: Humans; Irritable Bowel Syndrome; Ondansetron | 2023 |
Editorial: understanding differences in patient response to ondansetron in irritable bowel syndrome with diarrhoea-are we any closer?
Topics: Diarrhea; Humans; Irritable Bowel Syndrome; Ondansetron; Receptors, Serotonin, 5-HT3; Serotonin | 2019 |
Editorial: understanding differences in patient response to ondansetron in irritable bowel syndrome with diarrhoea-are we any closer? Authors' reply.
Topics: Diarrhea; Humans; Irritable Bowel Syndrome; Ondansetron; Receptors, Serotonin, 5-HT3; Serotonin | 2019 |
Positive Effect of Bimodal Release Ondansetron in Irritable Bowel Syndrome With Diarrhea: Relevance of Low-Grade Inflammation?
Topics: Diarrhea; Double-Blind Method; Humans; Inflammation; Irritable Bowel Syndrome; Ondansetron | 2020 |
Reply to Black and Ford.
Topics: Diarrhea; Double-Blind Method; Humans; Irritable Bowel Syndrome; Ondansetron | 2021 |
Efficacy of Ondansetron for Irritable Bowel Syndrome With Diarrhea.
Topics: Diarrhea; Double-Blind Method; Humans; Irritable Bowel Syndrome; Ondansetron | 2021 |
Revival of 5-HT3 antagonism as treatment of IBS-D?
Topics: Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; Ondansetron; Serotonin Antagonists | 2014 |
Ondansetron and irritable bowel syndrome.
Topics: Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; Ondansetron; Serotonin Antagonists | 2015 |
The fall and rise of 5-hydroxytryptamine receptor antagonists in irritable bowel syndrome with diarrhea.
Topics: Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; Ondansetron; Serotonin Antagonists | 2014 |
An antiemetic for irritable bowel syndrome?
Topics: Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; Ondansetron; Serotonin Antagonists | 2014 |
Effects of a 5-HT(3) antagonist, ondansetron, on fasting and postprandial small bowel water content assessed by magnetic resonance imaging.
Topics: Adolescent; Adult; Aged; Diarrhea; Fasting; Female; Humans; Irritable Bowel Syndrome; Magnetic Reson | 2010 |