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ondansetron and Chronic Illness

ondansetron has been researched along with Chronic Illness in 12 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Under double-blind, randomized conditions, 121 treatment-resistant inpatients with chronic DSM-IV-diagnosed schizophrenia received haloperidol (4-30 mg/day) combined with either placebo (N=63) or a fixed dose of 8 mg/day of ondansetron (N=58) for 12 weeks."9.12Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: a double-blind, randomized, placebo-controlled study. ( Kang, WH; Li, Q; Ma, AQ; Wang, XY; Yao, SM; Zhang, ZJ, 2006)
"Seventeen patients with severe pruritus complicating established chronic liver disease were randomized to receive, double-blind, ondansetron (8 mg) or a placebo orally; each was administered thrice daily for a 4-week period."9.12Ondansetron and pruritus in chronic liver disease: a controlled study. ( Jones, EA; Molenaar, HA; Oosting, J, 2007)
"Recently, the serotonin antagonist ondansetron has been reported to have a positive effect on cholestasis-associated pruritus."9.08Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial. ( Ferenci, P; Kaider, A; Müller, C; Penner, E; Pidlich, J; Pongratz, S; Raderer, M; Scheithauer, W; Schemper, M, 1998)
"When treating nausea in patients with chronic gastrointestinal syndromes, clinicians may consider trying higher performing treatments first, and forgoing lower performing treatments."5.56Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea. ( Clarke, JO; Fernandez-Becker, N; Garcia, M; Garcia, P; Grewal, D; Kamal, A; Nandwani, M; Neshatian, L; Nguyen, L; Okafor, P; Regalia, K; Sonu, I; Triadafilopoulos, G; Zikos, TA, 2020)
"Under double-blind, randomized conditions, 121 treatment-resistant inpatients with chronic DSM-IV-diagnosed schizophrenia received haloperidol (4-30 mg/day) combined with either placebo (N=63) or a fixed dose of 8 mg/day of ondansetron (N=58) for 12 weeks."5.12Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: a double-blind, randomized, placebo-controlled study. ( Kang, WH; Li, Q; Ma, AQ; Wang, XY; Yao, SM; Zhang, ZJ, 2006)
"Seventeen patients with severe pruritus complicating established chronic liver disease were randomized to receive, double-blind, ondansetron (8 mg) or a placebo orally; each was administered thrice daily for a 4-week period."5.12Ondansetron and pruritus in chronic liver disease: a controlled study. ( Jones, EA; Molenaar, HA; Oosting, J, 2007)
"Recently, the serotonin antagonist ondansetron has been reported to have a positive effect on cholestasis-associated pruritus."5.08Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial. ( Ferenci, P; Kaider, A; Müller, C; Penner, E; Pidlich, J; Pongratz, S; Raderer, M; Scheithauer, W; Schemper, M, 1998)
"When treating nausea in patients with chronic gastrointestinal syndromes, clinicians may consider trying higher performing treatments first, and forgoing lower performing treatments."1.56Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea. ( Clarke, JO; Fernandez-Becker, N; Garcia, M; Garcia, P; Grewal, D; Kamal, A; Nandwani, M; Neshatian, L; Nguyen, L; Okafor, P; Regalia, K; Sonu, I; Triadafilopoulos, G; Zikos, TA, 2020)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Suhas, S1
Malo, PK1
Kumar, V1
Issac, TG1
Chithra, NK1
Bhaskarapillai, B1
Reddy, YCJ1
Rao, NP1
Zikos, TA1
Nguyen, L1
Kamal, A1
Fernandez-Becker, N1
Regalia, K1
Nandwani, M1
Sonu, I1
Garcia, M1
Okafor, P1
Neshatian, L1
Grewal, D1
Garcia, P1
Triadafilopoulos, G1
Clarke, JO1
Akhondzadeh, S1
Mohammadi, N1
Noroozian, M1
Karamghadiri, N1
Ghoreishi, A1
Jamshidi, AH1
Forghani, S1
Johnson, BA1
Song, MY1
Ku, SK1
Kim, HJ1
Han, JS1
Zhang, ZJ1
Kang, WH1
Li, Q1
Wang, XY1
Yao, SM1
Ma, AQ1
Frigon, C1
Desparmet, J1
Jones, EA1
Molenaar, HA1
Oosting, J1
Trioche, P1
Samuel, D1
Odièvre, M1
Labrune, P1
Briskin, JK1
Curtis, JL1
Müller, C1
Pongratz, S1
Pidlich, J1
Penner, E1
Kaider, A1
Schemper, M1
Raderer, M1
Scheithauer, W1
Ferenci, P1
Kiss, A1

Reviews

2 reviews available for ondansetron and Chronic Illness

ArticleYear
Treatment strategies for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A network meta-analysis of randomised controlled trials.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2023, Volume: 24, Issue:2

    Topics: Adult; Aripiprazole; Child; Chronic Disease; Humans; Network Meta-Analysis; Obsessive-Compulsive Dis

2023
Medication treatment of different types of alcoholism.
    The American journal of psychiatry, 2010, Volume: 167, Issue:6

    Topics: Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Chronic Disease; Depressive Disorder; Female;

2010

Trials

4 trials available for ondansetron and Chronic Illness

ArticleYear
Added ondansetron for stable schizophrenia: a double blind, placebo controlled trial.
    Schizophrenia research, 2009, Volume: 107, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Case-Control Studies; Chronic Disease; Cognition Disorders; Double-Blin

2009
Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: a double-blind, randomized, placebo-controlled study.
    Schizophrenia research, 2006, Volume: 88, Issue:1-3

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chronic Disease; Diagnostic and Statistical Manual of

2006
Ondansetron and pruritus in chronic liver disease: a controlled study.
    Hepato-gastroenterology, 2007, Volume: 54, Issue:76

    Topics: Adolescent; Adult; Aged; Antipruritics; Chronic Disease; Double-Blind Method; Female; Humans; Liver

2007
Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:10

    Topics: Administration, Oral; Adult; Aged; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female;

1998

Other Studies

6 other studies available for ondansetron and Chronic Illness

ArticleYear
Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Cannabis; Chronic Disease; Comparative Effe

2020
Low molecular weight fucoidan ameliorating the chronic cisplatin-induced delayed gastrointestinal motility in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:12

    Topics: Animals; Antineoplastic Agents; Antioxidants; Chronic Disease; Cisplatin; Enterochromaffin Cells; Ga

2012
Ondansetron treatment in a child presenting with chronic intractable pruritus.
    Pain research & management, 2006,Winter, Volume: 11, Issue:4

    Topics: Antipruritics; Child; Chronic Disease; Humans; Male; Ondansetron; Pruritus

2006
Ondansetron for pruritus in child with chronic cholestasis.
    European journal of pediatrics, 1996, Volume: 155, Issue:11

    Topics: Alagille Syndrome; Child, Preschool; Cholestasis; Chronic Disease; Female; Humans; Ondansetron; Prur

1996
Augmentation of clozapine therapy with ondansetron.
    The American journal of psychiatry, 1997, Volume: 154, Issue:8

    Topics: Adult; Animals; Chronic Disease; Clozapine; Drug Synergism; Drug Therapy, Combination; Humans; Male;

1997
Treatment of chronic bulimic symptoms: new answers, more questions.
    Lancet (London, England), 2000, Mar-04, Volume: 355, Issue:9206

    Topics: Antiemetics; Bulimia; Chronic Disease; Female; Follow-Up Studies; Humans; Ondansetron; Serotonin Ant

2000