ondansetron has been researched along with Cholestasis in 10 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 9.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 9.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus." | 8.88 | The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012) |
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 5.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 5.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus." | 4.88 | The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012) |
| "Primary biliary cirrhosis (PBC), autoimmune cholangitis (AIC = AMA-negative PBC) and primary sclerosing cholangitis (PSC) are autoimmune cholestatic liver diseases." | 2.42 | [Cholestatic liver diseases]. ( Blum, HE; Kreisel, W; Opitz, OG; Thimme, R, 2004) |
| "The treatment with ondansetron may also have effects on the pruritus of patients with cholestasis." | 1.32 | [Pathogenesis and treatment of pruritus in patients with cholestasis]. ( Blumenstein, I; Schirrmacher, S; Stein, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| To, TH | 1 |
| Clark, K | 1 |
| Lam, L | 1 |
| Shelby-James, T | 1 |
| Currow, DC | 1 |
| Schirrmacher, S | 1 |
| Blumenstein, I | 1 |
| Stein, J | 1 |
| Thimme, R | 1 |
| Opitz, OG | 1 |
| Blum, HE | 1 |
| Kreisel, W | 1 |
| O'Donohue, JW | 1 |
| Pereira, SP | 1 |
| Ashdown, AC | 1 |
| Haigh, CG | 1 |
| Wilkinson, JR | 1 |
| Williams, R | 1 |
| Schwörer, H | 2 |
| Hartmann, H | 1 |
| Ramadori, G | 2 |
| Raderer, M | 1 |
| Müller, C | 1 |
| Scheithauer, W | 1 |
| Quigley, C | 1 |
| Trioche, P | 1 |
| Samuel, D | 1 |
| Odièvre, M | 1 |
| Labrune, P | 1 |
| Lamelo Alfonsín, F | 1 |
| Vila Arias, M | 1 |
| San Martín Moreira, J | 1 |
| Silva César, M | 1 |
2 reviews available for ondansetron and Cholestasis
| Article | Year |
|---|---|
The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review.
Topics: Adult; Aged; Aged, 80 and over; Cholestasis; Female; Humans; Male; Middle Aged; Ondansetron; Pruritu | 2012 |
[Cholestatic liver diseases].
Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruriti | 2004 |
2 trials available for ondansetron and Cholestasis
| Article | Year |
|---|---|
A controlled trial of ondansetron in the pruritus of cholestasis.
Topics: Adult; Aged; Aged, 80 and over; Antipruritics; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary | 2005 |
Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.
Topics: Adult; Aged; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; M | 1995 |
6 other studies available for ondansetron and Cholestasis
| Article | Year |
|---|---|
[Pathogenesis and treatment of pruritus in patients with cholestasis].
Topics: Brain; Cholestasis; Cholestyramine Resin; Dronabinol; Enzyme Induction; Humans; Liver; Narcotic Anta | 2003 |
Improvement of cholestatic pruritus by ondansetron.
Topics: Cholestasis; Female; Humans; Middle Aged; Ondansetron; Pruritus | 1993 |
Ondansetron for pruritus due to cholestasis.
Topics: Cholestasis; Female; Humans; Male; Ondansetron; Pruritus | 1994 |
5HT3 receptor antagonists and pruritus due to cholestasis.
Topics: Aged; Breast Neoplasms; Cholestasis; Female; Granisetron; Humans; Liver Neoplasms; Ondansetron; Prur | 1996 |
Ondansetron for pruritus in child with chronic cholestasis.
Topics: Alagille Syndrome; Child, Preschool; Cholestasis; Chronic Disease; Female; Humans; Ondansetron; Prur | 1996 |
[Ondansetron for cholestatic pruritus].
Topics: Aged; Cholestasis; Humans; Male; Ondansetron; Pruritus; Serotonin Antagonists | 1998 |