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ondansetron and Cholangitis, Sclerosing

ondansetron has been researched along with Cholangitis, Sclerosing in 2 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)."9.08Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995)
"The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)."5.08Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995)
"Primary biliary cirrhosis (PBC), autoimmune cholangitis (AIC = AMA-negative PBC) and primary sclerosing cholangitis (PSC) are autoimmune cholestatic liver diseases."2.42[Cholestatic liver diseases]. ( Blum, HE; Kreisel, W; Opitz, OG; Thimme, R, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thimme, R1
Opitz, OG1
Blum, HE1
Kreisel, W1
Schwörer, H1
Hartmann, H1
Ramadori, G1

Reviews

1 review available for ondansetron and Cholangitis, Sclerosing

ArticleYear
[Cholestatic liver diseases].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:8

    Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruriti

2004

Trials

1 trial available for ondansetron and Cholangitis, Sclerosing

ArticleYear
Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.
    Pain, 1995, Volume: 61, Issue:1

    Topics: Adult; Aged; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; M

1995