ondansetron has been researched along with Chemical and Drug Induced Liver Injury in 11 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Together with these new biomarkers of hepatotoxicity, a 12-hour acetylcysteine protocol offers clinicians and patients the possibility for better targeting of therapy, fewer adverse effects, a simpler dosing regimen, and shorter hospital stay." | 1.42 | Changing the Management of Paracetamol Poisoning. ( Bateman, DN, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Gomollón, F | 1 |
| Rubio, S | 1 |
| Charro, M | 1 |
| García-López, S | 1 |
| Muñoz, F | 1 |
| Gisbert, JP | 1 |
| Domènech, E | 1 |
| Bateman, DN | 2 |
| Vliegenthart, A | 1 |
| Kimmitt, RA | 1 |
| Seymour, JH | 1 |
| Homer, NZ | 1 |
| Clarke, JI | 1 |
| Eddleston, M | 1 |
| Gray, A | 1 |
| Wood, DM | 1 |
| Dargan, PI | 1 |
| Cooper, JG | 1 |
| Antoine, DJ | 1 |
| Webb, DJ | 1 |
| Lewis, SC | 1 |
| Dear, JW | 1 |
| Janeiro, M | 1 |
| Camblor, E | 1 |
| Fernández, R | 1 |
| Núñez, D | 1 |
| Kosmidis, PA | 1 |
| Kalofonos, HP | 1 |
| Christodoulou, C | 1 |
| Syrigos, K | 1 |
| Makatsoris, T | 1 |
| Skarlos, D | 1 |
| Bakogiannis, C | 1 |
| Nicolaides, C | 1 |
| Bafaloukos, D | 1 |
| Bamias, A | 1 |
| Samantas, E | 1 |
| Xiros, N | 1 |
| Boukovinas, I | 1 |
| Fountzilas, G | 1 |
| Dimopoulos, MA | 1 |
| Hall, TJ | 1 |
| James, PR | 1 |
| Cambridge, G | 1 |
1 review available for ondansetron and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
1 trial available for ondansetron and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2008 |
9 other studies available for ondansetron and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
[Reccomendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the use of methotrexate in inflammatory bowel disease].
Topics: Adult; Antiemetics; Antirheumatic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Inju | 2015 |
Changing the Management of Paracetamol Poisoning.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Anaphylaxis; Antidotes; Antiemetics; Biomar | 2015 |
Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury.
Topics: Acetaminophen; Acetylcysteine; Adult; Alanine Transaminase; Analgesics, Non-Narcotic; Antiemetics; A | 2017 |
[Narcolepsy and anesthesia].
Topics: Analgesia, Epidural; Anesthesia, Intravenous; Antiemetics; Benzhydryl Compounds; Chemical and Drug I | 2007 |
Development of an in vitro hepatotoxicity assay for assessing the effects of chronic drug exposure.
Topics: Acetaminophen; Amitriptyline; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Hu | 1993 |