Page last updated: 2024-11-01

ondansetron and Cerebral Concussion

ondansetron has been researched along with Cerebral Concussion in 4 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Assess the feasibility of a study evaluating one dose of oral ondansetron to decrease post-concussion symptoms at one week and one month following concussion in children aged 8 to 17 years old."5.24Ondansetron for pediatric concussion; a pilot study for a randomized controlled trial. ( Beauchamp, MH; Carrière, B; Crevier, L; D'Angelo, A; Gravel, J; Mâsse, B, 2017)
"In children presenting to the ED with an acute concussion, ondansetron use was associated with a higher risk of persistent post-concussion symptoms at 1 month."3.91Association between ondansetron use and symptom persistence in children with concussions: A 5P substudy. ( Beauchamp, MH; Boutis, K; Dubrovsky, AS; Freedman, SB; Gagnon, I; Gravel, J; Momoli, F; Tang, K; Zemek, R, 2019)
"Many TBI victims experience chronic pain."1.72Monoamine control of descending pain modulation after mild traumatic brain injury. ( Clark, JD; Irvine, KA; Sahbaie, P; Shi, XY, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Sahbaie, P1
Irvine, KA1
Shi, XY1
Clark, JD1
Standiford, L1
O'Daniel, M1
Hysell, M1
Trigger, C1
Gravel, J2
Boutis, K1
Tang, K1
Beauchamp, MH2
Freedman, SB1
Dubrovsky, AS1
Gagnon, I1
Momoli, F1
Zemek, R1
Carrière, B1
D'Angelo, A1
Crevier, L1
Mâsse, B1

Trials

2 trials available for ondansetron and Cerebral Concussion

ArticleYear
A randomized cohort study of the efficacy of PO magnesium in the treatment of acute concussions in adolescents.
    The American journal of emergency medicine, 2021, Volume: 44

    Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Antiemetics; Brain Concus

2021
Ondansetron for pediatric concussion; a pilot study for a randomized controlled trial.
    CJEM, 2017, Volume: 19, Issue:5

    Topics: Administration, Oral; Adolescent; Brain Concussion; Child; Double-Blind Method; Emergency Service, H

2017

Other Studies

2 other studies available for ondansetron and Cerebral Concussion

ArticleYear
Monoamine control of descending pain modulation after mild traumatic brain injury.
    Scientific reports, 2022, 09-29, Volume: 12, Issue:1

    Topics: Amines; Animals; Brain Concussion; Brain Injuries, Traumatic; Chronic Pain; Duloxetine Hydrochloride

2022
Association between ondansetron use and symptom persistence in children with concussions: A 5P substudy.
    CJEM, 2019, Volume: 21, Issue:2

    Topics: Adolescent; Antiemetics; Brain Concussion; Canada; Child; Child, Preschool; Cohort Studies; Emergenc

2019