ondansetron has been researched along with Bradycardia in 15 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of prophylactic ondansetron on spinal anesthesia-induced hypotension and bradycardia among patients undergoing elective cesarean deliveries." | 9.22 | Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt. ( El Khouly, NI; Meligy, AM, 2016) |
| "The effect of a single intravenous dose of ondansetron in preventing postoperative nausea and emesis (retching and vomiting) (PONV) was investigated in a randomized, double-blind, placebo-controlled, multicentre, international study." | 9.07 | A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. ( Abrahamsson, J; Briggs, L; Forrler, M; Hellstern, K; Helmers, JH; Moodley, J; Soni, J, 1993) |
| "This study showed the effectiveness of the prescription of 5 mg ephedrine two minutes before changing from the lithotomy position to the supine in maintaining hemodynamic stability, reducing hypotension, bradycardia, nausea, and vomiting, and the amount of prescribed ephedrine, atropine, and ondansetron." | 5.69 | The Prophylaxis Effect of Ephedrine on Hemodynamic Variation in Patients Undergoing Percutaneous Nephrolithotomy Surgery with Spinal Anesthesia. ( Bahrami, A; Darvishzadehdaledari, S; Golabi, P; Hamoud Alshahrani, S; Kamalov, Z; Kazemi Haki, B; Nasiri, AA; Sajid Abdulabbas, H; Sane, S, 2023) |
| "To evaluate the effect of prophylactic ondansetron on spinal anesthesia-induced hypotension and bradycardia among patients undergoing elective cesarean deliveries." | 5.22 | Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt. ( El Khouly, NI; Meligy, AM, 2016) |
| "The effect of a single intravenous dose of ondansetron in preventing postoperative nausea and emesis (retching and vomiting) (PONV) was investigated in a randomized, double-blind, placebo-controlled, multicentre, international study." | 5.07 | A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. ( Abrahamsson, J; Briggs, L; Forrler, M; Hellstern, K; Helmers, JH; Moodley, J; Soni, J, 1993) |
| "Ondansetron has a preventive effect on PAS without a paralleled side effect of bradycardia." | 4.90 | Efficacy and safety of ondansetron in preventing postanesthesia shivering: a meta-analysis of randomized controlled trials. ( He, K; Liang, SR; Mou, JH; Su, GZ; Tie, HT; Yuan, HW, 2014) |
| "The potency of Ondansetron (Zofran, Glaxo), a highly specific 5HT3 antagonist in preventing the very unfavorable complication during introducing anesthesia, i." | 3.68 | Evaluation of ondansetron as a drug for premedication. ( Kamenova, E, 1993) |
| "pretreatment with capsazepine, ondansetron or HC030031." | 1.40 | Linalool-rich rosewood oil induces vago-vagal bradycardic and depressor reflex in rats. ( Correia Junior, CA; da Cunha, PJ; da Silva, MT; de Siqueira, RJ; dos Santos, AA; Duarte, GP; Lahlou, S; Magalhães, PJ; Maia, JG; Rodrigues, KM, 2014) |
| ") displaced the 5-HT dose-response curve to the right, with apparent DR2 values of 0." | 1.29 | Serotonin (5-HT)3-receptor antagonism of 4,5,6,7-tetrahydrobenzimidazole derivatives against 5-HT-induced bradycardia in anesthetized rats. ( Honda, K; Ito, H; Kamato, T; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sane, S | 1 |
| Nasiri, AA | 1 |
| Bahrami, A | 1 |
| Kamalov, Z | 1 |
| Hamoud Alshahrani, S | 1 |
| Sajid Abdulabbas, H | 1 |
| Darvishzadehdaledari, S | 1 |
| Golabi, P | 1 |
| Kazemi Haki, B | 1 |
| D Tubog, T | 1 |
| S Bramble, R | 1 |
| Zhou, C | 1 |
| Zhu, Y | 1 |
| Bao, Z | 1 |
| Wang, X | 1 |
| Liu, Q | 1 |
| Tubog, TD | 1 |
| Kane, TD | 1 |
| Pugh, MA | 1 |
| de Siqueira, RJ | 2 |
| Rodrigues, KM | 1 |
| da Silva, MT | 1 |
| Correia Junior, CA | 1 |
| Duarte, GP | 2 |
| Magalhães, PJ | 2 |
| dos Santos, AA | 1 |
| Maia, JG | 2 |
| da Cunha, PJ | 1 |
| Lahlou, S | 2 |
| Tie, HT | 1 |
| Su, GZ | 1 |
| He, K | 1 |
| Liang, SR | 1 |
| Yuan, HW | 1 |
| Mou, JH | 1 |
| El Khouly, NI | 1 |
| Meligy, AM | 1 |
| Macedo, FI | 1 |
| Interaminense, Lde F | 1 |
| Brito, TS | 1 |
| da Silva, JK | 1 |
| Sousa, PJ | 1 |
| Leal-Cardoso, JH | 1 |
| Eglen, RM | 1 |
| Lee, CH | 1 |
| Smith, WL | 1 |
| Johnson, LG | 1 |
| Clark, R | 1 |
| Whiting, RL | 1 |
| Hegde, SS | 1 |
| Yamano, M | 1 |
| Kamato, T | 1 |
| Nishida, A | 1 |
| Ito, H | 1 |
| Yuki, H | 1 |
| Tsutsumi, R | 1 |
| Honda, K | 1 |
| Miyata, K | 1 |
| Kamenova, E | 1 |
| Helmers, JH | 1 |
| Briggs, L | 1 |
| Abrahamsson, J | 1 |
| Soni, J | 1 |
| Moodley, J | 1 |
| Forrler, M | 1 |
| Hellstern, K | 1 |
| Harada, H | 1 |
| Morie, T | 1 |
| Hirokawa, Y | 1 |
| Terauchi, H | 1 |
| Fujiwara, I | 1 |
| Yoshida, N | 1 |
| Kato, S | 1 |
| Csillik-Perczel, V | 1 |
| Bakonyi, A | 1 |
| Yemane, T | 1 |
| Vitalis, B | 1 |
| Horvath, E | 1 |
| Solyom, S | 1 |
| Szekely, JI | 1 |
| Harsing, LG | 1 |
| Deshpande, SB | 1 |
| Bagchi, S | 1 |
| Rai, OP | 1 |
| Aryya, NC | 1 |
4 reviews available for ondansetron and Bradycardia
| Article | Year |
|---|---|
Ondansetron reduces the incidence of hypotension after spinal anaesthesia in non-caesarean delivery: A systematic review and meta-analysis.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Ephedrine; Humans; Hypotension; Incidence; | 2022 |
Efficacy of ondansetron for spinal anesthesia during cesarean section: a meta-analysis of randomized trials.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Bradycardia; Cesarean Section; Female; H | 2018 |
Effects of Ondansetron on Attenuating Spinal Anesthesia–Induced Hypotension and Bradycardia in Obstetric and Nonobstetric Subjects: A Systematic Review and Meta-Analysis.
Topics: Anesthesia, Spinal; Antiemetics; Bradycardia; Delivery, Obstetric; Female; Humans; Hypotension; Infu | 2017 |
Efficacy and safety of ondansetron in preventing postanesthesia shivering: a meta-analysis of randomized controlled trials.
Topics: Bradycardia; Humans; Ondansetron; Postoperative Complications; Randomized Controlled Trials as Topic | 2014 |
3 trials available for ondansetron and Bradycardia
| Article | Year |
|---|---|
The Prophylaxis Effect of Ephedrine on Hemodynamic Variation in Patients Undergoing Percutaneous Nephrolithotomy Surgery with Spinal Anesthesia.
Topics: Anesthesia, Spinal; Atropine; Bradycardia; Ephedrine; Hemodynamics; Humans; Hypotension; Nausea; Nep | 2023 |
Randomized controlled trial comparing ondansetron and placebo for the reduction of spinal anesthesia-induced hypotension during elective cesarean delivery in Egypt.
Topics: Administration, Intravenous; Adult; Anesthesia, Spinal; Blood Pressure; Bradycardia; Cesarean Sectio | 2016 |
A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Bradycardia; Constipation; Double-Blind Method; Female | 1993 |
8 other studies available for ondansetron and Bradycardia
| Article | Year |
|---|---|
Linalool-rich rosewood oil induces vago-vagal bradycardic and depressor reflex in rats.
Topics: Acetanilides; Acyclic Monoterpenes; Animals; Aorta; Atropine Derivatives; Blood Pressure; Bradycardi | 2014 |
1-Nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, elicits a vago-vagal bradycardiac and depressor reflex in normotensive rats.
Topics: Animals; Aorta; Atropine Derivatives; Benzene Derivatives; Bradycardia; Capsaicin; Cryptocarya; Dose | 2010 |
Pharmacological characterization of RS 25259-197, a novel and selective 5-HT3 receptor antagonist, in vivo.
Topics: Administration, Oral; Animals; Bradycardia; Dogs; Dose-Response Relationship, Drug; Duodenum; Female | 1995 |
Serotonin (5-HT)3-receptor antagonism of 4,5,6,7-tetrahydrobenzimidazole derivatives against 5-HT-induced bradycardia in anesthetized rats.
Topics: Animals; Benzimidazoles; Bradycardia; Colon; Disease Models, Animal; Dose-Response Relationship, Dru | 1994 |
Evaluation of ondansetron as a drug for premedication.
Topics: Adult; Aged; Anesthesia; Bradycardia; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; | 1993 |
Development of potent serotonin-3 (5-HT3) receptor antagonists. II. Structrue-activity relationships of N-(1-benzyl-4-methylhexahydro-1H-1,4- diazepin-6-yl)carboxamides.
Topics: Animals; Bradycardia; Granisetron; Injections, Intravenous; Magnetic Resonance Spectroscopy; Male; M | 1995 |
GYKI-46 903, a non-competitive antagonist for 5-HT3 receptors.
Topics: 5-Methoxytryptamine; Animals; Binding, Competitive; Bradycardia; Bridged Bicyclo Compounds, Heterocy | 1996 |
Pulmonary oedema produced by scorpion venom augments a phenyldiguanide-induced reflex response in anaesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Apnea; Aprotinin; Biguanides; Bradycardia; Drug Synergism; Female | 1999 |