ondansetron has been researched along with Body Weight in 18 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The weight-based dosing of ondansetron to reduce hypotension has never been investigated." | 9.27 | Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial. ( Dilokrattanaphijit, N; Karnjanawanichkul, O; Kunapaisal, T; Leeratiwong, J; Oofuvong, M, 2018) |
| " This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model." | 9.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| "The weight-based dosing of ondansetron to reduce hypotension has never been investigated." | 5.27 | Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial. ( Dilokrattanaphijit, N; Karnjanawanichkul, O; Kunapaisal, T; Leeratiwong, J; Oofuvong, M, 2018) |
| " This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model." | 5.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| " The rats were injected intraperitoneally with cisplatin to induce pica, and observe the effect of Armillariella tabescens on consumption of kaolin, food, water and body weight." | 3.77 | [Ameliorative effect of Armillariella tabescens on cisplatin-induced gastrointestinal tract reaction in the rat]. ( Du, J; Li, P; Sun, X; Zhang, M, 2011) |
| "The aim of the study was to learn whether the lethal and the motor incoordination (ataxia) side effect of ondansetron (Zophren) administration is dosing-time dependent." | 3.72 | Circadian rhythms in toxic effects of the serotonin antagonist ondansetron in mice. ( Ben Attia, M; Boughattas, NA; Bouzouita, K; Chouchane, L; Gadacha, W; Khedhaier, A; Mechkouri, M; Reinberg, A; Sani, M, 2003) |
| " In the present study, serotonin hydrochloride, buspirone (the serotonin 5-HT1A agonist) and ondensetron (the 5HT3 antagonist) were injected into nucleus caudatus through stereotaxically implanted cannulae in three different dosages (1, 2 and 5 microg) and their effects on 24 h food and water intake, and body weight were recorded." | 3.72 | Effects of injection of serotonin into nucleus caudatus on food and water intake and body weight in albino rats. ( Kannan, N; Pal, GK; Pal, P, 2004) |
| " The intervention group received intravenous ondansetron weight adjusted dosing at 0." | 2.90 | Comparison of weight-adjusted dose versus fixed dose ondansetron in preventing shivering following spinal anaesthesia for caesarean deliveries. ( Gicheru, M; Kabugi, J; Mir, S; Mung'ayi, V, 2019) |
| " These results should allow a better individualization of etoposide dosing in children." | 2.76 | Developmental pharmacokinetics of etoposide in 67 children: lack of dexamethasone effect. ( Auvrignon, A; Chastagner, P; Corradini, N; Doz, F; Gentet, JC; Giraud, C; Leblond, P; Rey, E; Rubie, H; Treluyer, JM; Urien, S; Vassal, G, 2011) |
| "Ondansetron is a 5HT3 receptor antagonist widely used to treat hyperemesis gravidarum, although its safety is still questionable." | 1.91 | Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats. ( Aquino, AM; Arena, AC; Jorge, BC; Kassuya, CAL; Manoel, BM; Moreira, SDS; Reis, ACC; Scarano, WR; Stein, J; Valente, LC, 2023) |
| " Blockade of serotonin (5-HT(3)) receptor signalling in the NTS by either the chronic administration of ondansetron or the genetic inactivation of Tph2 in caudal serotonergic neurons that project to the NTS protects against starvation when AgRP neurons are ablated." | 1.38 | Deciphering a neuronal circuit that mediates appetite. ( Clark, MS; Palmiter, RD; Wu, Q, 2012) |
| " These data support recent claims that GR38032F attenuates benzodiazepine withdrawal, and they indicate that this effect shows an inverted U-shaped dose-response curve." | 1.28 | Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats. ( Goudie, AJ; Leathley, MJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Reis, ACC | 3 |
| Jorge, BC | 3 |
| Stein, J | 3 |
| Moreira, SDS | 3 |
| Manoel, BM | 3 |
| Aquino, AM | 3 |
| Valente, LC | 3 |
| Kassuya, CAL | 3 |
| Scarano, WR | 3 |
| Arena, AC | 3 |
| Gicheru, M | 1 |
| Mung'ayi, V | 1 |
| Mir, S | 1 |
| Kabugi, J | 1 |
| Goodarzi, P | 1 |
| Habibi, M | 1 |
| Roberts, K | 1 |
| Sutton, J | 1 |
| Shili, CN | 1 |
| Lin, D | 1 |
| Pezeshki, A | 1 |
| Oofuvong, M | 1 |
| Kunapaisal, T | 1 |
| Karnjanawanichkul, O | 1 |
| Dilokrattanaphijit, N | 1 |
| Leeratiwong, J | 1 |
| Bodge, M | 1 |
| Shillingburg, A | 1 |
| Paul, S | 1 |
| Biondo, L | 1 |
| Kurhe, Y | 1 |
| Mahesh, R | 1 |
| Urien, S | 1 |
| Doz, F | 1 |
| Giraud, C | 1 |
| Rey, E | 1 |
| Gentet, JC | 1 |
| Chastagner, P | 1 |
| Vassal, G | 1 |
| Corradini, N | 1 |
| Auvrignon, A | 1 |
| Leblond, P | 1 |
| Rubie, H | 1 |
| Treluyer, JM | 1 |
| Tohei, A | 1 |
| Kojima, S | 1 |
| Ikeda, M | 1 |
| Hokao, R | 1 |
| Shinoda, M | 1 |
| Tatsushima, Y | 1 |
| Egashira, N | 1 |
| Matsushita, N | 1 |
| Kurobe, K | 1 |
| Kawashiri, T | 1 |
| Yano, T | 1 |
| Oishi, R | 1 |
| Du, J | 1 |
| Li, P | 1 |
| Sun, X | 1 |
| Zhang, M | 1 |
| Wu, Q | 1 |
| Clark, MS | 1 |
| Palmiter, RD | 1 |
| DeGabriel, J | 1 |
| Foley, WJ | 1 |
| Wallis, IR | 1 |
| Khedhaier, A | 1 |
| Ben Attia, M | 1 |
| Gadacha, W | 1 |
| Sani, M | 1 |
| Bouzouita, K | 1 |
| Chouchane, L | 1 |
| Mechkouri, M | 1 |
| Reinberg, A | 1 |
| Boughattas, NA | 1 |
| Pal, GK | 1 |
| Kannan, N | 1 |
| Pal, P | 1 |
| Rose, JB | 1 |
| McCloskey, JJ | 1 |
| Mizoguchi, H | 1 |
| Shirayama, N | 1 |
| Tsuda, M | 1 |
| Yoshiike, M | 1 |
| Suzuki, T | 1 |
| Misawa, M | 1 |
| Polati, E | 1 |
| Verlato, G | 1 |
| Finco, G | 1 |
| Mosaner, W | 1 |
| Grosso, S | 1 |
| Gottin, L | 1 |
| Pinaroli, AM | 1 |
| Ischia, S | 1 |
| Goudie, AJ | 1 |
| Leathley, MJ | 1 |
6 trials available for ondansetron and Body Weight
| Article | Year |
|---|---|
Comparison of weight-adjusted dose versus fixed dose ondansetron in preventing shivering following spinal anaesthesia for caesarean deliveries.
Topics: Adult; Africa, Eastern; Anesthesia, Spinal; Body Weight; Cesarean Section; Dose-Response Relationshi | 2019 |
Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial.
Topics: Administration, Intravenous; Adult; Anesthesia, Spinal; Blood Loss, Surgical; Blood Pressure; Blood | 2018 |
Safety and efficacy of aprepitant for chemotherapy-induced nausea and vomiting in pediatric patients: a prospective, observational study.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Body Weight; Ch | 2014 |
Developmental pharmacokinetics of etoposide in 67 children: lack of dexamethasone effect.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transp | 2011 |
Rapid intravenous administration of ondansetron or metoclopramide is not associated with cardiovascular compromise in children.
Topics: Adolescent; Age Factors; Antiemetics; Blood Pressure; Body Weight; Child; Child, Preschool; Double-B | 1995 |
Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemet | 1997 |
12 other studies available for ondansetron and Body Weight
| Article | Year |
|---|---|
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo | 2023 |
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo | 2023 |
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo | 2023 |
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats.
Topics: Animals; Body Weight; Female; Humans; Male; Maternal Exposure; Ondansetron; Pregnancy; Prenatal Expo | 2023 |
Dietary Tryptophan Supplementation Alters Fat and Glucose Metabolism in a Low-Birthweight Piglet Model.
Topics: Adipose Tissue, White; Animals; Animals, Newborn; Birth Weight; Blood Glucose; Body Weight; Choleste | 2021 |
Ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Brain; Citalopram; Corticosterone; Depression; Diet | 2015 |
Effects of cyclophosphamide on the kaolin consumption (pica behavior) in five strains of adult male rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Cyclophosphamide; Eating; Hydroxyindoleacet | 2011 |
Pemirolast reduces cisplatin-induced kaolin intake in rats.
Topics: Animals; Antineoplastic Agents; Aprepitant; Biological Transport; Body Weight; Cisplatin; Dexamethas | 2011 |
[Ameliorative effect of Armillariella tabescens on cisplatin-induced gastrointestinal tract reaction in the rat].
Topics: Agaricales; Animals; Antiemetics; Antineoplastic Agents; Biological Therapy; Body Weight; Cisplatin; | 2011 |
Deciphering a neuronal circuit that mediates appetite.
Topics: Agouti-Related Protein; Animals; Appetite; Body Weight; Feeding Behavior; Female; gamma-Aminobutyric | 2012 |
The effect of excesses and deficiencies in amino acids on the feeding behaviour of the common brushtail possum (Trichosurus vulpecula).
Topics: Adaptation, Physiological; Amino Acids; Animals; Body Weight; Diet; Dose-Response Relationship, Drug | 2002 |
Circadian rhythms in toxic effects of the serotonin antagonist ondansetron in mice.
Topics: Animals; Ataxia; Body Temperature; Body Weight; Circadian Rhythm; Humans; Male; Mice; Ondansetron; R | 2003 |
Effects of injection of serotonin into nucleus caudatus on food and water intake and body weight in albino rats.
Topics: Animals; Body Weight; Buspirone; Caudate Nucleus; Dose-Response Relationship, Drug; Drinking; Eating | 2004 |
Potentiation of physical dependence on diazepam by ondansetron in rats.
Topics: Animals; Body Weight; Diazepam; Drug Synergism; Male; Ondansetron; Rats; Rats, Inbred F344; Substanc | 1994 |
Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Chlordiazepoxide; Dose-Response Relationship, Drug; Eatin | 1990 |