Page last updated: 2024-11-01

ondansetron and Bipolar Disorder

ondansetron has been researched along with Bipolar Disorder in 2 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
" In the prelevodopa era, depression and other psychiatric disorders were described in PD, but in untreated patients psychosis was rare."4.79Parkinson's disease: drug-induced psychiatric states. ( Brown, D; Factor, SA; Molho, ES; Podskalny, GD, 1995)
"Mean ondansetron exit dose was 3."3.01A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder. ( Bice, C; Holmes, T; Ivleva, E; McArdle, M; McNutt, M; Nakamura, A; Palka, J; Patel, Z; Sherwood Brown, E; Tipton, S, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Sherwood Brown, E1
McArdle, M1
Palka, J1
Bice, C1
Ivleva, E1
Nakamura, A1
McNutt, M1
Patel, Z1
Holmes, T1
Tipton, S1
Factor, SA1
Molho, ES1
Podskalny, GD1
Brown, D1

Reviews

1 review available for ondansetron and Bipolar Disorder

ArticleYear
Parkinson's disease: drug-induced psychiatric states.
    Advances in neurology, 1995, Volume: 65

    Topics: Aged; Anxiety; Bipolar Disorder; Clozapine; Depression; Electroconvulsive Therapy; Humans; Levodopa;

1995

Trials

1 trial available for ondansetron and Bipolar Disorder

ArticleYear
A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2021, Volume: 43

    Topics: Adult; Alcohol Drinking; Alcoholism; Bipolar Disorder; Double-Blind Method; Humans; Male; Middle Age

2021