ondansetron has been researched along with Biliary Cirrhosis in 6 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 9.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 9.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "Fatigue is common in primary biliary cirrhosis (PBC)." | 6.71 | A randomized, controlled crossover trial of ondansetron in patients with primary biliary cirrhosis and fatigue. ( Burak, KW; Girlan, L; Heathcote, EJ; Heslegrave, RJ; Huet, PM; Swain, M; Theal, JJ; Tomlinson, GA; Toosi, MN, 2005) |
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 5.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 5.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "Fatigue is common in primary biliary cirrhosis (PBC)." | 2.71 | A randomized, controlled crossover trial of ondansetron in patients with primary biliary cirrhosis and fatigue. ( Burak, KW; Girlan, L; Heathcote, EJ; Heslegrave, RJ; Huet, PM; Swain, M; Theal, JJ; Tomlinson, GA; Toosi, MN, 2005) |
| "Primary biliary cirrhosis (PBC), autoimmune cholangitis (AIC = AMA-negative PBC) and primary sclerosing cholangitis (PSC) are autoimmune cholestatic liver diseases." | 2.42 | [Cholestatic liver diseases]. ( Blum, HE; Kreisel, W; Opitz, OG; Thimme, R, 2004) |
| "Profound fatigue is a clinically significant complication of chronic liver disease." | 1.33 | Personal view: a potential novel treatment for fatigue complicating chronic liver disease--how should its efficacy be evaluated? ( Jones, EA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thimme, R | 1 |
| Opitz, OG | 1 |
| Blum, HE | 1 |
| Kreisel, W | 1 |
| O'Donohue, JW | 1 |
| Pereira, SP | 1 |
| Ashdown, AC | 1 |
| Haigh, CG | 1 |
| Wilkinson, JR | 1 |
| Williams, R | 1 |
| Theal, JJ | 1 |
| Toosi, MN | 1 |
| Girlan, L | 1 |
| Heslegrave, RJ | 1 |
| Huet, PM | 1 |
| Burak, KW | 1 |
| Swain, M | 1 |
| Tomlinson, GA | 1 |
| Heathcote, EJ | 1 |
| Revicki, DA | 1 |
| Jones, EA | 1 |
| Schwörer, H | 1 |
| Hartmann, H | 1 |
| Ramadori, G | 1 |
2 reviews available for ondansetron and Biliary Cirrhosis
| Article | Year |
|---|---|
[Cholestatic liver diseases].
Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruriti | 2004 |
Methodological issues and the measurement of fatigue in primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Fatigue; Humans; Liver Cirrhosis, Biliary; Ondansetron; Serotonin Antagoni | 2005 |
3 trials available for ondansetron and Biliary Cirrhosis
| Article | Year |
|---|---|
A controlled trial of ondansetron in the pruritus of cholestasis.
Topics: Adult; Aged; Aged, 80 and over; Antipruritics; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary | 2005 |
A randomized, controlled crossover trial of ondansetron in patients with primary biliary cirrhosis and fatigue.
Topics: Constipation; Cross-Over Studies; Fatigue; Headache; Humans; Liver Cirrhosis, Biliary; Middle Aged; | 2005 |
Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.
Topics: Adult; Aged; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; M | 1995 |
1 other study available for ondansetron and Biliary Cirrhosis
| Article | Year |
|---|---|
Personal view: a potential novel treatment for fatigue complicating chronic liver disease--how should its efficacy be evaluated?
Topics: Fatigue; Hepatitis C; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ondansetron; Randomized Cont | 2006 |