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ondansetron and Anticipatory Vomiting

ondansetron has been researched along with Anticipatory Vomiting in 19 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the efficacy and safety of ondansetron hydrochloride (OND) on nausea and vomiting during repeated courses of CHOP or ACOMP-B therapy in patients with malignant lymphoma."9.10[Clinical usefulness of ondansetron hydrochloride for nausea and vomiting during repeated courses of chemotherapy for malignant lymphoma--impact of prognosis announcement on anti-emetic effect and evaluation of patient perception of chemotherapy-associate ( Fujimaki, K; Fukawa, H; Harano, H; Hashimoto, Y; Hattori, M; Kanamori, H; Kodama, F; Koharasawa, H; Mohri, H; Motomura, S; Sakai, R; Takemura, S; Tanabe, J; Tomita, N, 2002)
"We investigated the efficacy of combination of ondansetron hydrochloride injection and tablet against nausea and vomiting in 22 lung cancer patients (total number of chemotherapy courses: 23) receiving chemotherapy of single-dose carboplatin (CBDCA) at a dose of 302."9.09[Effect of ondansetron hydrochloride injection and tablet against nausea and vomiting in lung cancer patients receiving carboplatin]. ( Miyamoto, Y; Oomasa, M; Teramachi, M; Tomiyama, K; Yagi, K, 1999)
"This study was undertaken to further determine the clinical value of ondansetron (OND, supplied by Qilu Pharmaceutical Company) in the prophylaxis of nausea and vomiting induced by non-cisplatin chemotherapy."9.08[Phase III clinical studies with ondansetron (Qilu) in the prophylaxis of nausea and vomiting induced by non-cisplatin chemotherapy]. ( Xu, B; Zhou, A; Zhou, J, 1997)
"The incidence of nausea and vomiting was investigated for a maximum of 7 days in 32 breast cancer patients receiving CAF (cyclophosphamide, adriamycin, 5-fluorouracil) and CMF (cyclophosphamide, methotrexate, 5-fluorouracil) therapies."7.71[Incidence of emesis in outpatients on chemotherapy for breast cancer and the clinical efficacy of ondansetron hydrochloride tablets]. ( Hayakawa, H; Ishida, T; Kusaba, T, 2002)
"The incidence of nausea and vomiting or anorexia was investigated in 16 outpatients receiving oral antimetabolites such as 5-FU (fluorouracil) as chemotherapy, during a maximum observation period of 28 days."7.70[Chronological observation of nausea and vomiting in outpatients given oral antimetabolites as chemotherapy--two patients receiving ondansetron hydrochloride tablets]. ( Ishikawa, H; Ohya, M; Sasaki, K; Yanagida, T, 2000)
"Investigated the prevalence of anticipatory nausea and vomiting (ANV) among 59 pediatric cancer patients who had routinely received ondansetron (Zofran) antiemetic therapy and determined patient- and treatment-related factors associated with ANV."7.69Variables associated with anticipatory nausea and vomiting in pediatric cancer patients receiving ondansetron antiemetic therapy. ( Barclay, DR; Bieberich, AA; Mulhern, RK; Smith, BF; Tyc, VL, 1997)
"We evaluated the efficacy and safety of ondansetron hydrochloride (OND) on nausea and vomiting during repeated courses of CHOP or ACOMP-B therapy in patients with malignant lymphoma."5.10[Clinical usefulness of ondansetron hydrochloride for nausea and vomiting during repeated courses of chemotherapy for malignant lymphoma--impact of prognosis announcement on anti-emetic effect and evaluation of patient perception of chemotherapy-associate ( Fujimaki, K; Fukawa, H; Harano, H; Hashimoto, Y; Hattori, M; Kanamori, H; Kodama, F; Koharasawa, H; Mohri, H; Motomura, S; Sakai, R; Takemura, S; Tanabe, J; Tomita, N, 2002)
"We investigated the efficacy of combination of ondansetron hydrochloride injection and tablet against nausea and vomiting in 22 lung cancer patients (total number of chemotherapy courses: 23) receiving chemotherapy of single-dose carboplatin (CBDCA) at a dose of 302."5.09[Effect of ondansetron hydrochloride injection and tablet against nausea and vomiting in lung cancer patients receiving carboplatin]. ( Miyamoto, Y; Oomasa, M; Teramachi, M; Tomiyama, K; Yagi, K, 1999)
"This study was undertaken to further determine the clinical value of ondansetron (OND, supplied by Qilu Pharmaceutical Company) in the prophylaxis of nausea and vomiting induced by non-cisplatin chemotherapy."5.08[Phase III clinical studies with ondansetron (Qilu) in the prophylaxis of nausea and vomiting induced by non-cisplatin chemotherapy]. ( Xu, B; Zhou, A; Zhou, J, 1997)
"The incidence of nausea and vomiting was investigated for a maximum of 7 days in 32 breast cancer patients receiving CAF (cyclophosphamide, adriamycin, 5-fluorouracil) and CMF (cyclophosphamide, methotrexate, 5-fluorouracil) therapies."3.71[Incidence of emesis in outpatients on chemotherapy for breast cancer and the clinical efficacy of ondansetron hydrochloride tablets]. ( Hayakawa, H; Ishida, T; Kusaba, T, 2002)
"The incidence of nausea and vomiting or anorexia was investigated in 16 outpatients receiving oral antimetabolites such as 5-FU (fluorouracil) as chemotherapy, during a maximum observation period of 28 days."3.70[Chronological observation of nausea and vomiting in outpatients given oral antimetabolites as chemotherapy--two patients receiving ondansetron hydrochloride tablets]. ( Ishikawa, H; Ohya, M; Sasaki, K; Yanagida, T, 2000)
"Investigated the prevalence of anticipatory nausea and vomiting (ANV) among 59 pediatric cancer patients who had routinely received ondansetron (Zofran) antiemetic therapy and determined patient- and treatment-related factors associated with ANV."3.69Variables associated with anticipatory nausea and vomiting in pediatric cancer patients receiving ondansetron antiemetic therapy. ( Barclay, DR; Bieberich, AA; Mulhern, RK; Smith, BF; Tyc, VL, 1997)
" Two cases of adverse reactions (hiccups and elevation of ALT and BUN) were observed in the DEX group; however, since the symptoms were all mild, we did not consider there was any problem in safety."2.70[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in lung cancer patients on cisplatin]. ( Furue, H; Horichi, N; Ikeda, M; Taguchi, T; Tsukakoshi, S, 2001)
" Adverse reactions were observed in 2 cases (2 reports of headache) in the OND group and 5 cases (2 reports of hiccups, 2 headache, 2 diarrhea, one constipation, one hot facial flushes and one elevation of gamma-GTP) in the DEX group; however, since the symptoms were all mild, we did not consider there was any problem in safety."2.70[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in gynecological cancer patients on cisplatin]. ( Eguchi, F; Furue, H; Ikeda, M; Taguchi, T; Tsukakoshi, S, 2001)
"A group of 90 breast cancer patients undergoing chemotherapy were assessed prospectively to estimate the prevalence of acute (post-treatment) and anticipatory emesis in the 1990s."1.29Acute and anticipatory emesis in breast cancer patients. ( Casado, A; Diaz-Rubio, E; Fernández-Marcos, A; López Martin, JA; Martín, M; Rodriguez-Lescure, A; Sanchez, JJ, 1996)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (47.37)18.2507
2000's10 (52.63)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, ZK1
Feng, RX1
Wang, YL1
Parker, LA1
Kwiatkowska, M1
Mechoulam, R1
Marty, M1
Richard, A1
d'Allens, H1
Fernández-Marcos, A1
Martín, M1
Sanchez, JJ1
Rodriguez-Lescure, A1
Casado, A1
López Martin, JA1
Diaz-Rubio, E1
Tyc, VL1
Mulhern, RK1
Barclay, DR1
Smith, BF1
Bieberich, AA1
Sawaguchi, K1
Yabushita, H1
Tsukada, H1
Yamada, H1
Noguchi, M1
Nakanishi, M1
Miyamoto, Y1
Yagi, K1
Teramachi, M1
Oomasa, M1
Tomiyama, K1
Miyashita, M1
Onda, M1
Ikeda, K1
Bando, K1
Hagiwara, N1
Tsuchiya, Y1
Yoshiyuki, T1
Kiyama, T1
Saito, T1
Sasajima, K1
Yamashita, K1
Sasaki, K1
Yanagida, T1
Ohya, M1
Ishikawa, H1
Oge, A1
Alkiş, N1
Oge, O1
Kartum, A1
Zhou, J2
Xu, B2
Zhou, A2
Huang, J1
Wang, Z1
Zhou, L1
Horichi, N1
Taguchi, T2
Furue, H2
Ikeda, M2
Tsukakoshi, S2
Eguchi, F1
Nishida, T1
Yakushiji, M1
Ohizumi, K1
Noda, S1
Rikimaru, T1
Matsuoka, K1
Kodama, F1
Mohri, H1
Motomura, S1
Fukawa, H1
Tanabe, J1
Koharasawa, H1
Kanamori, H1
Hashimoto, Y1
Harano, H1
Sakai, R1
Tomita, N1
Fujimaki, K1
Takemura, S1
Hattori, M1
Ishida, T1
Kusaba, T1
Hayakawa, H1
Blower, P1
Aapro, M1

Trials

10 trials available for ondansetron and Anticipatory Vomiting

ArticleYear
[Clinical studies of oral antiemetic drugs on delayed emesis induced by cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:1

    Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Carboplatin; Cisplatin; Cross-Over Studies

1999
[Effect of ondansetron hydrochloride injection and tablet against nausea and vomiting in lung cancer patients receiving carboplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Carboplatin; Female; Humans; Inj

1999
Comparison of granisetron, ondansetron and tropisetron for control of vomiting and nausea induced by cisplatin.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:1

    Topics: Adult; Antiemetics; Antineoplastic Agents; Cisplatin; Cost-Benefit Analysis; Female; Granisetron; Hu

2000
[Phase III clinical studies with ondansetron (Qilu) in the prophylaxis of nausea and vomiting induced by non-cisplatin chemotherapy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas

1997
[Phase III clinical studies with ondansetron (Qilu) in the prophylaxis of nausea and vomiting induced by cisplatin].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Child; Child, Prescho

1997
[A randomized trial of Zudan in the prophylaxis of nausea and vomiting induced by cisplatin].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1998, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Female; Humans;

1998
[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in lung cancer patients on cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:7

    Topics: Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Therapy, Combination; Femal

2001
[Examination on efficacy and safety of concurrent use of ondansetron hydrochloride and steroid in gynecological cancer patients on cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:10

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Gen

2001
[Anti-emetic effects of ondansetron hydrochloride throughout courses of cytotoxic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:1

    Topics: Administration, Oral; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Administration Sched

2002
[Clinical usefulness of ondansetron hydrochloride for nausea and vomiting during repeated courses of chemotherapy for malignant lymphoma--impact of prognosis announcement on anti-emetic effect and evaluation of patient perception of chemotherapy-associate
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:2

    Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxo

2002

Other Studies

9 other studies available for ondansetron and Anticipatory Vomiting

ArticleYear
[Current status and direction of researches on antagonizing chemical agents induced vomiting by Chinese and Western medicines].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Neoplasms; Ondanset

2004
Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting.
    Physiology & behavior, 2006, Jan-30, Volume: 87, Issue:1

    Topics: Analysis of Variance; Animals; Antiemetics; Association Learning; Cannabidiol; Cannabinoids; Conditi

2006
[Antiemetic effect of ondansetron in recurrent chemotherapy with cisplatin].
    Bulletin du cancer, 1993, Volume: 80, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Cisplatin; Female; Humans; Male; Middle Aged; Ondansetr

1993
Acute and anticipatory emesis in breast cancer patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1996, Volume: 4, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female;

1996
Variables associated with anticipatory nausea and vomiting in pediatric cancer patients receiving ondansetron antiemetic therapy.
    Journal of pediatric psychology, 1997, Volume: 22, Issue:1

    Topics: Adolescent; Antiemetics; Case-Control Studies; Child; Conditioning, Classical; Female; Humans; Male;

1997
[Effects of intravenous and oral administration of ondansetron hydrochloride on chemotherapy-induced nausea and vomiting in patients with esophageal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Administration, Oral; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin;

1999
[Chronological observation of nausea and vomiting in outpatients given oral antimetabolites as chemotherapy--two patients receiving ondansetron hydrochloride tablets].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:3

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Antiemetics; Antimetabolites, Antineoplastic; Br

2000
[Incidence of emesis in outpatients on chemotherapy for breast cancer and the clinical efficacy of ondansetron hydrochloride tablets].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:5

    Topics: Ambulatory Care; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cycl

2002
Granisetron vs ondansetron: is it a question of duration of 5-HT3 receptor blockade?
    British journal of cancer, 2002, May-20, Volume: 86, Issue:10

    Topics: Afferent Pathways; Antiemetics; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cross-Ov

2002