ondansetron has been researched along with Anesthesia in 30 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although ondansetron was considered to prevent post-anesthesia shivering during cesarean section, its efficiency remained controversial." | 9.41 | A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section. ( Cao, F; Chen, C; Liu, J; Zhang, J; Zhang, L; Zheng, G, 2023) |
| "This randomized, double-blind study evaluated the relative efficacy of palonosetron (a new, selective 5-hydroxytryptamine type 3 [5-HT(3)] receptor antagonist) and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing gynaecological laparoscopic surgery." | 9.15 | A randomized, double-blind trial of palonosetron compared with ondansetron in preventing postoperative nausea and vomiting after gynaecological laparoscopic surgery. ( Cho, EJ; Park, SK, 2011) |
| "This prospective, randomized, placebo-controlled, double-blind study was designed to evaluate the efficacy of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting (PONV) after elective craniotomy in adult patients." | 9.09 | Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy. ( Bhatia, A; Dash, HH; Kathirvel, S; Prakash, A; Shenoy, S; Subramaniam, B, 2001) |
| "Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV)." | 9.08 | Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery. ( Altrock, K; Diefenbach, C; Grond, S; Lehmann, KA; Lynch, J, 1995) |
| "To investigate the incidence of postoperative nausea and vomiting (PONV) depending on the administration time of ondansetron." | 9.08 | [Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients]. ( Kainzwaldner, A; Ploner, F, 1997) |
| "Disagreement among many underpowered studies has led to an equivocal understanding of the efficacy of the 5-HT3 antagonist ondansetron in preventing the consequences of sympathectomy after subarachnoid anesthesia." | 8.93 | Does Ondansetron Modify Sympathectomy Due to Subarachnoid Anesthesia?: Meta-analysis, Meta-regression, and Trial Sequential Analysis. ( Bin Abdulhak, AA; Flood, P; Mavridis, D; Nunemaker, MS; Terkawi, AS; Terkawi, RS; Tiouririne, M; Wetterslev, J, 2016) |
| "Considerable controversy exists regarding the efficacy of ondansetron in preventing postanesthesia shivering (PAS)." | 8.93 | Meta-analysis of randomized controlled trials on the efficacy and safety of ondansetron in preventing postanesthesia shivering. ( Hu, X; Li, K; Li, M; Tan, Y; Tang, Z; Yang, B, 2016) |
| " 5 min prior to morphine while each ferret was maintained under isoflurane-O2 anesthesia." | 7.68 | The effects of different antiemetic agents on morphine-induced emesis in ferrets. ( Essien, E; Thut, PD; Wynn, RL, 1993) |
| "To improve the pharmacological characterization of the receptors mediating 5-hydroxytryptamine (5-HT)-induced apnea the inhibitory effects of exogenous 5-HT on respiration and phrenic nerve activity (PNA) were studied in anesthetized rats." | 7.68 | Pharmacological characterization of 5-hydroxytryptamine-induced apnea in the rat. ( Goda, Y; Matsumoto, M; Saito, H; Togashi, H; Yoshioka, M, 1992) |
| "Although ondansetron was considered to prevent post-anesthesia shivering during cesarean section, its efficiency remained controversial." | 5.41 | A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section. ( Cao, F; Chen, C; Liu, J; Zhang, J; Zhang, L; Zheng, G, 2023) |
| "This randomized, double-blind study evaluated the relative efficacy of palonosetron (a new, selective 5-hydroxytryptamine type 3 [5-HT(3)] receptor antagonist) and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing gynaecological laparoscopic surgery." | 5.15 | A randomized, double-blind trial of palonosetron compared with ondansetron in preventing postoperative nausea and vomiting after gynaecological laparoscopic surgery. ( Cho, EJ; Park, SK, 2011) |
| " Before induction of anesthesia, patients were randomly allocated to receive intravenously dexamethasone (8 mg) in group D, ondansetron (4 mg) in group O, metoclopramide (10 mg) in group M, and saline (2 mL) in group P." | 5.14 | A comparative study of the antiemetic efficacy of dexamethasone, ondansetron, and metoclopramide in patients undergoing gynecological surgery. ( Bilgin, TE; Birbicer, H; Doruk, N; Oral, U; Ozer, Z; Tok, E, 2010) |
| "This prospective, randomized, placebo-controlled, double-blind study was designed to evaluate the efficacy of ondansetron, a 5-HT3 antagonist, in preventing postoperative nausea and vomiting (PONV) after elective craniotomy in adult patients." | 5.09 | Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy. ( Bhatia, A; Dash, HH; Kathirvel, S; Prakash, A; Shenoy, S; Subramaniam, B, 2001) |
| "Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV)." | 5.08 | Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery. ( Altrock, K; Diefenbach, C; Grond, S; Lehmann, KA; Lynch, J, 1995) |
| "To investigate the incidence of postoperative nausea and vomiting (PONV) depending on the administration time of ondansetron." | 5.08 | [Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients]. ( Kainzwaldner, A; Ploner, F, 1997) |
| " The following items: name of the anesthetist, duration of anesthesia, duration of monitoring, ventilatory status upon arrival in postoperative care unit, pain scores, nausea and vomiting scores, pain medication (morphine) and anti nausea and vomiting drug consumption (ondansetron) were extracted and analysed in order to determine exhaustivity (percentage of missing data) and accuracy of the database." | 3.81 | The use of a clinical database in an anesthesia unit: focus on its limits. ( Bourgain, JL; Eghiaian, A; Guye, ML; Motamed, C; Weil, G, 2015) |
| " Findings are as follows: the application of topical anesthetic cream is commonplace (93%), with Ametop being the primary preparation used; the intravenous route was preferred to induce anesthesia; most practitioners intubate the trachea to maintain the airway during anesthesia (79%); a muscle relaxant was employed to assist intubation of the trachea in 47% of respondents and the routine use of suxamethonium was reported to be uncommon (9%); the administration of prophylactic ondansetron and dexamethasone was reported by 79% and 70% of respondents respectively; and nonsteroidal anti-inflammatory drugs (NSAIDs) are used by 77% of individuals either pre-emptively or during the intraoperative period." | 3.75 | A national survey of the anesthetic management of tonsillectomy surgery in children. ( Allford, M; Guruswamy, V, 2009) |
| "The effects of a NK1 antagonist, GR205171, and a 5-HT3 antagonist, ondansetron, in a novel model of post-anaesthesia-induced emesis in Suncus murinus is described." | 3.70 | Inhibition of anaesthetic-induced emesis by a NK1 or 5-HT3 receptor antagonist in the house musk shrew, Suncus murinus. ( Gardner, C; Perren, M, 1998) |
| "The potency of Ondansetron (Zofran, Glaxo), a highly specific 5HT3 antagonist in preventing the very unfavorable complication during introducing anesthesia, i." | 3.68 | Evaluation of ondansetron as a drug for premedication. ( Kamenova, E, 1993) |
| " 5 min prior to morphine while each ferret was maintained under isoflurane-O2 anesthesia." | 3.68 | The effects of different antiemetic agents on morphine-induced emesis in ferrets. ( Essien, E; Thut, PD; Wynn, RL, 1993) |
| "To improve the pharmacological characterization of the receptors mediating 5-hydroxytryptamine (5-HT)-induced apnea the inhibitory effects of exogenous 5-HT on respiration and phrenic nerve activity (PNA) were studied in anesthetized rats." | 3.68 | Pharmacological characterization of 5-hydroxytryptamine-induced apnea in the rat. ( Goda, Y; Matsumoto, M; Saito, H; Togashi, H; Yoshioka, M, 1992) |
| "Whereas nausea and emesis are burdensome side effects that lead to poor treatment compliance especially in chemotherapy, it is difficult to predict the emetic potential of agents in rats and mice because rodents do not vomit." | 1.38 | Enhanced gastric retention of solid resin beads as a marker for emetic potential of agents in rats. ( Ando, K; Takagi, K; Tsubone, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (40.00) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 9 (30.00) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, G | 1 |
| Zhang, J | 1 |
| Liu, J | 1 |
| Chen, C | 1 |
| Zhang, L | 1 |
| Cao, F | 1 |
| França de Moraes, GH | 1 |
| Lima, LC | 1 |
| Couceiro, TCM | 1 |
| Lins, MM | 1 |
| Cumino, DO | 1 |
| Simões, LABM | 1 |
| Mello, MJG | 1 |
| Barney, EZ | 1 |
| Fuller, ME | 1 |
| Habib, AS | 1 |
| Moore, CC | 1 |
| Bledsoe, LTR | 1 |
| Bonds, CR | 1 |
| Keller, M | 1 |
| King, CH | 1 |
| Weil, G | 1 |
| Motamed, C | 1 |
| Eghiaian, A | 1 |
| Guye, ML | 1 |
| Bourgain, JL | 1 |
| Terkawi, AS | 1 |
| Mavridis, D | 1 |
| Flood, P | 1 |
| Wetterslev, J | 1 |
| Terkawi, RS | 1 |
| Bin Abdulhak, AA | 1 |
| Nunemaker, MS | 1 |
| Tiouririne, M | 1 |
| Wolf, R | 1 |
| Morinello, E | 1 |
| Kestler, G | 1 |
| Käsmann-Kellner, B | 1 |
| Bischoff, M | 1 |
| Hager, T | 1 |
| Schöpe, J | 1 |
| Eberhart, LH | 1 |
| Li, M | 1 |
| Hu, X | 1 |
| Tan, Y | 1 |
| Yang, B | 1 |
| Li, K | 1 |
| Tang, Z | 1 |
| Allford, M | 1 |
| Guruswamy, V | 1 |
| Bilgin, TE | 1 |
| Birbicer, H | 1 |
| Ozer, Z | 1 |
| Doruk, N | 1 |
| Tok, E | 1 |
| Oral, U | 1 |
| Choi, DK | 1 |
| Chin, JH | 1 |
| Lee, EH | 1 |
| Lim, OB | 1 |
| Chung, CH | 1 |
| Ro, YJ | 1 |
| Choi, IC | 1 |
| Singh, V | 1 |
| Sinha, A | 1 |
| Prakash, N | 1 |
| Park, SK | 1 |
| Cho, EJ | 1 |
| Ando, K | 1 |
| Takagi, K | 1 |
| Tsubone, H | 1 |
| Sanjay, OP | 1 |
| Tauro, DI | 1 |
| Grond, S | 1 |
| Lynch, J | 1 |
| Diefenbach, C | 1 |
| Altrock, K | 1 |
| Lehmann, KA | 1 |
| Kamenova, E | 1 |
| Wynn, RL | 1 |
| Essien, E | 1 |
| Thut, PD | 1 |
| Tezcan, C | 1 |
| Ates, Y | 1 |
| Dönmez, A | 1 |
| Ozatamer, O | 1 |
| Morton, NS | 1 |
| Camu, F | 1 |
| Dorman, T | 1 |
| Knudsen, KE | 1 |
| Kvalsvik, O | 1 |
| Nellgard, P | 1 |
| Saint-Maurice, CP | 1 |
| Wilhelm, W | 1 |
| Cohen, LA | 1 |
| Ploner, F | 1 |
| Kainzwaldner, A | 1 |
| Gardner, C | 1 |
| Perren, M | 1 |
| Fisher, DM | 1 |
| Green, MG | 1 |
| Scarth, J | 1 |
| Dickenson, A | 1 |
| Ananthanarayan, C | 1 |
| Blight, K | 1 |
| Kathirvel, S | 1 |
| Dash, HH | 1 |
| Bhatia, A | 1 |
| Subramaniam, B | 1 |
| Prakash, A | 1 |
| Shenoy, S | 1 |
| Yoshioka, M | 1 |
| Goda, Y | 1 |
| Togashi, H | 1 |
| Matsumoto, M | 1 |
| Saito, H | 1 |
| Middlefell, VC | 1 |
| Price, TL | 1 |
| Dreteler, GH | 1 |
| Wouters, W | 1 |
| Saxena, PR | 1 |
| Kilpatrick, GJ | 1 |
| Butler, A | 1 |
| Burridge, J | 1 |
| Oxford, AW | 1 |
3 reviews available for ondansetron and Anesthesia
| Article | Year |
|---|---|
A meta-analysis of randomized controlled trials: efficiency and safety of ondansetron in preventing post-anesthesia shivering during cesarean section.
Topics: Anesthesia; Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Female; Humans; Hypotension; | 2023 |
Does Ondansetron Modify Sympathectomy Due to Subarachnoid Anesthesia?: Meta-analysis, Meta-regression, and Trial Sequential Analysis.
Topics: Anesthesia; Humans; Ondansetron; Randomized Controlled Trials as Topic; Serotonin Antagonists; Subar | 2016 |
Meta-analysis of randomized controlled trials on the efficacy and safety of ondansetron in preventing postanesthesia shivering.
Topics: Anesthesia; Humans; Ondansetron; Randomized Controlled Trials as Topic; Serotonin Antagonists; Shive | 2016 |
9 trials available for ondansetron and Anesthesia
| Article | Year |
|---|---|
A comparative study of the antiemetic efficacy of dexamethasone, ondansetron, and metoclopramide in patients undergoing gynecological surgery.
Topics: Adult; Anesthesia; Antiemetics; Dexamethasone; Female; Gynecologic Surgical Procedures; Humans; Hyst | 2010 |
Prophylactic control of post-operative nausea and vomiting using ondansetron and ramosetron after cardiac surgery.
Topics: Aged; Analgesia, Patient-Controlled; Anesthesia; Antiemetics; Benzimidazoles; Cardiac Surgical Proce | 2010 |
A randomized, double-blind trial of palonosetron compared with ondansetron in preventing postoperative nausea and vomiting after gynaecological laparoscopic surgery.
Topics: Adult; Anesthesia; Antiemetics; Demography; Double-Blind Method; Female; Gynecologic Surgical Proced | 2011 |
Midazolam: an effective antiemetic after cardiac surgery--a clinical trial.
Topics: Aged; Anesthesia; Antiemetics; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double-Blind Met | 2004 |
Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery.
Topics: Adult; Anesthesia; Double-Blind Method; Droperidol; Female; Genitalia, Female; Humans; Isoflurane; M | 1995 |
Propofol induction is more effective than ondansetron in prophylaxis of postoperative nausea, but not vomiting.
Topics: Anesthesia; Double-Blind Method; Humans; Nausea; Ondansetron; Propofol; Prospective Studies; Vomitin | 1996 |
Ondansetron reduces nausea and vomiting after paediatric adenotonsillectomy.
Topics: Adenoidectomy; Anesthesia; Antiemetics; Child; Child, Preschool; Double-Blind Method; Humans; Infant | 1997 |
[Evaluation of the administration time of ondansetron, a preventive for postoperative nausea and vomiting: prospective, randomized, double-blind study in 120 patients].
Topics: Adult; Anesthesia; Antiemetics; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Onda | 1997 |
Effect of prophylactic ondansetron on postoperative nausea and vomiting after elective craniotomy.
Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia; Antiemetics; Brain Neoplasms; Craniotomy; Dexamethas | 2001 |
18 other studies available for ondansetron and Anesthesia
| Article | Year |
|---|---|
Vomiting after intrathecal chemotherapy under anesthesia in pediatric patients with hematologic cancers: A cohort study.
Topics: Anesthesia; Antiemetics; Child; Cohort Studies; Double-Blind Method; Female; Hematologic Neoplasms; | 2024 |
Comparison of metoclopramide and promethazine for the treatment of postoperative nausea and vomiting in the post-anesthesia care unit: A retrospective database analysis.
Topics: Anesthesia; Antiemetics; Double-Blind Method; Humans; Metoclopramide; Ondansetron; Postoperative Nau | 2020 |
Preventing Postoperative Nausea and Vomiting During an Ondansetron Shortage.
Topics: Anesthesia; Antiemetics; Humans; Ondansetron; Postoperative Nausea and Vomiting | 2021 |
The use of a clinical database in an anesthesia unit: focus on its limits.
Topics: Anesthesia; Anesthesiology; Automation; Databases, Factual; Humans; Morphine; Ondansetron; Pain; Pai | 2015 |
[PONV after strabismus surgery : Risk adapted prophylaxis?].
Topics: Adolescent; Adult; Aged; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Antiemetics; | 2016 |
A national survey of the anesthetic management of tonsillectomy surgery in children.
Topics: Anesthesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Dexamet | 2009 |
Ondansetron-induced migraine-type headache.
Topics: Adult; Anesthesia; Antiemetics; Debridement; Dexamethasone; Female; Humans; Migraine Disorders; Onda | 2010 |
Enhanced gastric retention of solid resin beads as a marker for emetic potential of agents in rats.
Topics: Anesthesia; Animals; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carbon Dioxide; Ci | 2012 |
Evaluation of ondansetron as a drug for premedication.
Topics: Adult; Aged; Anesthesia; Bradycardia; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; | 1993 |
The effects of different antiemetic agents on morphine-induced emesis in ferrets.
Topics: Anesthesia; Animals; Antiemetics; Droperidol; Ferrets; Granisetron; Injections, Intravenous; Isoflur | 1993 |
Inhibition of anaesthetic-induced emesis by a NK1 or 5-HT3 receptor antagonist in the house musk shrew, Suncus murinus.
Topics: Anesthesia; Animals; Halothane; Humans; Male; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron | 1998 |
Surrogate outcomes: meaningful not!
Topics: Anesthesia; Antiemetics; Granisetron; Humans; Indoles; Ondansetron; Postoperative Nausea and Vomitin | 1999 |
An excitatory role for 5-HT in spinal inflammatory nociceptive transmission; state-dependent actions via dorsal horn 5-HT(3) receptors in the anaesthetized rat.
Topics: Anesthesia; Animals; Carrageenan; Electric Stimulation; Male; Myelitis; Nerve Fibers; Nerve Fibers, | 2000 |
Dystonic reaction after anesthesia.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Antiemetics; Dystonia; Female; Humans; Ondansetron; Pro | 2001 |
Pharmacological characterization of 5-hydroxytryptamine-induced apnea in the rat.
Topics: Anesthesia; Animals; Apnea; Bronchoconstriction; Drug Interactions; Imidazoles; Ketanserin; Male; Me | 1992 |
5-HT3 receptor agonism may be responsible for the emetic effects of zacopride in the ferret.
Topics: Anesthesia; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; | 1991 |
Comparison of the cardiovascular effects of the 5-HT1A receptor agonist flesinoxan with that of 8-OH-DPAT in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Bloo | 1990 |
1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.
Topics: Anesthesia; Animals; Biguanides; Binding, Competitive; Cats; Heart Rate; Imidazoles; In Vitro Techni | 1990 |