ondansetron has been researched along with Aging in 5 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of peripheral 5-HT3 receptors in the nociceptive behavioral response and the effect of the 5-HT3 antagonist ondansetron on indices of acute and tonic pain were investigated in the formalin test in 25- and 90-day-old Wistar male rats." | 3.74 | [Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress]. ( Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA, 2007) |
| "Ondansetron was well tolerated by all age groups with no increase in the number of adverse events observed in older volunteers." | 2.67 | Age and gender effects on ondansetron pharmacokinetics: evaluation of healthy aged volunteers. ( Benedetti, TL; Bryson, JC; Kernodle, AE; Powell, JR; Pritchard, JF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alzoubi, KH | 1 |
| Aleisa, AM | 1 |
| Alkadhi, KA | 1 |
| Butkevich, IP | 1 |
| Mikhaĭlenko, VA | 1 |
| Makukhina, GV | 1 |
| Pritchard, JF | 1 |
| Bryson, JC | 1 |
| Kernodle, AE | 1 |
| Benedetti, TL | 1 |
| Powell, JR | 1 |
| Riekkinen, P | 2 |
| Sirviö, J | 1 |
| Barnes, JM | 1 |
| Costall, B | 1 |
| Coughlan, J | 1 |
| Domeney, AM | 1 |
| Gerrard, PA | 1 |
| Kelly, ME | 1 |
| Naylor, RJ | 1 |
| Onaivi, ES | 1 |
| Tomkins, DM | 1 |
| Tyers, MB | 1 |
1 trial available for ondansetron and Aging
| Article | Year |
|---|---|
Age and gender effects on ondansetron pharmacokinetics: evaluation of healthy aged volunteers.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Evaluation Studies as Topic; Female; Hu | 1992 |
4 other studies available for ondansetron and Aging
| Article | Year |
|---|---|
In vivo expression of ganglionic long-term potentiation in superior cervical ganglia from hypertensive aged rats.
Topics: Aging; Animals; Blood Pressure; Blotting, Western; Calcineurin; Calcium-Calmodulin-Dependent Protein | 2010 |
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy; | 2007 |
Non-reversal of scopolamine- or age-related EEG changes by ondansetron, methysergide or alaproclate.
Topics: Aging; Alanine; Animals; Antidepressive Agents; Electroencephalography; Electrophysiology; Imidazole | 1991 |
The effects of ondansetron, a 5-HT3 receptor antagonist, on cognition in rodents and primates.
Topics: Aging; Animals; Arecoline; Brain; Callithrix; Choline O-Acetyltransferase; Cognition; Female; Habitu | 1990 |