Page last updated: 2024-11-01

ondansetron and Acute Myelogenous Leukemia

ondansetron has been researched along with Acute Myelogenous Leukemia in 7 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"The authors compared 2 schedules of palonosetron versus ondansetron in the treatment of chemotherapy-induced nausea and vomiting (CINV) in patients with AML receiving high-dose cytarabine."9.14Daily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia. ( Bekele, BN; Blamble, DA; Borthakur, G; Cabanillas, M; Cortes, JE; Kantarjian, H; Mattiuzzi, GN; O'Brien, S; Xiao, L, 2010)
"One hundred sixteen cases of leukemia patients received supra-high single dose TBI for bone marrow transplantation (BMT) with total a radiation dosage of 700-770 Gy at about 5cGy/min."6.68[Ondansetron in the prophylaxis of acute emesis induced by supra-high single dose total body irradiation (TBI)]. ( Fan, Y; Guo, N; Huang, X, 1995)
"The authors compared 2 schedules of palonosetron versus ondansetron in the treatment of chemotherapy-induced nausea and vomiting (CINV) in patients with AML receiving high-dose cytarabine."5.14Daily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia. ( Bekele, BN; Blamble, DA; Borthakur, G; Cabanillas, M; Cortes, JE; Kantarjian, H; Mattiuzzi, GN; O'Brien, S; Xiao, L, 2010)
"One hundred sixteen cases of leukemia patients received supra-high single dose TBI for bone marrow transplantation (BMT) with total a radiation dosage of 700-770 Gy at about 5cGy/min."2.68[Ondansetron in the prophylaxis of acute emesis induced by supra-high single dose total body irradiation (TBI)]. ( Fan, Y; Guo, N; Huang, X, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, H1
Yin, JY1
Xu, YJ1
Li, X1
Zhang, Y1
Liu, ZG1
Zhou, F1
Zhai, M1
Li, Y1
Li, XP1
Wang, Y1
Zhou, HH1
Liu, ZQ1
Mattiuzzi, GN1
Cortes, JE1
Blamble, DA1
Bekele, BN1
Xiao, L1
Cabanillas, M1
Borthakur, G1
O'Brien, S1
Kantarjian, H1
Huang, X1
Guo, N1
Fan, Y1
Colquhoun, JP1
Krstenansky, PM1
Petree, J1
Long, G1
Sundström, GM1
Wahlin, A1
Yano, K1
Matsui, H1
Fujisawa, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.[NCT03606369]Phase 2/Phase 3560 participants (Anticipated)Interventional2015-11-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for ondansetron and Acute Myelogenous Leukemia

ArticleYear
Daily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia.
    Cancer, 2010, Dec-15, Volume: 116, Issue:24

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administr

2010
[Ondansetron in the prophylaxis of acute emesis induced by supra-high single dose total body irradiation (TBI)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1995, Volume: 17, Issue:1

    Topics: Adult; Female; Humans; Leukemia, Myeloid, Acute; Male; Nausea; Ondansetron; Precursor Cell Lymphobla

1995
Comparison of efficacies of ondansetron and dixyrazine for prophylaxis of emesis during induction treatment in acute myelogenous leukemia. A pilot study.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amsacrine; Antiemetics; Antineoplastic Combined Chemotherapy Protoco

1997

Other Studies

4 other studies available for ondansetron and Acute Myelogenous Leukemia

ArticleYear
Association of ABCB1 polymorphisms with the efficacy of ondansetron in chemotherapy-induced nausea and vomiting.
    Clinical therapeutics, 2014, Aug-01, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Alleles; Antiemetics; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2014
The mark of Zorro.
    Australian family physician, 1994, Volume: 23, Issue:7

    Topics: Acyclovir; Aged; Anecdotes as Topic; Family Practice; Female; Herpes Zoster Oticus; Humans; Leukemia

1994
Extrapyramidal reaction caused by ondansetron.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:2

    Topics: Adult; Basal Ganglia Diseases; Humans; Leukemia, Myeloid, Acute; Lorazepam; Male; Ondansetron

1994
[Oral administration of cytarabine ocfosfate and ondansetron hydrochloride in patients with acute myeloid leukemia who can not be treated with intensive chemotherapy:--attempt to make their quality of life better].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Arabinonucleotides; Cytidine Monophosphate; Drug Ad

1998