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ondansetron and Acute Liver Injury, Drug-Induced

ondansetron has been researched along with Acute Liver Injury, Drug-Induced in 11 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
" Together with these new biomarkers of hepatotoxicity, a 12-hour acetylcysteine protocol offers clinicians and patients the possibility for better targeting of therapy, fewer adverse effects, a simpler dosing regimen, and shorter hospital stay."1.42Changing the Management of Paracetamol Poisoning. ( Bateman, DN, 2015)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Gomollón, F1
Rubio, S1
Charro, M1
García-López, S1
Muñoz, F1
Gisbert, JP1
Domènech, E1
Bateman, DN2
Vliegenthart, A1
Kimmitt, RA1
Seymour, JH1
Homer, NZ1
Clarke, JI1
Eddleston, M1
Gray, A1
Wood, DM1
Dargan, PI1
Cooper, JG1
Antoine, DJ1
Webb, DJ1
Lewis, SC1
Dear, JW1
Janeiro, M1
Camblor, E1
Fernández, R1
Núñez, D1
Kosmidis, PA1
Kalofonos, HP1
Christodoulou, C1
Syrigos, K1
Makatsoris, T1
Skarlos, D1
Bakogiannis, C1
Nicolaides, C1
Bafaloukos, D1
Bamias, A1
Samantas, E1
Xiros, N1
Boukovinas, I1
Fountzilas, G1
Dimopoulos, MA1
Hall, TJ1
James, PR1
Cambridge, G1

Reviews

1 review available for ondansetron and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Trials

1 trial available for ondansetron and Acute Liver Injury, Drug-Induced

ArticleYear
Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino

2008

Other Studies

9 other studies available for ondansetron and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
[Reccomendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the use of methotrexate in inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2015, Volume: 38, Issue:1

    Topics: Adult; Antiemetics; Antirheumatic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Inju

2015
Changing the Management of Paracetamol Poisoning.
    Clinical therapeutics, 2015, Volume: 37, Issue:9

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Anaphylaxis; Antidotes; Antiemetics; Biomar

2015
Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury.
    Clinical pharmacology and therapeutics, 2017, Volume: 101, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Alanine Transaminase; Analgesics, Non-Narcotic; Antiemetics; A

2017
[Narcolepsy and anesthesia].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:3

    Topics: Analgesia, Epidural; Anesthesia, Intravenous; Antiemetics; Benzhydryl Compounds; Chemical and Drug I

2007
Development of an in vitro hepatotoxicity assay for assessing the effects of chronic drug exposure.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 79, Issue:2

    Topics: Acetaminophen; Amitriptyline; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Hu

1993