Page last updated: 2024-11-01

ondansetron and Acathisia, Drug-Induced

ondansetron has been researched along with Acathisia, Drug-Induced in 3 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"Akathisia, a distressing movement disorder induced by butyrophenones, has been described with low doses of droperidol used for postoperative nausea and vomiting (PONV) prophylaxis, but the incidence remains unclear."9.27Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial. ( Charton, A; Diemunsch, P; Faitot, V; Greib, N; Joshi, GP; Meyer, N; Noudem, Y; Ruimy, A, 2018)
"Metoclopramide was ineffective."6.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)
"Akathisia, a distressing movement disorder induced by butyrophenones, has been described with low doses of droperidol used for postoperative nausea and vomiting (PONV) prophylaxis, but the incidence remains unclear."5.27Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial. ( Charton, A; Diemunsch, P; Faitot, V; Greib, N; Joshi, GP; Meyer, N; Noudem, Y; Ruimy, A, 2018)
"Ondansetron, a new 5-HT3 receptor antagonist, has been compared with high-dose metoclopramide in the control of acute emesis (24 h) induced by cisplatin (greater than or equal to 100 mg/m2)."5.07Progress in the control of acute and delayed emesis induced by cisplatin. ( Gandara, DR, 1991)
"Metoclopramide was ineffective."2.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Charton, A1
Greib, N1
Ruimy, A1
Faitot, V1
Noudem, Y1
Joshi, GP1
Meyer, N1
Diemunsch, P1
Desilva, PH1
Darvish, AH1
McDonald, SM1
Cronin, MK1
Clark, K1
Gandara, DR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Etude de l'Effet du dropéridol et de l'Ondansetron Sur l'Incidence de l'Akathisie Post opératoire en Chirurgie Ambulatoire[NCT01942343]Phase 3300 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for ondansetron and Acathisia, Drug-Induced

ArticleYear
Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial.
    European journal of anaesthesiology, 2018, Volume: 35, Issue:12

    Topics: Adult; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Antiemetics; Double-Blind Method; Dr

2018
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension

1995
Progress in the control of acute and delayed emesis induced by cisplatin.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27 Suppl 1

    Topics: Akathisia, Drug-Induced; Cisplatin; Dystonia; Humans; Imidazoles; Metoclopramide; Ondansetron; Serot

1991