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ondansetron and Absence Seizure

ondansetron has been researched along with Absence Seizure in 11 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"To document ondansetron-induced dystonia, hypoglycemia, and seizures in a child."7.77Ondansetron-induced dystonia, hypoglycemia, and seizures in a child. ( Manchanda, S; Mittal, S; Patel, A; Puliyel, JM, 2011)
"A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection."5.35Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009)
"To document ondansetron-induced dystonia, hypoglycemia, and seizures in a child."3.77Ondansetron-induced dystonia, hypoglycemia, and seizures in a child. ( Manchanda, S; Mittal, S; Patel, A; Puliyel, JM, 2011)
"PTZ-kindled mice showed high seizure activity, hippocampal neuronal loss, and expression of growth-associated phosphoprotein (GAP-43) compared with saline-treated mice."1.42Fluvoxamine alleviates seizure activity and downregulates hippocampal GAP-43 expression in pentylenetetrazole-kindled mice: role of 5-HT3 receptors. ( Alhaj, MW; Moustafa, YM; Zaitone, SA, 2015)
"Firstly, seizure latency was significantly prolonged by a 5-HT3 receptor agonist SR 57227 in a dose-dependent manner."1.40The anticonvulsant effects of SR 57227 on pentylenetetrazole-induced seizure in mice. ( Cui, R; Dong, X; Li, B; Liu, C; Lv, J; Shao, D; Song, Y; Sun, Z; Wang, L; Wang, P; Zhang, X; Zhao, J; Zhou, Y, 2014)
"Ondansetron is a highly selective 5-hydroxytryptamine 3 (5-HT(3)) receptor antagonist used as antiemetic agent for chemotherapy-, and radiotherapy-induced nausea and vomiting."1.38Evaluation of anticonvulsant and nootropic effect of ondansetron in mice. ( Agarwal, NB; Jain, S; Mediratta, PK; Sharma, KK, 2012)
"A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection."1.35Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009)
"The effects of seizures were observed to a much larger extent in malformed than in normal brain tissue."1.33Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development. ( Bassanini, S; Battaglia, G; Caccia, S; Chimenti, S; Gagliardi, B; Guiso, G; Marchi, N; Noé, F; Ravizza, T; Rizzi, M; Vezzani, A, 2006)
" Further detailed pharmacokinetic studies of irinotecan in patients receiving concomitant therapy with enzyme-inducing anticonvulsants are required so that rational dosing recommendations can be provided for this patient population."1.31Influence of phenytoin on the disposition of irinotecan: a case report. ( Berg, S; Bernstein, M; Blaney, SM; Cherrick, I; Kuttesch, N; Murry, DJ; Salama, V, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, B1
Wang, L1
Sun, Z1
Zhou, Y1
Shao, D1
Zhao, J1
Song, Y1
Lv, J1
Dong, X1
Liu, C1
Wang, P1
Zhang, X1
Cui, R1
Alhaj, MW1
Zaitone, SA1
Moustafa, YM1
Mishra, A1
Goel, RK1
George, M1
Al-Duaij, N1
O'Donnell, KA1
Shannon, MW1
Singh, NN1
Rai, A1
Selhorst, JB1
Acharya, JN1
Patel, A1
Mittal, S1
Manchanda, S1
Puliyel, JM1
Jain, S1
Agarwal, NB1
Mediratta, PK1
Sharma, KK1
Marchi, N1
Guiso, G1
Caccia, S1
Rizzi, M1
Gagliardi, B1
Noé, F1
Ravizza, T1
Bassanini, S1
Chimenti, S1
Battaglia, G1
Vezzani, A1
Sargent, AI1
Deppe, SA1
Chan, FA1
Sharma, A1
Raina, V1
Murry, DJ1
Cherrick, I1
Salama, V1
Berg, S1
Bernstein, M1
Kuttesch, N1
Blaney, SM1

Other Studies

11 other studies available for ondansetron and Absence Seizure

ArticleYear
The anticonvulsant effects of SR 57227 on pentylenetetrazole-induced seizure in mice.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Hippocampus; Male; Mice, Inbred ICR; Ondansetron;

2014
Fluvoxamine alleviates seizure activity and downregulates hippocampal GAP-43 expression in pentylenetetrazole-kindled mice: role of 5-HT3 receptors.
    Behavioural pharmacology, 2015, Volume: 26, Issue:4

    Topics: Animals; Anticonvulsants; Cell Death; Disease Models, Animal; Fluvoxamine; GAP-43 Protein; Hippocamp

2015
Chronic 5-HT
    Neuroscience, 2016, Dec-17, Volume: 339

    Topics: Animals; Anticonvulsants; Biguanides; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus

2016
Obtundation and seizure following ondansetron overdose in an infant.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:10

    Topics: Antiemetics; Humans; Infant; Male; Ondansetron; Poisoning; Seizures; Treatment Outcome; Unconsciousn

2008
Ondansetron and seizures.
    Epilepsia, 2009, Volume: 50, Issue:12

    Topics: Adult; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans;

2009
Ondansetron-induced dystonia, hypoglycemia, and seizures in a child.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:1

    Topics: Antiemetics; Child, Preschool; Dystonia; Humans; Hypoglycemia; Male; Ondansetron; Seizures; Serotoni

2011
Evaluation of anticonvulsant and nootropic effect of ondansetron in mice.
    Human & experimental toxicology, 2012, Volume: 31, Issue:9

    Topics: Animals; Anticonvulsants; Behavior, Animal; Electroshock; Male; Mice; Nootropic Agents; Ondansetron;

2012
Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development.
    Neurobiology of disease, 2006, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood

2006
Seizure associated with ondansetron.
    Clinical pharmacy, 1993, Volume: 12, Issue:8

    Topics: Adult; Gram-Negative Bacterial Infections; Humans; Male; Nausea; Ondansetron; Seizures; Shock, Septi

1993
Generalised seizures following ondansetron.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:1

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epi

2001
Influence of phenytoin on the disposition of irinotecan: a case report.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2

    Topics: Adolescent; Anticonvulsants; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy

2002